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FB:l(3)mbt
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | l(3)mbt ( synonyms: CG5954, L(3)MBT, L(3)MBT/LIN-61, L(3)mbt, L3mbt, MBT, dl(3)MBT, l(3)malignant braintumor, mbt, tumor-supressor ) | |
| Protein Name(s) | lethal (3) malignant brain tumor, | |
| External Links | ||
| FB | FBgn0002441 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0180259 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAD28799.1 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0201281 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011766 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAD28799.1 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0215050 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0215050 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007347 |
regulation of preblastoderm mitotic cell cycle |
FB:FBrf0167649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007405 |
neuroblast proliferation |
FB:FBrf0188152 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008285 |
negative regulation of cell proliferation |
FB:FBrf0215050 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010629 |
negative regulation of gene expression |
FB:FBrf0201281 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031523 |
Myb complex |
FB:FBrf0180259 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035190 |
syncytial nuclear migration |
FB:FBrf0167649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043035 |
chromatin insulator sequence binding |
FB:FBrf0215050 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lewis PW et al. (2004) Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev 18: 2929-40 PubMed GONUTS page
- ↑ 2.0 2.1 Lu J et al. (2007) A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc Natl Acad Sci U S A 104: 9381-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Richter C et al. (2011) The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nat Cell Biol 13: 1029-39 PubMed GONUTS page
- ↑ 4.0 4.1 Yohn CB et al. (2003) l(3)malignant brain tumor and three novel genes are required for Drosophila germ-cell formation. Genetics 165: 1889-900 PubMed GONUTS page
- ↑ Caussinus E & Gonzalez C (2005) Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet 37: 1125-9 PubMed GONUTS page
- ↑ 6.0 6.1 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
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