![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:l(2)gd1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | l(2)gd1 ( synonyms: CG4713, SH495, gd, l(2)SH0495, l(2)SH2 0495, l(2)gd, l(2)giant disc, l((2))gd, lethal (2) SH0495, lethal (2) giant discs, lethal giant discs, lethal(2) giant discs, lgd ) | |
| Protein Name(s) | lethal (2) giant discs 1, | |
| External Links | ||
| FB | FBgn0261983 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005543 |
phospholipid binding |
FB:FBrf0192039 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0192831 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0193163 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006886 |
intracellular protein transport |
FB:FBrf0192831 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007423 |
sensory organ development |
FB:FBrf0158846 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007472 |
wing disc morphogenesis |
FB:FBrf0158846 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008586 |
imaginal disc-derived wing vein morphogenesis |
FB:FBrf0158846 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008593 |
regulation of Notch signaling pathway |
FB:FBrf0192039 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016197 |
endosome transport |
FB:FBrf0193163 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016324 |
apical plasma membrane |
FB:FBrf0193163 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030100 |
regulation of endocytosis |
FB:FBrf0192039 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045035 |
sensory organ precursor cell division |
FB:FBrf0192039 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0192831 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0193163 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0158846 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gallagher CM & Knoblich JA (2006) The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell 11: 641-53 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Childress JL et al. (2006) Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Curr Biol 16: 2228-33 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Jaekel R & Klein T (2006) The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev Cell 11: 655-69 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Klein T (2003) The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch to the dorsoventral boundary during Drosophila wing development. Dev Biol 255: 313-33 PubMed GONUTS page
acei |
i cont.npr |
sw |