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FB:l(2)gd1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) l(2)gd1 ( synonyms: CG4713, SH495, gd, l(2)SH0495, l(2)SH2 0495, l(2)gd, l(2)giant disc, l((2))gd, lethal (2) SH0495, lethal (2) giant discs, lethal giant discs, lethal(2) giant discs, lgd )
Protein Name(s) lethal (2) giant discs 1,
External Links
FB FBgn0261983

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005543

phospholipid binding

FB:FBrf0192039
PMID:17084357[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005737

cytoplasm

FB:FBrf0192831
PMID:17088062[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0193163
PMID:17084358[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006886

intracellular protein transport

FB:FBrf0192831
PMID:17088062[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007423

sensory organ development

FB:FBrf0158846
PMID:12648493[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007472

wing disc morphogenesis

FB:FBrf0158846
PMID:12648493[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0158846
PMID:12648493[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008593

regulation of Notch signaling pathway

FB:FBrf0192039
PMID:17084357[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016197

endosome transport

FB:FBrf0193163
PMID:17084358[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016324

apical plasma membrane

FB:FBrf0193163
PMID:17084358[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0030100

regulation of endocytosis

FB:FBrf0192039
PMID:17084357[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045035

sensory organ precursor cell division

FB:FBrf0192039
PMID:17084357[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045746

negative regulation of Notch signaling pathway

FB:FBrf0192831
PMID:17088062[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045746

negative regulation of Notch signaling pathway

FB:FBrf0193163
PMID:17084358[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0158846
PMID:12648493[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Gallagher CM & Knoblich JA (2006) The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell 11: 641-53 PubMed GONUTS page
  2. 2.0 2.1 2.2 Childress JL et al. (2006) Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Curr Biol 16: 2228-33 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Jaekel R & Klein T (2006) The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev Cell 11: 655-69 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Klein T (2003) The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch to the dorsoventral boundary during Drosophila wing development. Dev Biol 255: 313-33 PubMed GONUTS page
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