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FB:l(1)sc

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) l(1)sc ( synonyms: AS-C T3, AS-T3, ASC-T3, CG3839, EG:198A6.2, L'Sc, L'sc, L(1)sc, Lethal of Scute, Lethal of scute, Lethal(1)scute, Lethal-scute, T3, ascT3, bHLHc28, l'sc, l(1)1Ba, l-sc, l(1)sc, lethal at scute, lethal of Scute, lsc, sc/T3 )
Protein Name(s) lethal of scute,
External Links
FB FBgn0002561

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P50553

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0123492

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P50553

C

From FB

GO:0005667

transcription factor complex

FB:FBrf0053886
PMID:1915272[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

C

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P50553

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0123492

NAS: Non-traceable Author Statement

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0158840
PMID:12593977[2]

TAS: Traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0123492

NAS: Non-traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0151529
PMID:12142008[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0007419

ventral cord development

FB:FBrf0158840
PMID:12593977[2]

TAS: Traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0123492

NAS: Non-traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0151529
PMID:12142008[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0007518

myoblast cell fate determination

FB:FBrf0108595
PMID:10218153[4]

TAS: Traceable Author Statement

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0075104
PMID:7821225[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0108816
PMID:10373509[6]

IDA: Inferred from Direct Assay

F

From FB

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0053886
PMID:1915272[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0065441
PMID:8565819[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0053776
PMID:1764999[8]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0053886
PMID:1915272[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0065441
PMID:8565819[7]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0075104
PMID:7821225[5]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0108816
PMID:10373509[6]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

GO:0061331

epithelial cell proliferation involved in Malpighian tubule morphogenesis

FB:FBrf0144843
PMID:11861476[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0061382

Malpighian tubule tip cell differentiation

FB:FBrf0075100
PMID:7821213[10]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

FB:FBrf0065441
PMID:8565819[7]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB

contributes_to

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0053886
PMID:1915272[1]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0043565

sequence-specific DNA binding

FB:FBrf0053776
PMID:1764999[8]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0043565

sequence-specific DNA binding

FB:FBrf0053886
PMID:1915272[1]

IPI: Inferred from Physical Interaction

FB:FBgn0000413

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Cabrera CV & Alonso MC (1991) Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila. EMBO J 10: 2965-73 PubMed GONUTS page
  2. 2.0 2.1 Skeath JB & Thor S (2003) Genetic control of Drosophila nerve cord development. Curr Opin Neurobiol 13: 8-15 PubMed GONUTS page
  3. 3.0 3.1 Skaer N et al. (2002) Gene duplication at the achaete-scute complex and morphological complexity of the peripheral nervous system in Diptera. Trends Genet 18: 399-405 PubMed GONUTS page
  4. Bate M et al. (1999) Development of larval body wall muscles. Int Rev Neurobiol 43: 25-44 PubMed GONUTS page
  5. 5.0 5.1 Cabrera CV et al. (1994) Regulation of scute function by extramacrochaete in vitro and in vivo. Development 120: 3595-603 PubMed GONUTS page
  6. 6.0 6.1 Jennings BH et al. (1999) Target specificities of Drosophila enhancer of split basic helix-loop-helix proteins. Mol Cell Biol 19: 4600-10 PubMed GONUTS page
  7. 7.0 7.1 7.2 Jarman AP et al. (1993) The regulation and function of the helix-loop-helix gene, asense, in Drosophila neural precursors. Development 119: 19-29 PubMed GONUTS page
  8. 8.0 8.1 Van Doren M et al. (1991) The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes. Development 113: 245-55 PubMed GONUTS page
  9. Sudarsan V et al. (2002) A genetic hierarchy establishes mitogenic signalling and mitotic competence in the renal tubules of Drosophila. Development 129: 935-44 PubMed GONUTS page
  10. Hoch M et al. (1994) Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development 120: 3439-50 PubMed GONUTS page
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