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FB:klar

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) klar ( synonyms: CG17046, Klar, Klarsicht, kls, marb, marbles )
Protein Name(s) klarsicht,
External Links
FB FBgn0001316

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

FB:FBrf0111985
PMID:10556085[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003779

actin binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012315

F

From FB

GO:0005515

protein binding

FB:FBrf0187339
PMID:16051169[2]

IPI: Inferred from Physical Interaction

FB:FBgn0030608

F

From FB

GO:0005635

nuclear envelope

FB:FBrf0167866
PMID:14617811[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0200125
PMID:18820457[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005811

lipid particle

FB:FBrf0192764
PMID:16979555[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0006869

lipid transport

FB:FBrf0190315
PMID:16421189[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007018

microtubule-based movement

FB:FBrf0132100
PMID:10908588[7]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007097

nuclear migration

FB:FBrf0100645
PMID:9491895[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007097

nuclear migration

FB:FBrf0111985
PMID:10556085[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007097

nuclear migration

FB:FBrf0167866
PMID:14617811[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007097

nuclear migration

FB:FBrf0184140
PMID:15647372[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007097

nuclear migration

FB:FBrf0200125
PMID:18820457[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012315

C

From FB

GO:0016044

cellular membrane organization

FB:FBrf0155504
PMID:12526813[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030286

dynein complex

FB:FBrf0132100
PMID:10908588[7]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0031887

lipid particle transport along microtubule

FB:FBrf0100645
PMID:9491895[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031887

lipid particle transport along microtubule

FB:FBrf0184140
PMID:15647372[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035149

lumen formation, open tracheal system

FB:FBrf0187390
PMID:15848387[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035239

tube morphogenesis

FB:FBrf0155504
PMID:12526813[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042051

compound eye photoreceptor development

FB:FBrf0100645
PMID:9491895[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042623

ATPase activity, coupled

FB:FBrf0132100
PMID:10908588[7]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0048471

perinuclear region of cytoplasm

FB:FBrf0111985
PMID:10556085[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0048471

perinuclear region of cytoplasm

FB:FBrf0200125
PMID:18820457[4]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0005635

nuclear envelope

FB:FBrf0184140
PMID:15647372[9]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0005811

lipid particle

FB:FBrf0184140
PMID:15647372[9]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0005881

cytoplasmic microtubule

FB:FBrf0200125
PMID:18820457[4]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Mosley-Bishop KL et al. (1999) Molecular analysis of the klarsicht gene and its role in nuclear migration within differentiating cells of the Drosophila eye. Curr Biol 9: 1211-20 PubMed GONUTS page
  2. Welte MA et al. (2005) Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr Biol 15: 1266-75 PubMed GONUTS page
  3. 3.0 3.1 Patterson K et al. (2004) The functions of Klarsicht and nuclear lamin in developmentally regulated nuclear migrations of photoreceptor cells in the Drosophila eye. Mol Biol Cell 15: 600-10 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Kracklauer MP et al. (2007) Drosophila klaroid encodes a SUN domain protein required for Klarsicht localization to the nuclear envelope and nuclear migration in the eye. Fly (Austin) 1: 75-85 PubMed GONUTS page
  5. Cermelli S et al. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr Biol 16: 1783-95 PubMed GONUTS page
  6. Pilot F et al. (2006) Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularisation. Development 133: 711-23 PubMed GONUTS page
  7. 7.0 7.1 7.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  8. 8.0 8.1 8.2 Welte MA et al. (1998) Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics. Cell 92: 547-57 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 Guo Y et al. (2005) Organelle-specific control of intracellular transport: distinctly targeted isoforms of the regulator Klar. Mol Biol Cell 16: 1406-16 PubMed GONUTS page
  10. 10.0 10.1 Myat MM & Andrew DJ (2002) Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane. Cell 111: 879-91 PubMed GONUTS page
  11. Myat MM et al. (2005) A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea. Dev Biol 281: 38-52 PubMed GONUTS page
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