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FB:key

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) key ( synonyms: CG16910, DmIKK-gamma, DmIKKgamma, Dmikkgamma, IKK, IKK-gamma, IKKg, IKKgamma, KEY, Kenny, Key, dIKK, dIKK-gamma, dmIKKgamma )
Protein Name(s) kenny,
External Links
FB FBgn0041205

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

FB:FBrf0130083
PMID:11018014[1]

IPI: Inferred from Physical Interaction

FB:FBgn0024222

F

From FB

GO:0005634

nucleus

FB:FBrf0130083
PMID:11018014[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0130083
PMID:11018014[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006955

immune response

FB:FBrf0193652
PMID:16858400[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006963

positive regulation of antibacterial peptide biosynthetic process

FB:FBrf0130159
PMID:10980426[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0006963

positive regulation of antibacterial peptide biosynthetic process

FB:FBrf0133282

NAS: Non-traceable Author Statement

P

From FB

GO:0006963

positive regulation of antibacterial peptide biosynthetic process

FB:FBrf0134801
PMID:11017107[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0141068
PMID:11283698[5]

TAS: Traceable Author Statement

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

F

From FB

GO:0008384

IkappaB kinase activity

FB:FBrf0131014

NAS: Non-traceable Author Statement

F

From FB

GO:0008385

IkappaB kinase complex

FB:FBrf0126030

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0008385

IkappaB kinase complex

FB:FBrf0131014

NAS: Non-traceable Author Statement

C

From FB

GO:0019730

antimicrobial humoral response

FB:FBrf0131014

NAS: Non-traceable Author Statement

P

From FB

GO:0030163

protein catabolic process

FB:FBrf0130083
PMID:11018014[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0050829

defense response to Gram-negative bacterium

FB:FBrf0168033
PMID:14684822[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051607

defense response to virus

FB:FBrf0209015
PMID:19829691[7]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Silverman N et al. (2000) A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev 14: 2461-71 PubMed GONUTS page
  2. Ryu JH et al. (2006) An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. EMBO J 25: 3693-701 PubMed GONUTS page
  3. Wasserman SA (2000) Toll signaling: the enigma variations. Curr Opin Genet Dev 10: 497-502 PubMed GONUTS page
  4. Rutschmann S et al. (2000) Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nat Immunol 1: 342-7 PubMed GONUTS page
  5. Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
  6. Gobert V et al. (2003) Dual activation of the Drosophila toll pathway by two pattern recognition receptors. Science 302: 2126-30 PubMed GONUTS page
  7. Costa A et al. (2009) The Imd pathway is involved in antiviral immune responses in Drosophila. PLoS One 4: e7436 PubMed GONUTS page
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