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FB:kek1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | kek1 ( synonyms: BEST:GM02380, CG12283, CT18186, Dmkek1, GM02380, KEK1, Kek, Kek-1, Kek1, Kekkon, Kekkon 1, Kekkon-1, Kekkon1, Kekon-1, NB1, SD01674, kek, kek-1, kekkon, kekkon1, kekkonI, kekon, l(2)01433, n(2)k07332, uns, unstrung ) | |
| Protein Name(s) | kekkon-1, | |
| External Links | ||
| FB | FBgn0015399 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000910 |
cytokinesis |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0107731 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003731 |
F |
From FB |
||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0178972 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003731 |
F |
From FB |
||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0089758 |
ISM: Inferred from Sequence Model |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0174702 |
ISM: Inferred from Sequence Model |
C |
From FB |
|||
| GO:0007175 |
negative regulation of epidermal growth factor-activated receptor activity |
FB:FBrf0158927 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007175 |
negative regulation of epidermal growth factor-activated receptor activity |
FB:FBrf0178972 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0158927 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0107731 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001137 |
P |
From FB |
||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0107731 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0107731 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0110978 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0178972 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0178972 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048019 |
receptor antagonist activity |
FB:FBrf0178972 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0107731 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Ghiglione C et al. (1999) The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. Cell 96: 847-56 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Alvarado D et al. (2004) Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1. Genetics 167: 187-202 PubMed GONUTS page
- ↑ Musacchio M & Perrimon N (1996) The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS. Dev Biol 178: 63-76 PubMed GONUTS page
- ↑ Derheimer FA et al. (2004) Conservation of an inhibitor of the epidermal growth factor receptor, Kekkon1, in dipterans. Genetics 166: 213-24 PubMed GONUTS page
- ↑ 6.0 6.1 Shilo BZ (2003) Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp Cell Res 284: 140-9 PubMed GONUTS page
- ↑ van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
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