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FB:ire-1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Ire1 ( synonyms: CG4583, IRE-like, IRE1, Inositol required 1, Ire, Ire-1, dIRE1, dire-1, ire-1 ) | |
| Protein Name(s) | Inositol-requiring enzyme-1, | |
| External Links | ||
| FB | FBgn0261984 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004521 |
endoribonuclease activity |
FB:FBrf0126539 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001121 |
F |
From FB |
||
| GO:0004521 |
endoribonuclease activity |
FB:FBrf0192887 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004521 |
endoribonuclease activity |
FB:FBrf0194243 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004521 |
endoribonuclease activity |
FB:FBrf0194899 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:CAA22846 |
F |
From FB |
||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0126539 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001121 |
F |
From FB |
||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0126539 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001121 |
C |
From FB |
||
| GO:0006402 |
mRNA catabolic process |
FB:FBrf0192887 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0006986 |
response to unfolded protein |
FB:FBrf0126539 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001121 |
P |
From FB |
||
| GO:0007030 |
Golgi organization |
FB:FBrf0215221 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016020 |
membrane |
FB:FBrf0126539 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001121 |
C |
From FB |
||
| GO:0016891 |
endoribonuclease activity, producing 5'-phosphomonoesters |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0030968 |
endoplasmic reticulum unfolded protein response |
FB:FBrf0194243 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0030968 |
endoplasmic reticulum unfolded protein response |
FB:FBrf0194899 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034976 |
response to endoplasmic reticulum stress |
FB:FBrf0194243 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0043484 |
regulation of RNA splicing |
FB:FBrf0194243 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0070055 |
HAC1-type intron splice site recognition and cleavage |
FB:FBrf0194899 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hollien J & Weissman JS (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313: 104-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Plongthongkum N et al. (2007) Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster. Biochem Biophys Res Commun 354: 789-94 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ryoo HD et al. (2007) Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J 26: 242-52 PubMed GONUTS page
- ↑ 4.0 4.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Zacharogianni M et al. (2011) ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association. EMBO J 30: 3684-700 PubMed GONUTS page
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