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FB:ird5
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | ird5 ( synonyms: CG4201, DIK, DLAK, DmIKK, DmIKKBeta, DmIKKb, DmIKKbeta, DmIkkbeta, Dmikkb, Dmikkbeta, IK, IKK, IKK-beta, IKK-like protein, IKKB, IKKb, IKKbeta, IRD-5, Ik, Ikkbeta, Immune response, Ird-5, Ird5, LPS-responsive kinase, LPS-responsive-kinase, LRK, Lak, Lipopolysaccharide activated kinase, anon-89Bd, cactus kinase, dIKK, dIKK-beta, dLak, deficient 5, dmIKKbeta, ikk, ird, ird5/DmIkk(beta), mmune response deficient 5 ) | |
| Protein Name(s) | immune response deficient 5, | |
| External Links | ||
| FB | FBgn0024222 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0117991 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0123082 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0208153 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0101053 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000250 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0130083 |
IPI: Inferred from Physical Interaction |
FB:FBgn0041205 |
F |
From FB |
||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0130083 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0100747 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0101053 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0130159 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0117991 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008384 |
IkappaB kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF026524 |
F |
From FB |
||
| GO:0008384 |
IkappaB kinase activity |
FB:FBrf0126030 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008384 |
IkappaB kinase activity |
FB:FBrf0130944 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0008384 |
IkappaB kinase activity |
FB:FBrf0133852 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008385 |
IkappaB kinase complex |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF026524 |
C |
From FB |
||
| GO:0008385 |
IkappaB kinase complex |
FB:FBrf0126030 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0008385 |
IkappaB kinase complex |
FB:FBrf0130944 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008385 |
IkappaB kinase complex |
FB:FBrf0133852 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0009950 |
dorsal/ventral axis specification |
FB:FBrf0117991 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0018105 |
peptidyl-serine phosphorylation |
FB:FBrf0208153 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0019730 |
antimicrobial humoral response |
FB:FBrf0130944 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0019731 |
antibacterial humoral response |
FB:FBrf0132323 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030163 |
protein catabolic process |
FB:FBrf0130083 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045088 |
regulation of innate immune response |
FB:FBrf0208153 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051607 |
defense response to virus |
FB:FBrf0209015 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Kim YS et al. (2000) Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells. J Biol Chem 275: 2071-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ertürk-Hasdemir D et al. (2009) Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. Proc Natl Acad Sci U S A 106: 9779-84 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Silverman N et al. (2000) A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev 14: 2461-71 PubMed GONUTS page
- ↑ Wu LP & Anderson KV (1998) Regulated nuclear import of Rel proteins in the Drosophila immune response. Nature 392: 93-7 PubMed GONUTS page
- ↑ Wasserman SA (2000) Toll signaling: the enigma variations. Curr Opin Genet Dev 10: 497-502 PubMed GONUTS page
- ↑ Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Lu Y et al. (2001) The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase. Genes Dev 15: 104-10 PubMed GONUTS page
- ↑ Costa A et al. (2009) The Imd pathway is involved in antiviral immune responses in Drosophila. PLoS One 4: e7436 PubMed GONUTS page
