![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:inaD
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | inaD ( synonyms: CG3504, INAD, Ina-D, InaD, Inactivation no afterpotential D, inactivation, no after-depolarization, inactivation-no after potential D, inactivation-no-afterpotential D, inactivation-no-afterpotential-D ) | |
| Protein Name(s) | inactivation no afterpotential D, | |
| External Links | ||
| FB | FBgn0001263 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005198 |
structural molecule activity |
FB:FBrf0096480 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0005198 |
structural molecule activity |
FB:FBrf0099512 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005198 |
structural molecule activity |
FB:FBrf0099512 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0136982 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0005516 |
calmodulin binding |
FB:FBrf0123143 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005516 |
calmodulin binding |
FB:FBrf0141625 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007602 |
phototransduction |
FB:FBrf0080387 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007602 |
phototransduction |
FB:FBrf0087705 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003861 |
P |
From FB |
||
| GO:0007602 |
phototransduction |
FB:FBrf0096480 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007602 |
phototransduction |
FB:FBrf0123143 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0141625 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0091374 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002940 |
C |
From FB |
||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0091374 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003861 |
C |
From FB |
||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0096480 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003861 |
C |
From FB |
||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0096480 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004784 |
C |
From FB |
||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0096480 |
IPI: Inferred from Physical Interaction |
FB:FBgn0262738 |
C |
From FB |
||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0123143 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016027 |
inaD signaling complex |
FB:FBrf0160593 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016028 |
rhabdomere |
FB:FBrf0147176 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016028 |
rhabdomere |
FB:FBrf0190947 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016028 |
rhabdomere |
FB:FBrf0211062 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016059 |
deactivation of rhodopsin mediated signaling |
FB:FBrf0080387 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017022 |
myosin binding |
FB:FBrf0141625 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0030159 |
receptor signaling complex scaffold activity |
FB:FBrf0141625 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0031473 |
myosin III binding |
FB:FBrf0108298 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002938 |
F |
From FB |
||
| GO:0050962 |
detection of light stimulus involved in sensory perception |
FB:FBrf0192668 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Tsunoda S et al. (1997) A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature 388: 243-9 PubMed GONUTS page
- ↑ 2.0 2.1 Shieh BH et al. (1997) Association of INAD with NORPA is essential for controlled activation and deactivation of Drosophila phototransduction in vivo. Proc Natl Acad Sci U S A 94: 12682-7 PubMed GONUTS page
- ↑ Kumar R & Shieh BH (2001) The second PDZ domain of INAD is a type I domain involved in binding to eye protein kinase C. Mutational analysis and naturally occurring variants. J Biol Chem 276: 24971-7 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Montell C (1999) Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15: 231-68 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Hardie RC (2001) Phototransduction in Drosophila melanogaster. J Exp Biol 204: 3403-9 PubMed GONUTS page
- ↑ 6.0 6.1 Shieh BH & Niemeyer B (1995) A novel protein encoded by the InaD gene regulates recovery of visual transduction in Drosophila. Neuron 14: 201-10 PubMed GONUTS page
- ↑ Shieh BH & Zhu MY (1996) Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors. Neuron 16: 991-8 PubMed GONUTS page
- ↑ 8.0 8.1 Chevesich J et al. (1997) Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron 18: 95-105 PubMed GONUTS page
- ↑ Harteneck C (2003) Proteins modulating TRP channel function. Cell Calcium 33: 303-10 PubMed GONUTS page
- ↑ Bähner M et al. (2002) Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current. Neuron 34: 83-93 PubMed GONUTS page
- ↑ Wang T et al. (2005) Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171: 685-94 PubMed GONUTS page
- ↑ Sanxaridis PD & Tsunoda S (2010) A forward genetic screen in Drosophila melanogaster to identify mutations affecting INAD localization in photoreceptor cells. Fly (Austin) 4: 95-103 PubMed GONUTS page
- ↑ Wes PD et al. (1999) Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD. Nat Neurosci 2: 447-53 PubMed GONUTS page
- ↑ Popescu DC et al. (2006) Scaffolding protein INAD regulates deactivation of vision by promoting phosphorylation of transient receptor potential by eye protein kinase C in Drosophila. J Neurosci 26: 8570-7 PubMed GONUTS page