![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:ik2
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | ik2 ( synonyms: 38D.31, APTX7, CG2615, DIK2, Dik2, DmIKKepsilon, DmIKKepsilon/dIK2, Dmik2, IK2, IKK, IKK-related kinase, IKKepsilon, Ik2, Ik2/DmIKK, apoptoxin 7, dIKK, dik2, l(2)38Ea, lethal (2) 38Ea ) | |
| Protein Name(s) | IkappaB kinase-like 2, | |
| External Links | ||
| FB | FBgn0086657 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000902 |
cell morphogenesis |
FB:FBrf0193419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001578 |
microtubule bundle formation |
FB:FBrf0209571 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0194448 |
IPI: Inferred from Physical Interaction |
FB:FBgn0260635 |
F |
From FB |
||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0116347 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0193419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008219 |
cell death |
FB:FBrf0194448 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008384 |
IkappaB kinase activity |
FB:FBrf0116347 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0008385 |
IkappaB kinase complex |
FB:FBrf0116347 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008407 |
chaeta morphogenesis |
FB:FBrf0209571 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016322 |
neuron remodeling |
FB:FBrf0207681 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035160 |
maintenance of epithelial integrity, open tracheal system |
FB:FBrf0193419 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043280 |
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
FB:FBrf0194448 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045035 |
sensory organ precursor cell division |
FB:FBrf0209002 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0260635 |
P |
From FB |
||
| GO:0051493 |
regulation of cytoskeleton organization |
FB:FBrf0205990 |
IPI: Inferred from Physical Interaction |
FB:FBgn0086362 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Oshima K et al. (2006) IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis. Curr Biol 16: 1531-7 PubMed GONUTS page
- ↑ 2.0 2.1 Bitan A et al. (2010) Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle. Mol Cell Biol 30: 496-507 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Kuranaga E et al. (2006) Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs. Cell 126: 583-96 PubMed GONUTS page
- ↑ Lee HH et al. (2009) Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis. Proc Natl Acad Sci U S A 106: 6363-8 PubMed GONUTS page
- ↑ Koto A et al. (2009) Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. J Cell Biol 187: 219-31 PubMed GONUTS page
- ↑ Dubin-Bar D et al. (2008) The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis. BMC Cell Biol 9: 51 PubMed GONUTS page
acdi |
i cont.m
np |
p cont.rs |