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FB:if
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | if ( synonyms: CG9623, CT27194, If, PS 2, PS2, PS2alpha, PSalpha2, aPS2, alpha integrin, alpha-PS2-integrin, alpha2 integrin, alpha2Int, alphaPS2, alphaPS2 Integrin, alphaPS2 integrin, alphaPS2-integrin, alphaPS2C, alpha((PS2(ms8))), alpha((PS2)), alpha((PS2)) integrin, in, inf, integrin, position-specific antigen 2 ) | |
| Protein Name(s) | inflated, | |
| External Links | ||
| FB | FBgn0001250 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004872 |
receptor activity |
FB:FBrf0045784 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004872 |
receptor activity |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0193518 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0193518 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0045784 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007157 |
heterophilic cell-cell adhesion |
FB:FBrf0129868 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007160 |
cell-matrix adhesion |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0149077 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007414 |
axonal defasciculation |
FB:FBrf0201257 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007426 |
tracheal outgrowth, open tracheal system |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007427 |
epithelial cell migration, open tracheal system |
FB:FBrf0144739 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007431 |
salivary gland development |
FB:FBrf0159337 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0207774 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003889 |
P |
From FB |
||
| GO:0007475 |
apposition of dorsal and ventral imaginal disc-derived wing surfaces |
FB:FBrf0167428 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0090466 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0090466 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0129746 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007494 |
midgut development |
FB:FBrf0129746 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007608 |
sensory perception of smell |
FB:FBrf0159056 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003656 |
P |
From FB |
||
| GO:0008305 |
integrin complex |
FB:FBrf0123546 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008305 |
integrin complex |
FB:FBrf0129746 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0008305 |
integrin complex |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0008305 |
integrin complex |
FB:FBrf0167428 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0008305 |
integrin complex |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016203 |
muscle attachment |
FB:FBrf0141473 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016203 |
muscle attachment |
FB:FBrf0200693 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0029830 |
P |
From FB |
||
| GO:0016203 |
muscle attachment |
FB:FBrf0201921 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0129746 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016477 |
cell migration |
FB:FBrf0129746 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030239 |
myofibril assembly |
FB:FBrf0141473 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035160 |
maintenance of epithelial integrity, open tracheal system |
FB:FBrf0193035 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004657 |
P |
From FB |
||
| GO:0043292 |
contractile fiber |
FB:FBrf0141473 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045185 |
maintenance of protein location |
FB:FBrf0141473 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050839 |
cell adhesion molecule binding |
FB:FBrf0045784 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0050839 |
cell adhesion molecule binding |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Bogaert T et al. (1987) The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments. Cell 51: 929-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
- ↑ 3.0 3.1 Tanentzapf G et al. (2006) Multiple factors contribute to integrin-talin interactions in vivo. J Cell Sci 119: 1632-44 PubMed GONUTS page
- ↑ 4.0 4.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Stevens A & Jacobs JR (2002) Integrins regulate responsiveness to slit repellent signals. J Neurosci 22: 4448-55 PubMed GONUTS page
- ↑ Huang Z et al. (2007) Crk-associated substrate (Cas) signaling protein functions with integrins to specify axon guidance during development. Development 134: 2337-47 PubMed GONUTS page
- ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ Rosin D & Shilo BZ (2002) Branch-specific migration cues in the Drosophila tracheal system. Bioessays 24: 110-3 PubMed GONUTS page
- ↑ Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
- ↑ Jattani R et al. (2009) Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. Dev Dyn 238: 853-63 PubMed GONUTS page
- ↑ 11.0 11.1 Brower DL (2003) Platelets with wings: the maturation of Drosophila integrin biology. Curr Opin Cell Biol 15: 607-13 PubMed GONUTS page
- ↑ 12.0 12.1 Brabant MC et al. (1996) Distinct spatial and temporal functions for PS integrins during Drosophila wing morphogenesis. Development 122: 3307-17 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 13.3 13.4 Brown NH (2000) Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biol 19: 191-201 PubMed GONUTS page
- ↑ Ayyub C & Paranjape J (2002) Genetic interactions provide evidence for the role of integrins in specifying normal olfactory behavior in Drosophila melanogaster. J Neurogenet 16: 165-74 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 15.3 Bloor JW & Kiehart DP (2001) zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation. Dev Biol 239: 215-28 PubMed GONUTS page
- ↑ Estrada B et al. (2007) The transmembrane protein Perdido interacts with Grip and integrins to mediate myotube projection and attachment in the Drosophila embryo. Development 134: 4469-78 PubMed GONUTS page
- ↑ Devenport D et al. (2007) Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly. Dev Biol 308: 294-308 PubMed GONUTS page
- ↑ Levi BP et al. (2006) Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. Development 133: 2383-93 PubMed GONUTS page
