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FB:iHog

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ihog ( synonyms: CG9211, CT26314, Ihog, Interference hedgehog, Interference hedghog, iHog, interference Hedgehog )
Protein Name(s) interference hedgehog,
External Links
FB FBgn0031872

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001751

compound eye photoreceptor cell differentiation

FB:FBrf0212294
PMID:21044292[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0040388

P

From FB

GO:0005515

protein binding

FB:FBrf0192598
PMID:17077139[2]

IPI: Inferred from Physical Interaction

FB:FBgn0004644

F

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0189929
PMID:16630821[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0192598
PMID:17077139[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0008158

hedgehog receptor activity

FB:FBrf0183666

IPI: Inferred from Physical Interaction

FB:FBgn0004644

F

From FB

GO:0008201

heparin binding

FB:FBrf0192598
PMID:17077139[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0008589

regulation of smoothened signaling pathway

FB:FBrf0210906
PMID:20501592[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008589

regulation of smoothened signaling pathway

FB:FBrf0212294
PMID:21044292[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0040388

P

From FB

GO:0016021

integral to membrane

FB:FBrf0183666

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0035017

cuticle pattern formation

FB:FBrf0189929
PMID:16630821[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035222

wing disc pattern formation

FB:FBrf0189929
PMID:16630821[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035222

wing disc pattern formation

FB:FBrf0212294
PMID:21044292[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0040388

P

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0192598
PMID:17077139[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0045880

positive regulation of smoothened signaling pathway

FB:FBrf0183666

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0212294
PMID:21044292[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0040388

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Camp D et al. (2010) Ihog and Boi are essential for Hedgehog signaling in Drosophila. Neural Dev 5: 28 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 McLellan JS et al. (2006) Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc Natl Acad Sci U S A 103: 17208-13 PubMed GONUTS page
  3. 3.0 3.1 3.2 Yao S et al. (2006) The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Cell 125: 343-57 PubMed GONUTS page
  4. Yan D et al. (2010) The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development. Development 137: 2033-44 PubMed GONUTS page
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