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FB:hppy
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | hppy ( synonyms: CG7097, EP-704, GLK/KHS1, Gene 2, MAP4K3, anon-WO0153538.68, l(2)SH1261, l(2)SH2 1261, lethal (2) SH1261 ) | |
| Protein Name(s) | happyhour, | |
| External Links | ||
| FB | FBgn0263395 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0200477 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026317 |
F |
From FB |
||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF100165 |
F |
From FB |
||
| GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005083 |
small GTPase regulator activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0212911 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0200477 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026317 |
P |
From FB |
||
| GO:0006915 |
apoptotic process |
FB:FBrf0213175 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007030 |
Golgi organization |
FB:FBrf0215221 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0213175 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0211337 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0212911 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031931 |
TORC1 complex |
FB:FBrf0212911 |
IPI: Inferred from Physical Interaction |
FB:FBgn0021796 |
C |
From FB |
||
| GO:0031931 |
TORC1 complex |
FB:FBrf0212911 |
IPI: Inferred from Physical Interaction |
FB:FBgn0033272 |
C |
From FB |
||
| GO:0031931 |
TORC1 complex |
FB:FBrf0212911 |
IPI: Inferred from Physical Interaction |
FB:FBgn0037647 |
C |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0015806 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0021796 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0033272 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0036007 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0037203 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0037647 |
P |
From FB |
||
| GO:0032006 |
regulation of TOR signaling cascade |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0041191 |
P |
From FB |
||
| GO:0032008 |
positive regulation of TOR signaling cascade |
FB:FBrf0200477 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026317 |
P |
From FB |
||
| GO:0040009 |
regulation of growth rate |
FB:FBrf0211337 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0208186 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000097 |
P |
From FB |
||
| GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0208186 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0043065 |
positive regulation of apoptotic process |
FB:FBrf0212911 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0212911 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046626 |
regulation of insulin receptor signaling pathway |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005198 |
P |
From FB |
||
| GO:0046626 |
regulation of insulin receptor signaling pathway |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010379 |
P |
From FB |
||
| GO:0046626 |
regulation of insulin receptor signaling pathway |
FB:FBrf0212911 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026379 |
P |
From FB |
||
| GO:0048149 |
behavioral response to ethanol |
FB:FBrf0208186 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070328 |
triglyceride homeostasis |
FB:FBrf0211337 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Findlay GM et al. (2007) A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. Biochem J 403: 13-20 PubMed GONUTS page
- ↑ 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 Resnik-Docampo M & de Celis JF (2011) MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster. PLoS One 6: e14528 PubMed GONUTS page
- ↑ 4.0 4.1 Lam D et al. (2010) Drosophila happyhour modulates JNK-dependent apoptosis. Cell Death Dis 1: e66 PubMed GONUTS page
- ↑ Zacharogianni M et al. (2011) ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association. EMBO J 30: 3684-700 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Bryk B et al. (2010) MAP4K3 regulates body size and metabolism in Drosophila. Dev Biol 344: 150-7 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Corl AB et al. (2009) Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell 137: 949-60 PubMed GONUTS page
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