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FB:hk

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) hk ( synonyms: CG10653, Hook, dHk )
Protein Name(s) hook,
External Links
FB FBgn0001202

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000226

microtubule cytoskeleton organization

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008636

P

From FB

GO:0005737

cytoplasm

FB:FBrf0126829
PMID:10751143[1]

NAS: Non-traceable Author Statement

C

From FB

GO:0005768

endosome

FB:FBrf0135226
PMID:11238449[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0006897

endocytosis

FB:FBrf0088344
PMID:8682859[3]

IEP: Inferred from Expression Pattern

P

From FB

GO:0006897

endocytosis

FB:FBrf0088344
PMID:8682859[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006897

endocytosis

FB:FBrf0106787
PMID:9927460[4]

IEP: Inferred from Expression Pattern

P

From FB

GO:0006897

endocytosis

FB:FBrf0126829
PMID:10751143[1]

TAS: Traceable Author Statement

P

From FB

GO:0006897

endocytosis

FB:FBrf0129916
PMID:10929403[5]

TAS: Traceable Author Statement

P

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008017

microtubule binding

FB:FBrf0135226
PMID:11238449[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0201586
PMID:17435236[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016197

endosome transport

FB:FBrf0108281
PMID:10218159[8]

TAS: Traceable Author Statement

P

From FB

GO:0030705

cytoskeleton-dependent intracellular transport

FB:FBrf0135226
PMID:11238449[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0045202

synapse

FB:FBrf0129990
PMID:11018772[9]

IMP: Inferred from Mutant Phenotype

C

From FB

GO:0045467

R7 cell development

FB:FBrf0129916
PMID:10929403[5]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Luzio JP et al. (2000) Lysosome-endosome fusion and lysosome biogenesis. J Cell Sci 113 ( Pt 9): 1515-24 PubMed GONUTS page
  2. 2.0 2.1 2.2 Walenta JH et al. (2001) The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins. J Cell Biol 152: 923-34 PubMed GONUTS page
  3. 3.0 3.1 Krämer H & Phistry M (1996) Mutations in the Drosophila hook gene inhibit endocytosis of the boss transmembrane ligand into multivesicular bodies. J Cell Biol 133: 1205-15 PubMed GONUTS page
  4. Krämer H & Phistry M (1999) Genetic analysis of hook, a gene required for endocytic trafficking in drosophila. Genetics 151: 675-84 PubMed GONUTS page
  5. 5.0 5.1 Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
  6. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  7. Simonsen A et al. (2007) Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. Genetics 176: 1283-97 PubMed GONUTS page
  8. Stimson DT & Ramaswami M (1999) Vesicle recycling at the Drosophila neuromuscular junction. Int Rev Neurobiol 43: 163-89 PubMed GONUTS page
  9. Narayanan R et al. (2000) Drosophila endosomal proteins hook and deep orange regulate synapse size but not synaptic vesicle recycling. J Neurobiol 45: 105-19 PubMed GONUTS page
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