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FB:hipk

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) hipk ( synonyms: CG17090, HIPK, Homeodomain interacting protein kinase, Homeodomain-interacting protein kinase, Homeodomain-interacting protein kinase 2, dhipk2, homeodomain interactin protein kinase )
Protein Name(s) homeodomain interacting protein kinase,
External Links
FB FBgn0035142

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004672

protein kinase activity

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

F

From FB

GO:0004672

protein kinase activity

FB:FBrf0206511
PMID:19088090[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0003677

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0206915
PMID:19013449[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR017441

F

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0206511
PMID:19088090[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0008013

beta-catenin binding

FB:FBrf0206511
PMID:19088090[2]

IPI: Inferred from Physical Interaction

FB:FBgn0000117

F

From FB

GO:0008134

transcription factor binding

FB:FBrf0206511
PMID:19088090[2]

IPI: Inferred from Physical Interaction

FB:FBgn0085432

F

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0206511
PMID:19088090[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008587

imaginal disc-derived wing margin morphogenesis

FB:FBrf0206511
PMID:19088090[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030177

positive regulation of Wnt receptor signaling pathway

FB:FBrf0206511
PMID:19088090[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043067

regulation of programmed cell death

FB:FBrf0200551
PMID:17682052[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0206915
PMID:19013449[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0000463

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0206915
PMID:19013449[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0001139

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0206915
PMID:19013449[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0001169

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0206915
PMID:19013449[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0004647

P

From FB

GO:0048749

compound eye development

FB:FBrf0206915
PMID:19013449[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050821

protein stabilization

FB:FBrf0206511
PMID:19088090[2]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Lee W et al. (2009) Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression. Development 136: 241-51 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Lee W et al. (2009) Hipk is an essential protein that promotes Notch signal transduction in the Drosophila eye by inhibition of the global co-repressor Groucho. Dev Biol 325: 263-72 PubMed GONUTS page
  4. Link N et al. (2007) A collective form of cell death requires homeodomain interacting protein kinase. J Cell Biol 178: 567-74 PubMed GONUTS page
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