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FB:hh
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | hh ( synonyms: CG4637, HH, Hedgehog, Hedghog, Hh, Mir, Mirabile, Moonrat, Mrt, anon-WO0134654.19, anon-WO0182946.19, bar, bar-3, bar-on-3, bar3, hg, l(3)hh, l(3)neo56, l(3)neo57 ) | |
| Protein Name(s) | hedgehog, | |
| External Links | ||
| FB | FBgn0004644 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001745 |
compound eye morphogenesis |
FB:FBrf0126773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001746 |
Bolwig's organ morphogenesis |
FB:FBrf0126773 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001751 |
compound eye photoreceptor cell differentiation |
FB:FBrf0179485 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0004175 |
endopeptidase activity |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0126658 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005113 |
patched binding |
FB:FBrf0105789 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005113 |
patched binding |
FB:FBrf0111421 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005113 |
patched binding |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005113 |
patched binding |
FB:FBrf0174381 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0192598 |
IPI: Inferred from Physical Interaction |
FB:FBgn0031872 |
F |
From FB |
||
| GO:0005576 |
extracellular region |
FB:FBrf0105789 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0105828 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0108872 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0055914 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0055914 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
FB:FBrf0141518 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006508 |
proteolysis |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0089881 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003444 |
P |
From FB |
||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0102450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0141064 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0174381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007228 |
positive regulation of hh target transcription factor activity |
FB:FBrf0105900 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001079 |
P |
From FB |
||
| GO:0007228 |
positive regulation of hh target transcription factor activity |
FB:FBrf0105900 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005355 |
P |
From FB |
||
| GO:0007267 |
cell-cell signaling |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007280 |
pole cell migration |
FB:FBrf0190201 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001205 |
P |
From FB |
||
| GO:0007280 |
pole cell migration |
FB:FBrf0190201 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0029088 |
P |
From FB |
||
| GO:0007346 |
regulation of mitotic cell cycle |
FB:FBrf0135358 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0055914 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0141518 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0187474 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007386 |
compartment pattern specification |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007398 |
ectoderm development |
FB:FBrf0134876 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007418 |
ventral midline development |
FB:FBrf0190277 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007427 |
epithelial cell migration, open tracheal system |
FB:FBrf0135726 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007440 |
foregut morphogenesis |
FB:FBrf0111439 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007442 |
hindgut morphogenesis |
FB:FBrf0111439 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007442 |
hindgut morphogenesis |
FB:FBrf0134749 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007446 |
imaginal disc growth |
FB:FBrf0173088 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007447 |
imaginal disc pattern formation |
FB:FBrf0136845 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007447 |
imaginal disc pattern formation |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0064592 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0064592 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000490 |
P |
From FB |
||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0064592 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001168 |
P |
From FB |
||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0064592 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003326 |
P |
From FB |
||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0064592 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007458 |
progression of morphogenetic furrow involved in compound eye morphogenesis |
FB:FBrf0155653 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007473 |
wing disc proximal/distal pattern formation |
FB:FBrf0158727 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007474 |
imaginal disc-derived wing vein specification |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007478 |
leg disc morphogenesis |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007487 |
analia development |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0134876 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007506 |
gonadal mesoderm development |
FB:FBrf0100771 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0134876 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0151249 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008233 |
peptidase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008347 |
glial cell migration |
FB:FBrf0145174 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0100771 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008544 |
epidermis development |
FB:FBrf0128799 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008595 |
anterior/posterior axis specification, embryo |
FB:FBrf0144780 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016015 |
morphogen activity |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0016023 |
cytoplasmic membrane-bounded vesicle |
FB:FBrf0155685 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016335 |
morphogenesis of larval imaginal disc epithelium |
FB:FBrf0190309 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016539 |
intein-mediated protein splicing |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0016540 |
protein autoprocessing |
FB:FBrf0099245 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016540 |
protein autoprocessing |
FB:FBrf0099245 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016540 |
protein autoprocessing |
FB:FBrf0108872 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016540 |
protein autoprocessing |
FB:FBrf0156738 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0021960 |
anterior commissure morphogenesis |
FB:FBrf0190277 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030139 |
endocytic vesicle |
FB:FBrf0202773 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0128450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030713 |
ovarian follicle cell stalk formation |
FB:FBrf0128450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030908 |
protein splicing |
FB:FBrf0108872 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035215 |
genital disc development |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035215 |
genital disc development |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035217 |
labial disc development |
FB:FBrf0183854 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035224 |
genital disc anterior/posterior pattern formation |
FB:FBrf0088118 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0035231 |
cytoneme assembly |
FB:FBrf0109017 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035232 |
germ cell attraction |
FB:FBrf0160454 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035277 |
spiracle morphogenesis, open tracheal system |
FB:FBrf0187474 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035288 |
anterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035289 |
posterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035290 |
trunk segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040007 |
growth |
FB:FBrf0130003 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0042078 |
germ-line stem cell division |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042078 |
germ-line stem cell division |
FB:FBrf0155987 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042127 |
regulation of cell proliferation |
FB:FBrf0137175 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0042306 |
regulation of protein import into nucleus |
FB:FBrf0167511 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042993 |
positive regulation of transcription factor import into nucleus |
FB:FBrf0132069 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043498 |
cell surface binding |
FB:FBrf0189929 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0043498 |
cell surface binding |
FB:FBrf0192598 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045464 |
R8 cell fate specification |
FB:FBrf0144824 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
FB:FBrf0108872 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
FB:FBrf0111421 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048066 |
developmental pigmentation |
FB:FBrf0162298 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048099 |
anterior/posterior lineage restriction, imaginal disc |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0158727 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0174381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0179903 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048103 |
somatic stem cell division |
FB:FBrf0155987 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048592 |
eye morphogenesis |
FB:FBrf0193969 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0060914 |
heart formation |
FB:FBrf0089772 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Suzuki T & Saigo K (2000) Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus. Development 127: 1531-40 PubMed GONUTS page
- ↑ Treisman JE (2004) Coming to our senses. Bioessays 26: 825-8 PubMed GONUTS page
- ↑ 3.0 3.1 Chen Y & Struhl G (1998) In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex. Development 125: 4943-8 PubMed GONUTS page
- ↑ 4.0 4.1 Marsh JL & Theisen H (1999) Regeneration in insects. Semin Cell Dev Biol 10: 365-75 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Ogden SK et al. (2004) Regulation of Hedgehog signaling: a complex story. Biochem Pharmacol 67: 805-14 PubMed GONUTS page
- ↑ 6.0 6.1 McLellan JS et al. (2006) Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc Natl Acad Sci U S A 103: 17208-13 PubMed GONUTS page
- ↑ Fuller MT (1998) Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol 9: 433-44 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Mohler J & Vani K (1992) Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development 115: 957-71 PubMed GONUTS page
- ↑ 9.0 9.1 Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
- ↑ van den Heuvel M & Ingham PW (1996) smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382: 547-51 PubMed GONUTS page
- ↑ Farese RV Jr & Herz J (1998) Cholesterol metabolism and embryogenesis. Trends Genet 14: 115-20 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
- ↑ 13.0 13.1 Ohlmeyer JT & Kalderon D (1998) Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396: 749-53 PubMed GONUTS page
- ↑ 14.0 14.1 Deshpande G & Schedl P (2005) HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster. Dev Cell 9: 629-38 PubMed GONUTS page
- ↑ Zhang Y & Kalderon D (2001) Hedgehog acts as a somatic stem cell factor in the Drosophila ovary. Nature 410: 599-604 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
- ↑ 17.0 17.1 Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 Chen JN & Fishman MC (2000) Genetics of heart development. Trends Genet 16: 383-8 PubMed GONUTS page
- ↑ 19.0 19.1 Bossing T & Brand AH (2006) Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. Development 133: 1001-12 PubMed GONUTS page
- ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ Glazer L & Shilo BZ (2001) Hedgehog signaling patterns the tracheal branches. Development 128: 1599-606 PubMed GONUTS page
- ↑ 22.0 22.1 Murakami R et al. (1999) Developmental genetics of the Drosophila gut: specification of primordia, subdivision and overt-differentiation. Cell Mol Biol (Noisy-le-grand) 45: 661-76 PubMed GONUTS page
- ↑ Takashima S & Murakami R (2001) Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en. Mech Dev 101: 79-90 PubMed GONUTS page
- ↑ Hafen E & Stocker H (2003) How are the sizes of cells, organs, and bodies controlled? PLoS Biol 1: E86 PubMed GONUTS page
- ↑ 25.0 25.1 Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ 26.0 26.1 26.2 26.3 26.4 Ma C et al. (1993) The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye. Cell 75: 927-38 PubMed GONUTS page
- ↑ Peters MA (2002) Patterning the neural retina. Curr Opin Neurobiol 12: 43-8 PubMed GONUTS page
- ↑ 28.0 28.1 De Celis JF (2003) Pattern formation in the Drosophila wing: The development of the veins. Bioessays 25: 443-51 PubMed GONUTS page
- ↑ 29.0 29.1 29.2 Milán M & Cohen SM (2000) Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control? Dev Biol 217: 1-9 PubMed GONUTS page
- ↑ 30.0 30.1 30.2 30.3 30.4 Sánchez L & Guerrero I (2001) The development of the Drosophila genital disc. Bioessays 23: 698-707 PubMed GONUTS page
- ↑ 31.0 31.1 Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
- ↑ Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
- ↑ Hummel T et al. (2002) Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genes. Neuron 33: 193-203 PubMed GONUTS page
- ↑ Hatini V et al. (2000) Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines. Genes Dev 14: 1364-76 PubMed GONUTS page
- ↑ Taylor MV (2002) Drosophila development: novel signal elicits visceral response. Curr Biol 12: R102-4 PubMed GONUTS page
- ↑ Gallet A et al. (2003) Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev Cell 4: 191-204 PubMed GONUTS page
- ↑ McClure KD & Schubiger G (2005) Developmental analysis and squamous morphogenesis of the peripodial epithelium in Drosophila imaginal discs. Development 132: 5033-42 PubMed GONUTS page
- ↑ 38.0 38.1 Hall TM et al. (1997) Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell 91: 85-97 PubMed GONUTS page
- ↑ Callejo A et al. (2008) Patched, the receptor of Hedgehog, is a lipoprotein receptor. Proc Natl Acad Sci U S A 105: 912-7 PubMed GONUTS page
- ↑ 40.0 40.1 Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ Joulia L et al. (2005) Homeotic proboscipedia function modulates hedgehog-mediated organizer activity to pattern adult Drosophila mouthparts. Dev Biol 278: 496-510 PubMed GONUTS page
- ↑ Freeland DE & Kuhn DT (1996) Expression patterns of developmental genes reveal segment and parasegment organization of D. melanogaster genital discs. Mech Dev 56: 61-72 PubMed GONUTS page
- ↑ RamÃrez-Weber FA & Kornberg TB (1999) Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97: 599-607 PubMed GONUTS page
- ↑ Coffman CR (2003) Cell migration and programmed cell death of Drosophila germ cells. Ann N Y Acad Sci 995: 117-26 PubMed GONUTS page
- ↑ Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
- ↑ Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ 48.0 48.1 Lin H (2002) The stem-cell niche theory: lessons from flies. Nat Rev Genet 3: 931-40 PubMed GONUTS page
- ↑ Horabin JI et al. (2003) A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch. Development 130: 6101-9 PubMed GONUTS page
- ↑ Wang G et al. (2000) Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus. Genes Dev 14: 2893-905 PubMed GONUTS page
- ↑ Yao S et al. (2006) The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Cell 125: 343-57 PubMed GONUTS page
- ↑ Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
- ↑ Wittkopp PJ et al. (2003) Evolution in black and white: genetic control of pigment patterns in Drosophila. Trends Genet 19: 495-504 PubMed GONUTS page
- ↑ Crozatier M et al. (2004) Patterns in evolution: veins of the Drosophila wing. Trends Genet 20: 498-505 PubMed GONUTS page
- ↑ Kent D et al. (2006) Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus. Development 133: 2001-10 PubMed GONUTS page
- ↑ Park M et al. (1996) The wingless signaling pathway is directly involved in Drosophila heart development. Dev Biol 177: 104-16 PubMed GONUTS page