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FB:hh

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) hh ( synonyms: CG4637, HH, Hedgehog, Hedghog, Hh, Mir, Mirabile, Moonrat, Mrt, anon-WO0134654.19, anon-WO0182946.19, bar, bar-3, bar-on-3, bar3, hg, l(3)hh, l(3)neo56, l(3)neo57 )
Protein Name(s) hedgehog,
External Links
FB FBgn0004644

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

FB:FBrf0126773
PMID:10704398[1]

TAS: Traceable Author Statement

P

From FB

GO:0001746

Bolwig's organ morphogenesis

FB:FBrf0126773
PMID:10704398[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001751

compound eye photoreceptor cell differentiation

FB:FBrf0179485
PMID:15273984[2]

TAS: Traceable Author Statement

P

From FB

GO:0004175

endopeptidase activity

FB:FBrf0156738

NAS: Non-traceable Author Statement

F

From FB

GO:0004197

cysteine-type endopeptidase activity

FB:FBrf0126658

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005113

patched binding

FB:FBrf0105789
PMID:9811578[3]

TAS: Traceable Author Statement

F

From FB

GO:0005113

patched binding

FB:FBrf0111421
PMID:10497093[4]

TAS: Traceable Author Statement

F

From FB

GO:0005113

patched binding

FB:FBrf0156738

NAS: Non-traceable Author Statement

F

From FB

GO:0005113

patched binding

FB:FBrf0174381
PMID:15104233[5]

TAS: Traceable Author Statement

F

From FB

GO:0005515

protein binding

FB:FBrf0192598
PMID:17077139[6]

IPI: Inferred from Physical Interaction

FB:FBgn0031872

F

From FB

GO:0005576

extracellular region

FB:FBrf0105789
PMID:9811578[3]

TAS: Traceable Author Statement

C

From FB

GO:0005576

extracellular region

FB:FBrf0105828
PMID:9813190[7]

TAS: Traceable Author Statement

C

From FB

GO:0005576

extracellular region

FB:FBrf0108872

TAS: Traceable Author Statement

C

From FB

GO:0005576

extracellular region

FB:FBrf0156738

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0055914
PMID:1280560[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0156738

NAS: Non-traceable Author Statement

C

From FB

GO:0005737

cytoplasm

FB:FBrf0055914
PMID:1280560[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0156738

NAS: Non-traceable Author Statement

C

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0141518
PMID:11743020[9]

TAS: Traceable Author Statement

P

From FB

GO:0006508

proteolysis

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001767

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0089881
PMID:8700230[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0003444

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0102450
PMID:9540409[11]

TAS: Traceable Author Statement

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0141064
PMID:11253649[12]

NAS: Non-traceable Author Statement

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0156738

NAS: Non-traceable Author Statement

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0174381
PMID:15104233[5]

TAS: Traceable Author Statement

P

From FB

GO:0007228

positive regulation of hh target transcription factor activity

FB:FBrf0105900
PMID:9874371[13]

IGI: Inferred from Genetic Interaction

FB:FBgn0001079

P

From FB

GO:0007228

positive regulation of hh target transcription factor activity

FB:FBrf0105900
PMID:9874371[13]

IGI: Inferred from Genetic Interaction

FB:FBgn0005355

P

From FB

GO:0007267

cell-cell signaling

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000320

P

From FB

GO:0007280

pole cell migration

FB:FBrf0190201
PMID:16256738[14]

IGI: Inferred from Genetic Interaction

FB:FBgn0001205

P

From FB

GO:0007280

pole cell migration

FB:FBrf0190201
PMID:16256738[14]

IGI: Inferred from Genetic Interaction

FB:FBgn0029088

P

From FB

GO:0007346

regulation of mitotic cell cycle

FB:FBrf0135358
PMID:11279500[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0055914
PMID:1280560[8]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0141518
PMID:11743020[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0156738

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0179912
PMID:15382142[16]

TAS: Traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0187474
PMID:15930099[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007386

compartment pattern specification

FB:FBrf0141064
PMID:11253649[12]

TAS: Traceable Author Statement

P

From FB

GO:0007398

ectoderm development

FB:FBrf0134876
PMID:10973066[18]

NAS: Non-traceable Author Statement

P

From FB

GO:0007418

ventral midline development

FB:FBrf0190277
PMID:16467357[19]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0167264
PMID:14570584[20]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0135726
PMID:11290298[21]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007440

foregut morphogenesis

FB:FBrf0111439
PMID:10512197[22]

TAS: Traceable Author Statement

P

From FB

GO:0007442

hindgut morphogenesis

FB:FBrf0111439
PMID:10512197[22]

TAS: Traceable Author Statement

P

From FB

GO:0007442

hindgut morphogenesis

FB:FBrf0134749
PMID:11231061[23]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007446

imaginal disc growth

FB:FBrf0173088
PMID:14691557[24]

TAS: Traceable Author Statement

P

From FB

GO:0007447

imaginal disc pattern formation

FB:FBrf0136845
PMID:11377964[25]

NAS: Non-traceable Author Statement

P

From FB

GO:0007447

imaginal disc pattern formation

FB:FBrf0156738

NAS: Non-traceable Author Statement

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0064592
PMID:8252628[26]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0064592
PMID:8252628[26]

IGI: Inferred from Genetic Interaction

FB:FBgn0000490

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0064592
PMID:8252628[26]

IGI: Inferred from Genetic Interaction

FB:FBgn0001168

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0064592
PMID:8252628[26]

IGI: Inferred from Genetic Interaction

FB:FBgn0003326

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0064592
PMID:8252628[26]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0155653
PMID:11861163[27]

TAS: Traceable Author Statement

P

From FB

GO:0007473

wing disc proximal/distal pattern formation

FB:FBrf0158727
PMID:12717815[28]

TAS: Traceable Author Statement

P

From FB

GO:0007474

imaginal disc-derived wing vein specification

FB:FBrf0123139
PMID:10625531[29]

TAS: Traceable Author Statement

P

From FB

GO:0007478

leg disc morphogenesis

FB:FBrf0137175
PMID:11494318[30]

TAS: Traceable Author Statement

P

From FB

GO:0007487

analia development

FB:FBrf0137175
PMID:11494318[30]

TAS: Traceable Author Statement

P

From FB

GO:0007498

mesoderm development

FB:FBrf0134876
PMID:10973066[18]

NAS: Non-traceable Author Statement

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0100771
PMID:9435287[31]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007507

heart development

FB:FBrf0134876
PMID:10973066[18]

TAS: Traceable Author Statement

P

From FB

GO:0007507

heart development

FB:FBrf0151249
PMID:12027431[32]

NAS: Non-traceable Author Statement

P

From FB

GO:0008233

peptidase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001767

F

From FB

GO:0008347

glial cell migration

FB:FBrf0145174
PMID:11804568[33]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008354

germ cell migration

FB:FBrf0100771
PMID:9435287[31]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008544

epidermis development

FB:FBrf0128799
PMID:10837029[34]

TAS: Traceable Author Statement

P

From FB

GO:0008595

anterior/posterior axis specification, embryo

FB:FBrf0144780
PMID:11839291[35]

NAS: Non-traceable Author Statement

P

From FB

GO:0016015

morphogen activity

FB:FBrf0137175
PMID:11494318[30]

TAS: Traceable Author Statement

F

From FB

GO:0016023

cytoplasmic membrane-bounded vesicle

FB:FBrf0155685
PMID:12586063[36]

IDA: Inferred from Direct Assay

C

From FB

GO:0016335

morphogenesis of larval imaginal disc epithelium

FB:FBrf0190309
PMID:16236766[37]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016539

intein-mediated protein splicing

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006141

P

From FB

GO:0016540

protein autoprocessing

FB:FBrf0099245
PMID:9335337[38]

IDA: Inferred from Direct Assay

P

From FB

GO:0016540

protein autoprocessing

FB:FBrf0099245
PMID:9335337[38]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016540

protein autoprocessing

FB:FBrf0108872

TAS: Traceable Author Statement

P

From FB

GO:0016540

protein autoprocessing

FB:FBrf0156738

NAS: Non-traceable Author Statement

P

From FB

GO:0021960

anterior commissure morphogenesis

FB:FBrf0190277
PMID:16467357[19]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030139

endocytic vesicle

FB:FBrf0202773
PMID:18198278[39]

IDA: Inferred from Direct Assay

C

From FB

GO:0030707

ovarian follicle cell development

FB:FBrf0128450
PMID:10822261[40]

TAS: Traceable Author Statement

P

From FB

GO:0030713

ovarian follicle cell stalk formation

FB:FBrf0128450
PMID:10822261[40]

TAS: Traceable Author Statement

P

From FB

GO:0030908

protein splicing

FB:FBrf0108872

TAS: Traceable Author Statement

P

From FB

GO:0035215

genital disc development

FB:FBrf0137175
PMID:11494318[30]

TAS: Traceable Author Statement

P

From FB

GO:0035215

genital disc development

FB:FBrf0187379
PMID:15893978[41]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035217

labial disc development

FB:FBrf0183854
PMID:15680366[42]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035224

genital disc anterior/posterior pattern formation

FB:FBrf0088118
PMID:8798147[43]

IEP: Inferred from Expression Pattern

P

From FB

GO:0035231

cytoneme assembly

FB:FBrf0109017
PMID:10367889[44]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035232

germ cell attraction

FB:FBrf0160454
PMID:12814944[45]

TAS: Traceable Author Statement

P

From FB

GO:0035277

spiracle morphogenesis, open tracheal system

FB:FBrf0187474
PMID:15930099[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035288

anterior head segmentation

FB:FBrf0179912
PMID:15382142[16]

TAS: Traceable Author Statement

P

From FB

GO:0035289

posterior head segmentation

FB:FBrf0179912
PMID:15382142[16]

TAS: Traceable Author Statement

P

From FB

GO:0035290

trunk segmentation

FB:FBrf0179912
PMID:15382142[16]

TAS: Traceable Author Statement

P

From FB

GO:0040007

growth

FB:FBrf0130003
PMID:11128988[46]

NAS: Non-traceable Author Statement

P

From FB

GO:0042078

germ-line stem cell division

FB:FBrf0132360
PMID:11131529[47]

TAS: Traceable Author Statement

P

From FB

GO:0042078

germ-line stem cell division

FB:FBrf0155987
PMID:12459723[48]

TAS: Traceable Author Statement

P

From FB

GO:0042127

regulation of cell proliferation

FB:FBrf0137175
PMID:11494318[30]

NAS: Non-traceable Author Statement

P

From FB

GO:0042306

regulation of protein import into nucleus

FB:FBrf0167511
PMID:14597576[49]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042993

positive regulation of transcription factor import into nucleus

FB:FBrf0132069
PMID:11090136[50]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043498

cell surface binding

FB:FBrf0189929
PMID:16630821[51]

IDA: Inferred from Direct Assay

F

From FB

GO:0043498

cell surface binding

FB:FBrf0192598
PMID:17077139[6]

IDA: Inferred from Direct Assay

F

From FB

GO:0045464

R8 cell fate specification

FB:FBrf0144824
PMID:11880339[52]

NAS: Non-traceable Author Statement

P

From FB

GO:0045880

positive regulation of smoothened signaling pathway

FB:FBrf0108872

TAS: Traceable Author Statement

P

From FB

GO:0045880

positive regulation of smoothened signaling pathway

FB:FBrf0111421
PMID:10497093[4]

TAS: Traceable Author Statement

P

From FB

GO:0046620

regulation of organ growth

FB:FBrf0136845
PMID:11377964[25]

TAS: Traceable Author Statement

P

From FB

GO:0048066

developmental pigmentation

FB:FBrf0162298
PMID:12957543[53]

TAS: Traceable Author Statement

P

From FB

GO:0048099

anterior/posterior lineage restriction, imaginal disc

FB:FBrf0123139
PMID:10625531[29]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0123139
PMID:10625531[29]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0141064
PMID:11253649[12]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0158727
PMID:12717815[28]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0174381
PMID:15104233[5]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0179903
PMID:15363904[54]

TAS: Traceable Author Statement

P

From FB

GO:0048103

somatic stem cell division

FB:FBrf0155987
PMID:12459723[48]

TAS: Traceable Author Statement

P

From FB

GO:0048592

eye morphogenesis

FB:FBrf0193969
PMID:16651542[55]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0060914

heart formation

FB:FBrf0089772
PMID:8660881[56]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ 1.0 1.1 Suzuki T & Saigo K (2000) Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus. Development 127: 1531-40 PubMed GONUTS page
  2. ↑ Treisman JE (2004) Coming to our senses. Bioessays 26: 825-8 PubMed GONUTS page
  3. ↑ 3.0 3.1 Chen Y & Struhl G (1998) In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex. Development 125: 4943-8 PubMed GONUTS page
  4. ↑ 4.0 4.1 Marsh JL & Theisen H (1999) Regeneration in insects. Semin Cell Dev Biol 10: 365-75 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 Ogden SK et al. (2004) Regulation of Hedgehog signaling: a complex story. Biochem Pharmacol 67: 805-14 PubMed GONUTS page
  6. ↑ 6.0 6.1 McLellan JS et al. (2006) Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc Natl Acad Sci U S A 103: 17208-13 PubMed GONUTS page
  7. ↑ Fuller MT (1998) Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol 9: 433-44 PubMed GONUTS page
  8. ↑ 8.0 8.1 8.2 Mohler J & Vani K (1992) Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. Development 115: 957-71 PubMed GONUTS page
  9. ↑ 9.0 9.1 Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
  10. ↑ van den Heuvel M & Ingham PW (1996) smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 382: 547-51 PubMed GONUTS page
  11. ↑ Farese RV Jr & Herz J (1998) Cholesterol metabolism and embryogenesis. Trends Genet 14: 115-20 PubMed GONUTS page
  12. ↑ 12.0 12.1 12.2 McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
  13. ↑ 13.0 13.1 Ohlmeyer JT & Kalderon D (1998) Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396: 749-53 PubMed GONUTS page
  14. ↑ 14.0 14.1 Deshpande G & Schedl P (2005) HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster. Dev Cell 9: 629-38 PubMed GONUTS page
  15. ↑ Zhang Y & Kalderon D (2001) Hedgehog acts as a somatic stem cell factor in the Drosophila ovary. Nature 410: 599-604 PubMed GONUTS page
  16. ↑ 16.0 16.1 16.2 16.3 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
  17. ↑ 17.0 17.1 Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
  18. ↑ 18.0 18.1 18.2 Chen JN & Fishman MC (2000) Genetics of heart development. Trends Genet 16: 383-8 PubMed GONUTS page
  19. ↑ 19.0 19.1 Bossing T & Brand AH (2006) Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. Development 133: 1001-12 PubMed GONUTS page
  20. ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  21. ↑ Glazer L & Shilo BZ (2001) Hedgehog signaling patterns the tracheal branches. Development 128: 1599-606 PubMed GONUTS page
  22. ↑ 22.0 22.1 Murakami R et al. (1999) Developmental genetics of the Drosophila gut: specification of primordia, subdivision and overt-differentiation. Cell Mol Biol (Noisy-le-grand) 45: 661-76 PubMed GONUTS page
  23. ↑ Takashima S & Murakami R (2001) Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en. Mech Dev 101: 79-90 PubMed GONUTS page
  24. ↑ Hafen E & Stocker H (2003) How are the sizes of cells, organs, and bodies controlled? PLoS Biol 1: E86 PubMed GONUTS page
  25. ↑ 25.0 25.1 Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
  26. ↑ 26.0 26.1 26.2 26.3 26.4 Ma C et al. (1993) The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye. Cell 75: 927-38 PubMed GONUTS page
  27. ↑ Peters MA (2002) Patterning the neural retina. Curr Opin Neurobiol 12: 43-8 PubMed GONUTS page
  28. ↑ 28.0 28.1 De Celis JF (2003) Pattern formation in the Drosophila wing: The development of the veins. Bioessays 25: 443-51 PubMed GONUTS page
  29. ↑ 29.0 29.1 29.2 Milán M & Cohen SM (2000) Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control? Dev Biol 217: 1-9 PubMed GONUTS page
  30. ↑ 30.0 30.1 30.2 30.3 30.4 Sánchez L & Guerrero I (2001) The development of the Drosophila genital disc. Bioessays 23: 698-707 PubMed GONUTS page
  31. ↑ 31.0 31.1 Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
  32. ↑ Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
  33. ↑ Hummel T et al. (2002) Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genes. Neuron 33: 193-203 PubMed GONUTS page
  34. ↑ Hatini V et al. (2000) Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines. Genes Dev 14: 1364-76 PubMed GONUTS page
  35. ↑ Taylor MV (2002) Drosophila development: novel signal elicits visceral response. Curr Biol 12: R102-4 PubMed GONUTS page
  36. ↑ Gallet A et al. (2003) Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev Cell 4: 191-204 PubMed GONUTS page
  37. ↑ McClure KD & Schubiger G (2005) Developmental analysis and squamous morphogenesis of the peripodial epithelium in Drosophila imaginal discs. Development 132: 5033-42 PubMed GONUTS page
  38. ↑ 38.0 38.1 Hall TM et al. (1997) Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell 91: 85-97 PubMed GONUTS page
  39. ↑ Callejo A et al. (2008) Patched, the receptor of Hedgehog, is a lipoprotein receptor. Proc Natl Acad Sci U S A 105: 912-7 PubMed GONUTS page
  40. ↑ 40.0 40.1 Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
  41. ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
  42. ↑ Joulia L et al. (2005) Homeotic proboscipedia function modulates hedgehog-mediated organizer activity to pattern adult Drosophila mouthparts. Dev Biol 278: 496-510 PubMed GONUTS page
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