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FB:hay
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | hay ( synonyms: CG8019, DhR25, DhXPB, DmXPB, ERCC3, Hay, Haywire, TFIIH, XPB, Xpb/hay, hwr, i50, ms(3)nc2, nc2 ) | |
| Protein Name(s) | haywire, | |
| External Links | ||
| FB | FBgn0001179 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000381 |
regulation of alternative nuclear mRNA splicing, via spliceosome |
FB:FBrf0180650 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001111 |
promoter clearance from RNA polymerase II promoter |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
P |
From FB |
||
| GO:0001113 |
transcriptional open complex formation at RNA polymerase II promoter |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
P |
From FB |
||
| GO:0003677 |
DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0004003 |
ATP-dependent DNA helicase activity |
FB:FBrf0124216 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004386 |
helicase activity |
FB:FBrf0055584 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
F |
From FB |
||
| GO:0004386 |
helicase activity |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
F |
From FB |
||
| GO:0004386 |
helicase activity |
FB:FBrf0129923 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0088007 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0124216 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0180650 |
IC: Inferred by Curator |
GO:0000381 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0201392 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0206304 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005675 |
holo TFIIH complex |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
C |
From FB |
||
| GO:0005675 |
holo TFIIH complex |
FB:FBrf0088007 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005675 |
holo TFIIH complex |
FB:FBrf0129705 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
C |
From FB |
||
| GO:0005675 |
holo TFIIH complex |
FB:FBrf0129705 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001405 |
C |
From FB |
||
| GO:0006289 |
nucleotide-excision repair |
FB:FBrf0055584 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
P |
From FB |
||
| GO:0006289 |
nucleotide-excision repair |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
P |
From FB |
||
| GO:0006366 |
transcription from RNA polymerase II promoter |
FB:FBrf0180712 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006367 |
transcription initiation from RNA polymerase II promoter |
FB:FBrf0129705 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
P |
From FB |
||
| GO:0006367 |
transcription initiation from RNA polymerase II promoter |
FB:FBrf0129705 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001405 |
P |
From FB |
||
| GO:0008344 |
adult locomotory behavior |
FB:FBrf0055584 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009411 |
response to UV |
FB:FBrf0055584 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
FB:FBrf0057415 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3435 |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Park JW et al. (2004) Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A 101: 15974-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Koken MH et al. (1992) Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3. Nucleic Acids Res 20: 5541-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Mounkes LC et al. (1992) A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene. Cell 71: 925-37 PubMed GONUTS page
- ↑ Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
- ↑ 5.0 5.1 Austin RJ & Biggin MD (1996) Purification of the Drosophila RNA polymerase II general transcription factors. Proc Natl Acad Sci U S A 93: 5788-92 PubMed GONUTS page
- ↑ Fregoso M et al. (2007) DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility. Mol Cell Biol 27: 3640-50 PubMed GONUTS page
- ↑ Aguilar-Fuentes J et al. (2008) p8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model. PLoS Genet 4: e1000253 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Aoyagi N & Wassarman DA (2000) Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. J Cell Biol 150: F45-50 PubMed GONUTS page
- ↑ Gutiérrez L et al. (2004) RNA polymerase II 140wimp mutant and mutations in the TFIIH subunit XPB differentially affect homeotic gene expression in Drosophila. Genesis 40: 58-66 PubMed GONUTS page
