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FB:h
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | h ( synonyms: 8247, CG6494, H, HRY, Hairy, bHLHb39, bHLHc14, barrel, brr, dDr1, hry, l(3)08247, l(3)rM384 ) | |
| Protein Name(s) | hairy, | |
| External Links | ||
| FB | FBgn0001168 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0076513 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0107533 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0107533 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001139 |
P |
From FB |
||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0123593 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0131266 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000902 |
cell morphogenesis |
FB:FBrf0155504 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000978 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
FB:FBrf0076513 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001078 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription |
FB:FBrf0076513 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001666 |
response to hypoxia |
FB:FBrf0205954 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0107533 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001139 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0107533 |
IPI: Inferred from Physical Interaction |
FB:FBgn0020496 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0123593 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007366 |
periodic partitioning by pair rule gene |
FB:FBrf0123593 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007366 |
periodic partitioning by pair rule gene |
FB:FBrf0125812 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007366 |
periodic partitioning by pair rule gene |
FB:FBrf0158726 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007366 |
periodic partitioning by pair rule gene |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0161619 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0187390 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007431 |
salivary gland development |
FB:FBrf0158826 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007431 |
salivary gland development |
FB:FBrf0168046 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0155504 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261434 |
P |
From FB |
||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0155504 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0159337 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007460 |
R8 cell fate commitment |
FB:FBrf0144824 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0109791 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001139 |
F |
From FB |
||
| GO:0008407 |
chaeta morphogenesis |
FB:FBrf0123593 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016044 |
cellular membrane organization |
FB:FBrf0158826 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031323 |
regulation of cellular metabolic process |
FB:FBrf0205954 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035239 |
tube morphogenesis |
FB:FBrf0155504 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035289 |
posterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035290 |
trunk segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0076138 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0141797 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0151319 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0070888 |
E-box binding |
FB:FBrf0076513 |
IDA: Inferred from Direct Assay |
F |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Van Doren M et al. (1994) Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev 8: 2729-42 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Zhang H & Levine M (1999) Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo. Proc Natl Acad Sci U S A 96: 535-40 PubMed GONUTS page
- ↑ Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Myat MM & Andrew DJ (2002) Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane. Cell 111: 879-91 PubMed GONUTS page
- ↑ 5.0 5.1 Zhou D et al. (2008) Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch. PLoS Genet 4: e1000221 PubMed GONUTS page
- ↑ Davis GK & Patel NH (1999) The origin and evolution of segmentation. Trends Cell Biol 9: M68-72 PubMed GONUTS page
- ↑ Davis GK & Patel NH (2003) Playing by pair-rules? Bioessays 25: 425-9 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
- ↑ Myat MM et al. (2005) A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea. Dev Biol 281: 38-52 PubMed GONUTS page
- ↑ 10.0 10.1 Sudarsan V (2003) Tube morphogenesis: no pipe dream in Drosophila. Curr Biol 13: R131-3 PubMed GONUTS page
- ↑ Nelson WJ (2003) Tube morphogenesis: closure, but many openings remain. Trends Cell Biol 13: 615-21 PubMed GONUTS page
- ↑ Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
- ↑ Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
- ↑ Goldstein RE et al. (1999) Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho. Development 126: 3747-55 PubMed GONUTS page
- ↑ Tsai C & Gergen P (1995) Pair-rule expression of the Drosophila fushi tarazu gene: a nuclear receptor response element mediates the opposing regulatory effects of runt and hairy. Development 121: 453-62 PubMed GONUTS page
- ↑ Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page
- ↑ Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page