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FB:gw

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) gw ( synonyms: CG11484, CG31992, CG9905, GW182, Gawki, Gawky, Gw, anon-EST:Posey205, dGW182 )
Protein Name(s) gawky,
External Links
FB FBgn0051992

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012677

F

From FB

GO:0000932

cytoplasmic mRNA processing body

FB:FBrf0194369
PMID:16880270[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0000932

cytoplasmic mRNA processing body

FB:FBrf0200920
PMID:17403906[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0001700

embryonic development via the syncytial blastoderm

FB:FBrf0194369
PMID:16880270[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000504

F

From FB

GO:0006402

mRNA catabolic process

FB:FBrf0194513
PMID:16815998[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035195

gene silencing by miRNA

FB:FBrf0190594
PMID:16177138[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035195

gene silencing by miRNA

FB:FBrf0194513
PMID:16815998[3]

IMP: Inferred from Mutant Phenotype

P

From FB

NOT

GO:0000184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

FB:FBrf0190594
PMID:16177138[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Schneider MD et al. (2006) Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development. J Cell Biol 174: 349-58 PubMed GONUTS page
  2. Eulalio A et al. (2007) P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 27: 3970-81 PubMed GONUTS page
  3. 3.0 3.1 Behm-Ansmant I et al. (2006) mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev 20: 1885-98 PubMed GONUTS page
  4. 4.0 4.1 Rehwinkel J et al. (2005) A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA 11: 1640-7 PubMed GONUTS page
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