![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:gt
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | gt ( synonyms: CG7952, EG:BACH7M4.5, GIAN_DROME, GT, Giant, Gt, l(1)3Aa, l(1)giant ) | |
| Protein Name(s) | giant, | |
| External Links | ||
| FB | FBgn0001150 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0055919 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0125319 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0141797 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0156773 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
FB:FBrf0055919 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0000980 |
RNA polymerase II distal enhancer sequence-specific DNA binding |
FB:FBrf0125319 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0156773 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0205197 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
FB:FBrf0125319 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0055919 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0156773 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007354 |
zygotic determination of anterior/posterior axis, embryo |
FB:FBrf0141797 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007354 |
zygotic determination of anterior/posterior axis, embryo |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007362 |
terminal region determination |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0007381 |
specification of segmental identity, labial segment |
FB:FBrf0204829 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0212090 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007431 |
salivary gland development |
FB:FBrf0139594 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0008361 |
regulation of cell size |
FB:FBrf0212090 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010468 |
regulation of gene expression |
FB:FBrf0055919 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035271 |
ring gland development |
FB:FBrf0179777 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035271 |
ring gland development |
FB:FBrf0212090 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035289 |
posterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040015 |
negative regulation of multicellular organism growth |
FB:FBrf0208858 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042803 |
protein homodimerization activity |
FB:FBrf0152056 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0055919 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0044324 |
regulation of transcription involved in anterior/posterior axis specification |
FB:FBrf0125319 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0152056 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0046983 |
protein dimerization activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Capovilla M et al. (1992) The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other segmentation gap genes. Development 114: 99-112 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Shimell MJ et al. (2000) Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene. Dev Biol 218: 38-52 PubMed GONUTS page
- ↑ 3.0 3.1 Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page
- ↑ Li XY et al. (2008) Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. PLoS Biol 6: e27 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 6.0 6.1 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
- ↑ 7.0 7.1 Strecker TR et al. (1991) Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo. Proc Natl Acad Sci U S A 88: 5824-8 PubMed GONUTS page
- ↑ Sanders LR et al. (2008) The Drosophila gap gene giant has an anterior segment identity function mediated through disconnected and teashirt. Genetics 179: 441-53 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Ghosh A et al. (2010) The Drosophila gap gene giant regulates ecdysone production through specification of the PTTH-producing neurons. Dev Biol 347: 271-8 PubMed GONUTS page
- ↑ Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
- ↑ De Velasco B et al. (2004) Embryonic development of the Drosophila corpus cardiacum, a neuroendocrine gland with similarity to the vertebrate pituitary, is controlled by sine oculis and glass. Dev Biol 274: 280-94 PubMed GONUTS page
- ↑ Parrish JZ et al. (2009) The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron 63: 788-802 PubMed GONUTS page
- ↑ 13.0 13.1 Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page