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FB:gro
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | gro ( synonyms: BEST:GM01575, BEST:LD15161, BcDNA.LD33829, BcDNA:LD33829, CG8384, DGro, Dgroucho, E(spl)-WD, E(spl)(2), E(spl)gro, E(spl)m9/m10, En-spl, GRO, Grg/TLE, Gro, Groucho, anon-WO0118547.385, dAES1, dAES2, dGro, l(3)gro, m10, m9, m9,m10, m9-m10, m9/10, m9/m10 ) | |
| Protein Name(s) | groucho, | |
| External Links | ||
| FB | FBgn0001139 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0107533 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001168 |
P |
From FB |
||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0125416 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0131266 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001106 |
RNA polymerase II transcription corepressor activity |
FB:FBrf0155707 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002633 |
F |
From FB |
||
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0108233 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001168 |
F |
From FB |
||
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0123624 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0125416 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0131266 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0141797 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0107533 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001168 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0151266 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004858 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0200831 |
IPI: Inferred from Physical Interaction |
FB:FBgn0262656 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0123624 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0129916 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0056226 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0123624 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007541 |
sex determination, primary response to X:A ratio |
FB:FBrf0125416 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0105336 |
IPI: Inferred from Physical Interaction |
FB:FBgn0260632 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0109791 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001168 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0109791 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002633 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0190132 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003460 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0207814 |
IPI: Inferred from Physical Interaction |
FB:FBgn0040318 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0212975 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
FB:FBrf0151280 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0043234 |
protein complex |
FB:FBrf0200831 |
IPI: Inferred from Physical Interaction |
FB:FBgn0262656 |
C |
From FB |
||
| GO:0045879 |
negative regulation of smoothened signaling pathway |
FB:FBrf0200898 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0123624 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0141797 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0200831 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0262656 |
P |
From FB |
||
| GO:0046331 |
lateral inhibition |
FB:FBrf0214518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0105336 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004795 |
F |
From FB |
||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0109791 |
IPI: Inferred from Physical Interaction |
FB:FBgn0261434 |
F |
From FB |
||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0125241 |
IPI: Inferred from Physical Interaction |
FB:FBgn0262582 |
F |
From FB |
||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0155707 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002633 |
F |
From FB |
||
|
NOT |
GO:0003677 |
DNA binding |
FB:FBrf0141797 |
NAS: Non-traceable Author Statement |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Zhang H & Levine M (1999) Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo. Proc Natl Acad Sci U S A 96: 535-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Schütt C & Nöthiger R (2000) Structure, function and evolution of sex-determining systems in Dipteran insects. Development 127: 667-77 PubMed GONUTS page
- ↑ 3.0 3.1 Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ 4.0 4.1 Giagtzoglou N et al. (2003) Two modes of recruitment of E(spl) repressors onto target genes. Development 130: 259-70 PubMed GONUTS page
- ↑ Mannervik M et al. (1999) Transcriptional coregulators in development. Science 284: 606-9 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page
- ↑ Dorfman R et al. (2002) Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches. Development 129: 3585-96 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Orian A et al. (2007) A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development. Proc Natl Acad Sci U S A 104: 15771-6 PubMed GONUTS page
- ↑ Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
- ↑ Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Schrons H et al. (1992) The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics 132: 481-503 PubMed GONUTS page
- ↑ 12.0 12.1 Valentine SA et al. (1998) Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer. Mol Cell Biol 18: 6584-94 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Goldstein RE et al. (1999) Huckebein repressor activity in Drosophila terminal patterning is mediated by Groucho. Development 126: 3747-55 PubMed GONUTS page
- ↑ Kenyon KL et al. (2005) Partner specificity is essential for proper function of the SIX-type homeodomain proteins Sine oculis and Optix during fly eye development. Dev Biol 286: 158-68 PubMed GONUTS page
- ↑ Syu LJ et al. (2009) The Drosophila Nkx6 homeodomain protein has both activation and repression domains and can activate target gene expression. Brain Res 1266: 8-17 PubMed GONUTS page
- ↑ Ajuria L et al. (2011) Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila. Development 138: 915-24 PubMed GONUTS page
- ↑ Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ Bejarano F et al. (2007) Hedgehog restricts its expression domain in the Drosophila wing. EMBO Rep 8: 778-83 PubMed GONUTS page
- ↑ Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
- ↑ Jiménez G et al. (2000) Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning. Genes Dev 14: 224-31 PubMed GONUTS page
