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FB:grim
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | grim ( synonyms: BcDNA:RE28551, CG4345, GRIM, Grim, gri, grm ) | |
| Protein Name(s) | grim, | |
| External Links | ||
| FB | FBgn0015946 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0133206 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0167429 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0105796 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005739 |
mitochondrion |
FB:FBrf0105796 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0089615 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0089615 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0111320 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0128885 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0157341 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006917 |
induction of apoptosis |
FB:FBrf0111320 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006917 |
induction of apoptosis |
FB:FBrf0111512 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010501 |
P |
From FB |
||
| GO:0006917 |
induction of apoptosis |
FB:FBrf0111512 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0260635 |
P |
From FB |
||
| GO:0006917 |
induction of apoptosis |
FB:FBrf0124324 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006917 |
induction of apoptosis |
FB:FBrf0167429 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0189997 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008627 |
induction of apoptosis by ionic changes |
FB:FBrf0104836 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0012501 |
programmed cell death |
FB:FBrf0147184 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0012501 |
programmed cell death |
FB:FBrf0149068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016567 |
protein ubiquitination |
FB:FBrf0167429 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0156082 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030162 |
regulation of proteolysis |
FB:FBrf0167429 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035006 |
melanization defense response |
FB:FBrf0192653 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035193 |
larval central nervous system remodeling |
FB:FBrf0128665 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0043068 |
positive regulation of programmed cell death |
FB:FBrf0212047 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043524 |
negative regulation of neuron apoptotic process |
FB:FBrf0213685 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
NOT |
GO:0045476 |
nurse cell apoptotic process |
FB:FBrf0132269 |
TAS: Traceable Author Statement |
P |
From FB |
||
|
NOT |
GO:0045476 |
nurse cell apoptotic process |
FB:FBrf0149068 |
TAS: Traceable Author Statement |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Buszczak M & Segraves WA (2000) Insect metamorphosis: out with the old, in with the new. Curr Biol 10: R830-3 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Bergmann A et al. (2003) Regulators of IAP function: coming to grips with the grim reaper. Curr Opin Cell Biol 15: 717-24 PubMed GONUTS page
- ↑ 3.0 3.1 Clavería C et al. (1998) Drosophila grim induces apoptosis in mammalian cells. EMBO J 17: 7199-208 PubMed GONUTS page
- ↑ 4.0 4.1 Chen P et al. (1996) grim, a novel cell death gene in Drosophila. Genes Dev 10: 1773-82 PubMed GONUTS page
- ↑ 5.0 5.1 Abrams JM (1999) An emerging blueprint for apoptosis in Drosophila. Trends Cell Biol 9: 435-40 PubMed GONUTS page
- ↑ De Laurenzi V & Melino G (2000) Apoptosis. The little devil of death. Nature 406: 135-6 PubMed GONUTS page
- ↑ 7.0 7.1 Wang SL et al. (1999) The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98: 453-63 PubMed GONUTS page
- ↑ Bauer JH et al. (2005) Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span. Curr Biol 15: 2063-8 PubMed GONUTS page
- ↑ Avdonin V et al. (1998) Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels. Proc Natl Acad Sci U S A 95: 11703-8 PubMed GONUTS page
- ↑ Gorski S & Marra M (2002) Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiol Genomics 9: 59-69 PubMed GONUTS page
- ↑ 11.0 11.1 Richardson H & Kumar S (2002) Death to flies: Drosophila as a model system to study programmed cell death. J Immunol Methods 265: 21-38 PubMed GONUTS page
- ↑ Ditzel M & Meier P (2002) IAP degradation: decisive blow or altruistic sacrifice? Trends Cell Biol 12: 449-52 PubMed GONUTS page
- ↑ Bidla G et al. (2007) Crystal cell rupture after injury in Drosophila requires the JNK pathway, small GTPases and the TNF homolog Eiger. J Cell Sci 120: 1209-15 PubMed GONUTS page
- ↑ Tissot M & Stocker RF (2000) Metamorphosis in drosophila and other insects: the fate of neurons throughout the stages. Prog Neurobiol 62: 89-111 PubMed GONUTS page
- ↑ Wu JN et al. (2010) grim promotes programmed cell death of Drosophila microchaete glial cells. Mech Dev 127: 407-17 PubMed GONUTS page
- ↑ Tan Y et al. (2011) Coordinated expression of cell death genes regulates neuroblast apoptosis. Development 138: 2197-206 PubMed GONUTS page
- ↑ Buszczak M & Cooley L (2000) Eggs to die for: cell death during Drosophila oogenesis. Cell Death Differ 7: 1071-4 PubMed GONUTS page
