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FB:grh
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | grh ( synonyms: BcDNA:LD38807, CG30111, CG42311, CG5058, DREB, EG:191D12.1, Element I binding activity, Elf-1, Elf-1/NTF-1, Elf1, GRH, Gh, Grainy head, Grainyhead, Grh, NTF, NTF-1, NTF-1/Elf-1, NTF1, Neurogenic element binding transcription factor, Ntf, Ntf1, decapentaplegic repression element binding protein, elf1, elf1(CAG)((7)), grainyhead, head skeleton, hsk, l(2)06850, l(2)IM45, l(2)s2140, neuronal transcription factor 1, ntf-1 ) | |
| Protein Name(s) | grainy head, | |
| External Links | ||
| FB | FBgn0259211 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003382 |
epithelial cell morphogenesis |
FB:FBrf0203016 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0074675 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0085458 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0085458 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123560 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0211626 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
FB:FBrf0123560 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007009 |
plasma membrane organization |
FB:FBrf0155706 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0187453 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007402 |
ganglion mother cell fate determination |
FB:FBrf0158840 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007419 |
ventral cord development |
FB:FBrf0158840 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0155706 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0158826 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007426 |
tracheal outgrowth, open tracheal system |
FB:FBrf0155706 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007428 |
primary branching, open tracheal system |
FB:FBrf0161023 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007464 |
R3/R4 cell fate commitment |
FB:FBrf0213000 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0155706 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008362 |
chitin-based embryonic cuticle biosynthetic process |
FB:FBrf0149011 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016044 |
cellular membrane organization |
FB:FBrf0158826 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035152 |
regulation of tube architecture, open tracheal system |
FB:FBrf0161023 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035152 |
regulation of tube architecture, open tracheal system |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035159 |
regulation of tube length, open tracheal system |
FB:FBrf0155706 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040003 |
chitin-based cuticle development |
FB:FBrf0214191 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042127 |
regulation of cell proliferation |
FB:FBrf0187453 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042803 |
protein homodimerization activity |
FB:FBrf0211626 |
IPI: Inferred from Physical Interaction |
FB:FBgn0259211 |
F |
From FB |
||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0211626 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0108816 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0061041 |
regulation of wound healing |
FB:FBrf0214191 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Narasimha M et al. (2008) Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis. J Cell Sci 121: 747-52 PubMed GONUTS page
- ↑ Uv AE et al. (1994) The Drosophila tissue-specific factor Grainyhead contains novel DNA-binding and dimerization domains which are conserved in the human protein CP2. Mol Cell Biol 14: 4020-31 PubMed GONUTS page
- ↑ 3.0 3.1 Liaw GJ et al. (1995) The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes Dev 9: 3163-76 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Harrison MM et al. (2010) Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes. Dev Biol 345: 248-55 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Hemphälä J et al. (2003) Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling. Development 130: 249-58 PubMed GONUTS page
- ↑ 6.0 6.1 Cenci C & Gould AP (2005) Drosophila Grainyhead specifies late programmes of neural proliferation by regulating the mitotic activity and Hox-dependent apoptosis of neuroblasts. Development 132: 3835-45 PubMed GONUTS page
- ↑ 7.0 7.1 Skeath JB & Thor S (2003) Genetic control of Drosophila nerve cord development. Curr Opin Neurobiol 13: 8-15 PubMed GONUTS page
- ↑ 8.0 8.1 Sudarsan V (2003) Tube morphogenesis: no pipe dream in Drosophila. Curr Biol 13: R131-3 PubMed GONUTS page
- ↑ 9.0 9.1 Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ 10.0 10.1 Uv A et al. (2003) Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems. Trends Cell Biol 13: 301-9 PubMed GONUTS page
- ↑ Gambis A et al. (2011) Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila. Dev Biol 351: 128-34 PubMed GONUTS page
- ↑ Ostrowski S et al. (2002) Genetic control of cuticle formation during embryonic development of Drosophila melanogaster. Genetics 161: 171-82 PubMed GONUTS page
- ↑ 13.0 13.1 Kim M & McGinnis W (2011) Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier. Proc Natl Acad Sci U S A 108: 650-5 PubMed GONUTS page
- ↑ Jennings BH et al. (1999) Target specificities of Drosophila enhancer of split basic helix-loop-helix proteins. Mol Cell Biol 19: 4600-10 PubMed GONUTS page
