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FB:gd

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) gd ( synonyms: CG1505, GD, Gastrulation Defective, SP186, fs(1)18, fs(1)190-5, fs(1)573, fs(1)A573, fs(1)M18, fs(1)gd, gas, gastrulation defective )
Protein Name(s) gastrulation-defective,
External Links
FB FBgn0000808

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004252

serine-type endopeptidase activity

FB:FBrf0102954
PMID:9618496[1]

ISS: Inferred from Sequence or Structural Similarity

HGNC:3551

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0117718

NAS: Non-traceable Author Statement

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0129769
PMID:10961941[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0136636

NAS: Non-traceable Author Statement

F

From FB

GO:0005576

extracellular region

FB:FBrf0102954
PMID:9618496[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005576

extracellular region

FB:FBrf0136636

NAS: Non-traceable Author Statement

C

From FB

GO:0006508

proteolysis

FB:FBrf0141281
PMID:11700289[3]

TAS: Traceable Author Statement

P

From FB

GO:0006508

proteolysis

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001254

P

From FB

GO:0007311

maternal specification of dorsal/ventral axis, oocyte, germ-line encoded

FB:FBrf0055883
PMID:1425342[4]

TAS: Traceable Author Statement

P

From FB

GO:0007311

maternal specification of dorsal/ventral axis, oocyte, germ-line encoded

FB:FBrf0110978
PMID:10449356[5]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0055562
PMID:1739964[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0003089

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0055562
PMID:1739964[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0262473

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0055883
PMID:1425342[4]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0141068
PMID:11283698[7]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0141086
PMID:11135568[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0008233

peptidase activity

FB:FBrf0141281
PMID:11700289[3]

TAS: Traceable Author Statement

F

From FB

GO:0008236

serine-type peptidase activity

FB:FBrf0110978
PMID:10449356[5]

NAS: Non-traceable Author Statement

F

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0055562
PMID:1739964[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0127230
PMID:10793472[9]

TAS: Traceable Author Statement

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0141281
PMID:11700289[3]

TAS: Traceable Author Statement

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0208501
PMID:19540119[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0003089

P

From FB

GO:0016485

protein processing

FB:FBrf0055883
PMID:1425342[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0000533

P

From FB

NOT

GO:0004252

serine-type endopeptidase activity

FB:FBrf0155784
PMID:12568721[11]

NAS: Non-traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Konrad KD et al. (1998) The gastrulation defective gene of Drosophila melanogaster is a member of the serine protease superfamily. Proc Natl Acad Sci U S A 95: 6819-24 PubMed GONUTS page
  2. Coates D et al. (2000) Exploring the Caenorhabditis elegans and Drosophila melanogaster genomes to understand neuropeptide and peptidase function. Biochem Soc Trans 28: 464-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 Lall S & Patel NH (2001) Conservation and divergence in molecular mechanisms of axis formation. Annu Rev Genet 35: 407-37 PubMed GONUTS page
  4. 4.0 4.1 4.2 Chasan R et al. (1992) Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo. Development 115: 607-16 PubMed GONUTS page
  5. 5.0 5.1 van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
  6. 6.0 6.1 6.2 Stein D & Nüsslein-Volhard C (1992) Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity. Cell 68: 429-40 PubMed GONUTS page
  7. Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
  8. Beutler B & Poltorak A (2001) Toll we meet again.... Nat Immunol 2: 9-10 PubMed GONUTS page
  9. Meister M et al. (2000) The antimicrobial host defense of Drosophila. Curr Top Microbiol Immunol 248: 17-36 PubMed GONUTS page
  10. Zhang Z et al. (2009) Sulfation of eggshell components by Pipe defines dorsal-ventral polarity in the Drosophila embryo. Curr Biol 19: 1200-5 PubMed GONUTS page
  11. Ross J et al. (2003) Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 304: 117-31 PubMed GONUTS page
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