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FB:gcm
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | gcm ( synonyms: CG12245, GCM, GCM1, Gcm, Glial Cell Missing, N7-4, glia cells missing, glial cell deficient, glial cell missing, glial cells-missing, glide, glide glide2, glide/gcm, l(2)N7-4, ucc, upper class chordotonals ) | |
| Protein Name(s) | glial cells missing, | |
| External Links | ||
| FB | FBgn0014179 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
FB:FBrf0090430 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0151252 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0084071 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0151252 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007403 |
glial cell fate determination |
FB:FBrf0084044 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007403 |
glial cell fate determination |
FB:FBrf0130132 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007403 |
glial cell fate determination |
FB:FBrf0135724 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0131266 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0144845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008283 |
cell proliferation |
FB:FBrf0151252 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010001 |
glial cell differentiation |
FB:FBrf0084071 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010001 |
glial cell differentiation |
FB:FBrf0138381 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0019809 |
P |
From FB |
||
| GO:0010001 |
glial cell differentiation |
FB:FBrf0138381 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010001 |
glial cell differentiation |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0010001 |
glial cell differentiation |
FB:FBrf0190357 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010628 |
positive regulation of gene expression |
FB:FBrf0204114 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0021782 |
glial cell development |
FB:FBrf0191311 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030182 |
neuron differentiation |
FB:FBrf0191311 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031290 |
retinal ganglion cell axon guidance |
FB:FBrf0187493 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035164 |
embryonic plasmatocyte differentiation |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035165 |
embryonic crystal cell differentiation |
FB:FBrf0187450 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035169 |
lymph gland plasmatocyte differentiation |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042063 |
gliogenesis |
FB:FBrf0138381 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0019809 |
P |
From FB |
||
| GO:0042063 |
gliogenesis |
FB:FBrf0138381 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042063 |
gliogenesis |
FB:FBrf0201091 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042387 |
plasmatocyte differentiation |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0042387 |
plasmatocyte differentiation |
FB:FBrf0151252 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042387 |
plasmatocyte differentiation |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042387 |
plasmatocyte differentiation |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042690 |
negative regulation of crystal cell differentiation |
FB:FBrf0187450 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045610 |
regulation of hemocyte differentiation |
FB:FBrf0208351 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045687 |
positive regulation of glial cell differentiation |
FB:FBrf0214495 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0084071 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0159339 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0060252 |
positive regulation of glial cell proliferation |
FB:FBrf0208044 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0060857 |
establishment of glial blood-brain barrier |
FB:FBrf0202685 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
NOT |
GO:0042688 |
crystal cell differentiation |
FB:FBrf0151252 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Akiyama Y et al. (1996) The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. Proc Natl Acad Sci U S A 93: 14912-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Alfonso TB & Jones BW (2002) gcm2 promotes glial cell differentiation and is required with glial cells missing for macrophage development in Drosophila. Dev Biol 248: 369-83 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Jones BW et al. (1995) glial cells missing: a genetic switch that controls glial versus neuronal fate. Cell 82: 1013-23 PubMed GONUTS page
- ↑ Hosoya T et al. (1995) glial cells missing: a binary switch between neuronal and glial determination in Drosophila. Cell 82: 1025-36 PubMed GONUTS page
- ↑ Van De Bor V et al. (2000) Some fly sensory organs are gliogenic and require glide/gcm in a precursor that divides symmetrically and produces glial cells. Development 127: 3735-43 PubMed GONUTS page
- ↑ Udolph G et al. (2001) A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-66 PubMed GONUTS page
- ↑ Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ Fossett N & Schulz RA (2001) Functional conservation of hematopoietic factors in Drosophila and vertebrates. Differentiation 69: 83-90 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Kammerer M & Giangrande A (2001) Glide2, a second glial promoting factor in Drosophila melanogaster. EMBO J 20: 4664-73 PubMed GONUTS page
- ↑ 10.0 10.1 Evans CJ & Banerjee U (2003) Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol Dis 30: 223-8 PubMed GONUTS page
- ↑ De Iaco R et al. (2006) Huckebein-mediated autoregulation of Glide/Gcm triggers glia specification. EMBO J 25: 244-54 PubMed GONUTS page
- ↑ Mandalaywala NV et al. (2008) The tumor suppressor, vitamin D3 up-regulated protein 1 (VDUP1), functions downstream of REPO during Drosophila gliogenesis. Dev Biol 315: 489-504 PubMed GONUTS page
- ↑ 13.0 13.1 Chotard C et al. (2005) glial cells missing and gcm2 cell autonomously regulate both glial and neuronal development in the visual system of Drosophila. Neuron 48: 237-51 PubMed GONUTS page
- ↑ Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Yoshida S et al. (2005) DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila. Development 132: 4587-98 PubMed GONUTS page
- ↑ 16.0 16.1 Meister M (2004) Blood cells of Drosophila: cell lineages and role in host defence. Curr Opin Immunol 16: 10-5 PubMed GONUTS page
- ↑ 17.0 17.1 Bataillé L et al. (2005) Resolving embryonic blood cell fate choice in Drosophila: interplay of GCM and RUNX factors. Development 132: 4635-44 PubMed GONUTS page
- ↑ Soustelle L & Giangrande A (2007) Novel gcm-dependent lineages in the postembryonic nervous system of Drosophila melanogaster. Dev Dyn 236: 2101-8 PubMed GONUTS page
- ↑ Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ Jacques C et al. (2009) A novel role of the glial fate determinant glial cells missing in hematopoiesis. Int J Dev Biol 53: 1013-22 PubMed GONUTS page
- ↑ Viktorin G et al. (2011) Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain development. Dev Biol 356: 553-65 PubMed GONUTS page
- ↑ Gao FB & Bogert BA (2003) Genetic control of dendritic morphogenesis in Drosophila. Trends Neurosci 26: 262-8 PubMed GONUTS page
- ↑ Ho MS et al. (2009) Gcm protein degradation suppresses proliferation of glial progenitors. Proc Natl Acad Sci U S A 106: 6778-83 PubMed GONUTS page
- ↑ Stork T et al. (2008) Organization and function of the blood-brain barrier in Drosophila. J Neurosci 28: 587-97 PubMed GONUTS page
