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FB:futsch

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) futsch ( synonyms: 22C10, 22C10/FUTSCH, 22C20, 22c10, CG14772, CG3064, CG34387, EG:49E4.1, FUTSCH, Futch, Futsch, MAP-IB, MAP1B, MAb22C10, Mab 22C10, Mab22C10, Mab22c10, Olk, mAb 22C10, mAb-22C10, mAb22C10, mAb22c10, map1b, olk, omb-like, ssC10 )
Protein Name(s) futsch,
External Links
FB FBgn0259108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000226

microtubule cytoskeleton organization

FB:FBrf0128626
PMID:10839356[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0005515

protein binding

FB:FBrf0141416
PMID:11733059[2]

IPI: Inferred from Physical Interaction

FB:FBgn0028734

F

From FB

GO:0005875

microtubule associated complex

FB:FBrf0071734

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0128497
PMID:10839355[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0128626
PMID:10839356[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0007017

microtubule-based process

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007399

nervous system development

FB:FBrf0156127
PMID:11879765[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0007409

axonogenesis

FB:FBrf0128497
PMID:10839355[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007528

neuromuscular junction development

FB:FBrf0156127
PMID:11879765[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0008017

microtubule binding

FB:FBrf0071734

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008017

microtubule binding

FB:FBrf0128497
PMID:10839355[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0008017

microtubule binding

FB:FBrf0128497
PMID:10839355[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P46821

F

From FB

GO:0008017

microtubule binding

FB:FBrf0128626
PMID:10839356[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0008017

microtubule binding

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008088

axon cargo transport

FB:FBrf0188078
PMID:15772149[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008355

olfactory learning

FB:FBrf0188078
PMID:15772149[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008582

regulation of synaptic growth at neuromuscular junction

FB:FBrf0128626
PMID:10839356[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008582

regulation of synaptic growth at neuromuscular junction

FB:FBrf0179211
PMID:15269269[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015630

microtubule cytoskeleton

FB:FBrf0128497
PMID:10839355[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0043524

negative regulation of neuron apoptotic process

FB:FBrf0188078
PMID:15772149[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0156127
PMID:11879765[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0128497
PMID:10839355[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0060052

neurofilament cytoskeleton organization

FB:FBrf0188078
PMID:15772149[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Roos J et al. (2000) Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron 26: 371-82 PubMed GONUTS page
  2. Zhang YQ et al. (2001) Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 107: 591-603 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Hummel T et al. (2000) Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron 26: 357-70 PubMed GONUTS page
  4. 4.0 4.1 4.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 Oostra BA (2002) Functions of the fragile X protein. Trends Mol Med 8: 102-3 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Bettencourt da Cruz A et al. (2005) Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Mol Biol Cell 16: 2433-42 PubMed GONUTS page
  7. Franco B et al. (2004) Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J Neurosci 24: 6573-7 PubMed GONUTS page
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