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FB:ftz-f1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ftz-f1 ( synonyms: BFTZ-F1, CG13378, CG4059, DEP1, DmFTZ-F1, FIP1, FTZ-F1, FTZ-F1alpha, FTZF1, FTZf1alpha, Ftz interacting protein 1, Ftz-F1, Ftz-f1, NR5A3, alphaFTZ-F1, alphaFTZF1, alphaftz-f1, bFTZ-F1, beta FTZ-F1, beta Ftz-f1, beta-FTZ-F1, beta-Ftz transcription factor 1, beta-Ftz-F1, betaFTZ-F1, betaFTZF1, betaFtz-F1, betaFtz-f1, betaftz-F1, betaftz-f1, dFTZ-F1alpha, dFtz-F1alpha, ftz factor 1, ftz-F1, ftz-f1alpha, ftz-transcription factor 1, ftzf1, l(3)03649 )
Protein Name(s) ftz transcription factor 1,
External Links
FB FBgn0001078

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000976

transcription regulatory region sequence-specific DNA binding

FB:FBrf0215576
PMID:21832074[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

FB:FBrf0074064
PMID:8164672[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0002165

instar larval or pupal development

FB:FBrf0158854
PMID:12710964[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0057244
PMID:1732738[4]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0156739

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O00482

F

From FB

GO:0003707

steroid hormone receptor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000536
InterPro:IPR001723
InterPro:IPR008946

F

From FB

GO:0003712

transcription cofactor activity

FB:FBrf0156739

NAS: Non-traceable Author Statement

F

From FB

GO:0004879

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O00482

F

From FB

GO:0004879

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0138424
PMID:11532213[5]

NAS: Non-traceable Author Statement

F

From FB

GO:0004879

ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0156739

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0057244
PMID:1732738[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O00482

C

From FB

GO:0005634

nucleus

FB:FBrf0156739

NAS: Non-traceable Author Statement

C

From FB

GO:0005737

cytoplasm

FB:FBrf0157336
PMID:12655640[6]

NAS: Non-traceable Author Statement

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0156739

NAS: Non-traceable Author Statement

P

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0109169
PMID:10381570[7]

IDA: Inferred from Direct Assay

P

From FB

GO:0007365

periodic partitioning

FB:FBrf0091142
PMID:8978055[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007480

imaginal disc-derived leg morphogenesis

FB:FBrf0212489
PMID:21145504[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007552

metamorphosis

FB:FBrf0141454
PMID:11703937[10]

TAS: Traceable Author Statement

P

From FB

GO:0007552

metamorphosis

FB:FBrf0212489
PMID:21145504[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008134

transcription factor binding

FB:FBrf0215576
PMID:21832074[1]

IPI: Inferred from Physical Interaction

FB:FBgn0002723

F

From FB

GO:0008134

transcription factor binding

FB:FBrf0215576
PMID:21832074[1]

IPI: Inferred from Physical Interaction

FB:FBgn0261703

F

From FB

GO:0008219

cell death

FB:FBrf0137172
PMID:11494315[11]

TAS: Traceable Author Statement

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001628
InterPro:IPR013088

F

From FB

GO:0009725

response to hormone stimulus

FB:FBrf0137172
PMID:11494315[11]

TAS: Traceable Author Statement

P

From FB

GO:0035071

salivary gland cell autophagic cell death

FB:FBrf0126529

NAS: Non-traceable Author Statement

P

From FB

GO:0035074

pupation

FB:FBrf0212489
PMID:21145504[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035075

response to ecdysone

FB:FBrf0128149
PMID:10882130[12]

TAS: Traceable Author Statement

P

From FB

GO:0035626

juvenile hormone mediated signaling pathway

FB:FBrf0215576
PMID:21832074[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0040034

regulation of development, heterochronic

FB:FBrf0141454
PMID:11703937[10]

TAS: Traceable Author Statement

P

From FB

GO:0042048

olfactory behavior

FB:FBrf0192106
PMID:17028343[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043401

steroid hormone mediated signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000536
InterPro:IPR008946

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0215576
PMID:21832074[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0215576
PMID:21832074[1]

IPI: Inferred from Physical Interaction

FB:FBgn0002723

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0215576
PMID:21832074[1]

IPI: Inferred from Physical Interaction

FB:FBgn0261703

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Dubrovsky EB et al. (2011) The Drosophila FTZ-F1 nuclear receptor mediates juvenile hormone activation of E75A gene expression through an intracellular pathway. J Biol Chem 286: 33689-700 PubMed GONUTS page
  2. Ohno CK et al. (1994) The Drosophila nuclear receptors FTZ-F1 alpha and FTZ-F1 beta compete as monomers for binding to a site in the fushi tarazu gene. Mol Cell Biol 14: 3166-75 PubMed GONUTS page
  3. Fortier TM et al. (2003) Orphan nuclear receptor betaFTZ-F1 is required for muscle-driven morphogenetic events at the prepupal-pupal transition in Drosophila melanogaster. Dev Biol 257: 153-65 PubMed GONUTS page
  4. 4.0 4.1 Ayer S & Benyajati C (1992) The binding site of a steroid hormone receptor-like protein within the Drosophila Adh adult enhancer is required for high levels of tissue-specific alcohol dehydrogenase expression. Mol Cell Biol 12: 661-73 PubMed GONUTS page
  5. Maglich JM et al. (2001) Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol 2: RESEARCH0029 PubMed GONUTS page
  6. Leatherman JL & Jongens TA (2003) Transcriptional silencing and translational control: key features of early germline development. Bioessays 25: 326-35 PubMed GONUTS page
  7. Yu Y et al. (1999) A double interaction screen identifies positive and negative ftz gene regulators and ftz-interacting proteins. Mech Dev 83: 95-105 PubMed GONUTS page
  8. Perrimon N et al. (1996) Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics 144: 1681-92 PubMed GONUTS page
  9. 9.0 9.1 9.2 Rewitz KF et al. (2010) Steroid hormone inactivation is required during the juvenile-adult transition in Drosophila. Dev Cell 19: 895-902 PubMed GONUTS page
  10. 10.0 10.1 Thummel CS (2001) Molecular mechanisms of developmental timing in C. elegans and Drosophila. Dev Cell 1: 453-65 PubMed GONUTS page
  11. 11.0 11.1 Thummel CS (2001) Steroid-triggered death by autophagy. Bioessays 23: 677-82 PubMed GONUTS page
  12. Jiang C et al. (2000) A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Mol Cell 5: 445-55 PubMed GONUTS page
  13. Sambandan D et al. (2006) Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics 174: 1349-63 PubMed GONUTS page
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