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FB:fra
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | fra ( synonyms: CG8581, CT24981, DCC, DCC/Frazzled, Fra, Frazzled, Netrin-receptor, deleted in colorectal cancer ) | |
| Protein Name(s) | frazzled, | |
| External Links | ||
| FB | FBgn0011592 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005042 |
netrin receptor activity |
FB:FBrf0108593 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005042 |
netrin receptor activity |
FB:FBrf0121370 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005042 |
netrin receptor activity |
FB:FBrf0121371 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0090650 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2701 |
C |
From FB |
||
| GO:0007411 |
axon guidance |
FB:FBrf0155635 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0159246 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0174512 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0200520 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0207948 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010105 |
P |
From FB |
||
| GO:0007411 |
axon guidance |
FB:FBrf0207948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007432 |
salivary gland boundary specification |
FB:FBrf0187388 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008045 |
motor axon guidance |
FB:FBrf0090650 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008045 |
motor axon guidance |
FB:FBrf0187314 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008045 |
motor axon guidance |
FB:FBrf0200818 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008347 |
glial cell migration |
FB:FBrf0210391 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0016199 |
axon midline choice point recognition |
FB:FBrf0149078 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030424 |
axon |
FB:FBrf0159246 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0030425 |
dendrite |
FB:FBrf0159246 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0043025 |
neuronal cell body |
FB:FBrf0159246 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0174512 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0208790 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070983 |
dendrite guidance |
FB:FBrf0159246 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Bashaw GJ & Goodman CS (1999) Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion. Cell 97: 917-26 PubMed GONUTS page
- ↑ 2.0 2.1 Kolodziej PA et al. (1996) frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance. Cell 87: 197-204 PubMed GONUTS page
- ↑ Patel BN & Van Vactor DL (2002) Axon guidance: the cytoplasmic tail. Curr Opin Cell Biol 14: 221-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Furrer MP et al. (2003) Robo and Frazzled/DCC mediate dendritic guidance at the CNS midline. Nat Neurosci 6: 223-30 PubMed GONUTS page
- ↑ 5.0 5.1 Grueber WB & Jan YN (2004) Dendritic development: lessons from Drosophila and related branches. Curr Opin Neurobiol 14: 74-82 PubMed GONUTS page
- ↑ Garbe DS et al. (2007) Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline. Development 134: 4325-34 PubMed GONUTS page
- ↑ 7.0 7.1 Yang L et al. (2009) A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance. Science 324: 944-7 PubMed GONUTS page
- ↑ Kolesnikov T & Beckendorf SK (2005) NETRIN and SLIT guide salivary gland migration. Dev Biol 284: 102-11 PubMed GONUTS page
- ↑ Labrador JP et al. (2005) The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. Curr Biol 15: 1413-9 PubMed GONUTS page
- ↑ Dorsten JN et al. (2007) Frazzled regulation of myosin II activity in the Drosophila embryonic CNS. Dev Biol 308: 120-32 PubMed GONUTS page
- ↑ von Hilchen CM et al. (2010) Netrins guide migration of distinct glial cells in the Drosophila embryo. Development 137: 1251-62 PubMed GONUTS page
- ↑ Ratnaparkhi A et al. (2002) Altered levels of Gq activity modulate axonal pathfinding in Drosophila. J Neurosci 22: 4499-508 PubMed GONUTS page
- ↑ Mauss A et al. (2009) Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system. PLoS Biol 7: e1000200 PubMed GONUTS page
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