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FB:foi

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) foi ( synonyms: CG6817, FOI, dFOI, fear of intimacy, kas, kastchen, l(3)j8E8, l(3)neo13 )
Protein Name(s) fear-of-intimacy,
External Links
FB FBgn0024236

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005385

zinc ion transmembrane transporter activity

FB:FBrf0187794
PMID:15509557[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0005886

plasma membrane

FB:FBrf0158886
PMID:12702650[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0006829

zinc ion transport

FB:FBrf0190307
PMID:16481356[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007280

pole cell migration

FB:FBrf0102832
PMID:9637912[4]

TAS: Traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0108204
PMID:10328928[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0100771
PMID:9435287[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0158886
PMID:12702650[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007506

gonadal mesoderm development

FB:FBrf0162071
PMID:12900457[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008354

germ cell migration

FB:FBrf0100771
PMID:9435287[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008354

germ cell migration

FB:FBrf0180105
PMID:15464587[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008406

gonad development

FB:FBrf0102832
PMID:9637912[4]

TAS: Traceable Author Statement

P

From FB

GO:0008406

gonad development

FB:FBrf0162005
PMID:12956974[9]

TAS: Traceable Author Statement

P

From FB

GO:0009986

cell surface

FB:FBrf0158886
PMID:12702650[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0009986

cell surface

FB:FBrf0190307
PMID:16481356[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0016477

cell migration

FB:FBrf0158886
PMID:12702650[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035147

branch fusion, open tracheal system

FB:FBrf0158886
PMID:12702650[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035262

gonad morphogenesis

FB:FBrf0190307
PMID:16481356[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0055085

transmembrane transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR003689

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Mathews WR et al. (2005) Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J Biol Chem 280: 787-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Van Doren M et al. (2003) fear of intimacy encodes a novel transmembrane protein required for gonad morphogenesis in Drosophila. Development 130: 2355-64 PubMed GONUTS page
  3. 3.0 3.1 3.2 Mathews WR et al. (2006) Zinc transport activity of Fear of Intimacy is essential for proper gonad morphogenesis and DE-cadherin expression. Development 133: 1143-53 PubMed GONUTS page
  4. 4.0 4.1 Howard K (1998) Organogenesis: Drosophila goes gonadal. Curr Biol 8: R415-7 PubMed GONUTS page
  5. Hummel T et al. (1999) Commissure formation in the embryonic CNS of Drosophila. Dev Biol 209: 381-98 PubMed GONUTS page
  6. 6.0 6.1 Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
  7. Jenkins AB et al. (2003) Drosophila E-cadherin is essential for proper germ cell-soma interaction during gonad morphogenesis. Development 130: 4417-26 PubMed GONUTS page
  8. Pielage J et al. (2004) The Drosophila transmembrane protein Fear-of-intimacy controls glial cell migration. Dev Biol 275: 245-57 PubMed GONUTS page
  9. Godt D & Tepass U (2003) Organogenesis: keeping in touch with the germ cells. Curr Biol 13: R683-5 PubMed GONUTS page
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