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FB:en
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | en ( synonyms: 153867_at, Apa, Apigmented abdomen, CG9015, EN, En, EnR, Eng, Engrailed, Engrailed/Invected, Erased, Es, Invected, V, en1, spa2, sparse SGPs 2, spermatheca, spt, transcript group V ) | |
| Protein Name(s) | engrailed, | |
| External Links | ||
| FB | FBgn0000577 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0080369 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000980 |
RNA polymerase II distal enhancer sequence-specific DNA binding |
FB:FBrf0080369 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001078 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription |
FB:FBrf0080369 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0042042 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123347 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0123347 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0125812 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0131266 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0141518 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0158726 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007367 |
segment polarity determination |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007386 |
compartment pattern specification |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007386 |
compartment pattern specification |
FB:FBrf0151319 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007388 |
posterior compartment specification |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007400 |
neuroblast fate determination |
FB:FBrf0093362 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001269 |
P |
From FB |
||
| GO:0007400 |
neuroblast fate determination |
FB:FBrf0093362 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001269 |
P |
From FB |
||
| GO:0007411 |
axon guidance |
FB:FBrf0190277 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007417 |
central nervous system development |
FB:FBrf0123347 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007418 |
ventral midline development |
FB:FBrf0190277 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007447 |
imaginal disc pattern formation |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007448 |
anterior/posterior pattern specification, imaginal disc |
FB:FBrf0111421 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007485 |
imaginal disc-derived male genitalia development |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007486 |
imaginal disc-derived female genitalia development |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007487 |
analia development |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008406 |
gonad development |
FB:FBrf0213539 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010629 |
negative regulation of gene expression |
FB:FBrf0211900 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0021960 |
anterior commissure morphogenesis |
FB:FBrf0190277 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035215 |
genital disc development |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035224 |
genital disc anterior/posterior pattern formation |
FB:FBrf0088118 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0035224 |
genital disc anterior/posterior pattern formation |
FB:FBrf0137175 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035277 |
spiracle morphogenesis, open tracheal system |
FB:FBrf0187474 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035288 |
anterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035289 |
posterior head segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035290 |
trunk segmentation |
FB:FBrf0179912 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0123347 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0141797 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0048099 |
anterior/posterior lineage restriction, imaginal disc |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048099 |
anterior/posterior lineage restriction, imaginal disc |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0123139 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048100 |
wing disc anterior/posterior pattern formation |
FB:FBrf0141064 |
TAS: Traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Sanicola M et al. (1995) Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed. Genetics 139: 745-56 PubMed GONUTS page
- ↑ DiNardo S et al. (1985) Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein. Cell 43: 59-69 PubMed GONUTS page
- ↑ Davis GK & Patel NH (1999) The origin and evolution of segmentation. Trends Cell Biol 9: M68-72 PubMed GONUTS page
- ↑ Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
- ↑ Davis GK & Patel NH (2003) Playing by pair-rules? Bioessays 25: 425-9 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Milán M & Cohen SM (2000) Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control? Dev Biol 217: 1-9 PubMed GONUTS page
- ↑ Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
- ↑ 11.0 11.1 Bhat KM & Schedl P (1997) Requirement for engrailed and invected genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis. Development 124: 1675-88 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Bossing T & Brand AH (2006) Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. Development 133: 1001-12 PubMed GONUTS page
- ↑ Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ Marsh JL & Theisen H (1999) Regeneration in insects. Semin Cell Dev Biol 10: 365-75 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 15.3 Sánchez L & Guerrero I (2001) The development of the Drosophila genital disc. Bioessays 23: 698-707 PubMed GONUTS page
- ↑ Weyers JJ et al. (2011) A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol 353: 217-28 PubMed GONUTS page
- ↑ Seibert J & Urbach R (2010) Role of en and novel interactions between msh, ind, and vnd in dorsoventral patterning of the Drosophila brain and ventral nerve cord. Dev Biol 346: 332-45 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ Freeland DE & Kuhn DT (1996) Expression patterns of developmental genes reveal segment and parasegment organization of D. melanogaster genital discs. Mech Dev 56: 61-72 PubMed GONUTS page
- ↑ Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
- ↑ Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page