Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:en

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) en ( synonyms: 153867_at, Apa, Apigmented abdomen, CG9015, EN, En, EnR, Eng, Engrailed, Engrailed/Invected, Erased, Es, Invected, V, en1, spa2, sparse SGPs 2, spermatheca, spt, transcript group V )
Protein Name(s) engrailed,
External Links
FB FBgn0000577

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0080369
PMID:7713429[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000980

RNA polymerase II distal enhancer sequence-specific DNA binding

FB:FBrf0080369
PMID:7713429[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0001078

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

FB:FBrf0080369
PMID:7713429[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q05925

F

From FB

GO:0005634

nucleus

FB:FBrf0042042
PMID:3935318[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0123347

NAS: Non-traceable Author Statement

C

From FB

GO:0007367

segment polarity determination

FB:FBrf0123347

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0125812
PMID:10611687[3]

TAS: Traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0131266
PMID:11105896[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0141518
PMID:11743020[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0158726
PMID:12717812[6]

NAS: Non-traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0179912
PMID:15382142[7]

TAS: Traceable Author Statement

P

From FB

GO:0007386

compartment pattern specification

FB:FBrf0123139
PMID:10625531[8]

TAS: Traceable Author Statement

P

From FB

GO:0007386

compartment pattern specification

FB:FBrf0151319
PMID:12119094[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0007388

posterior compartment specification

FB:FBrf0141064
PMID:11253649[10]

TAS: Traceable Author Statement

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0093362
PMID:9165116[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0001269
FB:FBgn0001148

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0093362
PMID:9165116[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0001269
FB:FBgn0001148
FB:FBgn0003892

P

From FB

GO:0007411

axon guidance

FB:FBrf0190277
PMID:16467357[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007417

central nervous system development

FB:FBrf0123347

NAS: Non-traceable Author Statement

P

From FB

GO:0007418

ventral midline development

FB:FBrf0190277
PMID:16467357[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007447

imaginal disc pattern formation

FB:FBrf0136845
PMID:11377964[13]

TAS: Traceable Author Statement

P

From FB

GO:0007448

anterior/posterior pattern specification, imaginal disc

FB:FBrf0111421
PMID:10497093[14]

TAS: Traceable Author Statement

P

From FB

GO:0007485

imaginal disc-derived male genitalia development

FB:FBrf0137175
PMID:11494318[15]

TAS: Traceable Author Statement

P

From FB

GO:0007486

imaginal disc-derived female genitalia development

FB:FBrf0137175
PMID:11494318[15]

TAS: Traceable Author Statement

P

From FB

GO:0007487

analia development

FB:FBrf0137175
PMID:11494318[15]

TAS: Traceable Author Statement

P

From FB

GO:0008406

gonad development

FB:FBrf0213539
PMID:21377458[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010629

negative regulation of gene expression

FB:FBrf0211900
PMID:20673828[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0021960

anterior commissure morphogenesis

FB:FBrf0190277
PMID:16467357[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035215

genital disc development

FB:FBrf0187379
PMID:15893978[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035224

genital disc anterior/posterior pattern formation

FB:FBrf0088118
PMID:8798147[19]

IEP: Inferred from Expression Pattern

P

From FB

GO:0035224

genital disc anterior/posterior pattern formation

FB:FBrf0137175
PMID:11494318[15]

TAS: Traceable Author Statement

P

From FB

GO:0035277

spiracle morphogenesis, open tracheal system

FB:FBrf0187474
PMID:15930099[20]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035288

anterior head segmentation

FB:FBrf0179912
PMID:15382142[7]

TAS: Traceable Author Statement

P

From FB

GO:0035289

posterior head segmentation

FB:FBrf0179912
PMID:15382142[7]

TAS: Traceable Author Statement

P

From FB

GO:0035290

trunk segmentation

FB:FBrf0179912
PMID:15382142[7]

TAS: Traceable Author Statement

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0123347

NAS: Non-traceable Author Statement

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0141797
PMID:11691830[21]

NAS: Non-traceable Author Statement

P

From FB

GO:0048099

anterior/posterior lineage restriction, imaginal disc

FB:FBrf0123139
PMID:10625531[8]

TAS: Traceable Author Statement

P

From FB

GO:0048099

anterior/posterior lineage restriction, imaginal disc

FB:FBrf0141064
PMID:11253649[10]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0123139
PMID:10625531[8]

TAS: Traceable Author Statement

P

From FB

GO:0048100

wing disc anterior/posterior pattern formation

FB:FBrf0141064
PMID:11253649[10]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Sanicola M et al. (1995) Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed. Genetics 139: 745-56 PubMed GONUTS page
  2. DiNardo S et al. (1985) Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein. Cell 43: 59-69 PubMed GONUTS page
  3. Davis GK & Patel NH (1999) The origin and evolution of segmentation. Trends Cell Biol 9: M68-72 PubMed GONUTS page
  4. Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
  5. Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
  6. Davis GK & Patel NH (2003) Playing by pair-rules? Bioessays 25: 425-9 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Peel A (2004) The evolution of arthropod segmentation mechanisms. Bioessays 26: 1108-16 PubMed GONUTS page
  8. 8.0 8.1 8.2 Milán M & Cohen SM (2000) Subdividing cell populations in the developing limbs of Drosophila: do wing veins and leg segments define units of growth control? Dev Biol 217: 1-9 PubMed GONUTS page
  9. Calleja M et al. (2002) How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila. Gene 292: 1-12 PubMed GONUTS page
  10. 10.0 10.1 10.2 McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
  11. 11.0 11.1 Bhat KM & Schedl P (1997) Requirement for engrailed and invected genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis. Development 124: 1675-88 PubMed GONUTS page
  12. 12.0 12.1 12.2 Bossing T & Brand AH (2006) Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. Development 133: 1001-12 PubMed GONUTS page
  13. Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
  14. Marsh JL & Theisen H (1999) Regeneration in insects. Semin Cell Dev Biol 10: 365-75 PubMed GONUTS page
  15. 15.0 15.1 15.2 15.3 Sánchez L & Guerrero I (2001) The development of the Drosophila genital disc. Bioessays 23: 698-707 PubMed GONUTS page
  16. Weyers JJ et al. (2011) A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol 353: 217-28 PubMed GONUTS page
  17. Seibert J & Urbach R (2010) Role of en and novel interactions between msh, ind, and vnd in dorsoventral patterning of the Drosophila brain and ventral nerve cord. Dev Biol 346: 332-45 PubMed GONUTS page
  18. Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
  19. Freeland DE & Kuhn DT (1996) Expression patterns of developmental genes reveal segment and parasegment organization of D. melanogaster genital discs. Mech Dev 56: 61-72 PubMed GONUTS page
  20. Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
  21. Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox