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FB:ea

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ea ( synonyms: CG4920, EA, Easter, SP24, c-SP24 )
Protein Name(s) easter,
External Links
FB FBgn0000533

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004252

serine-type endopeptidase activity

FB:FBrf0055883
PMID:1425342[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0129769
PMID:10961941[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0133282

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004252

serine-type endopeptidase activity

FB:FBrf0155784
PMID:12568721[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0005576

extracellular region

FB:FBrf0055883
PMID:1425342[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005576

extracellular region

FB:FBrf0123583

NAS: Non-traceable Author Statement

C

From FB

GO:0006508

proteolysis

FB:FBrf0141281
PMID:11700289[4]

TAS: Traceable Author Statement

P

From FB

GO:0006508

proteolysis

FB:FBrf0155784
PMID:12568721[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0006508

proteolysis

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001254
InterPro:IPR001314
InterPro:IPR018114

P

From FB

GO:0006952

defense response

FB:FBrf0133282

NAS: Non-traceable Author Statement

P

From FB

GO:0007311

maternal specification of dorsal/ventral axis, oocyte, germ-line encoded

FB:FBrf0055883
PMID:1425342[1]

TAS: Traceable Author Statement

P

From FB

GO:0007311

maternal specification of dorsal/ventral axis, oocyte, germ-line encoded

FB:FBrf0110978
PMID:10449356[5]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0055883
PMID:1425342[1]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0141068
PMID:11283698[6]

TAS: Traceable Author Statement

P

From FB

GO:0008063

Toll signaling pathway

FB:FBrf0141086
PMID:11135568[7]

NAS: Non-traceable Author Statement

P

From FB

GO:0008233

peptidase activity

FB:FBrf0133282

NAS: Non-traceable Author Statement

F

From FB

GO:0008233

peptidase activity

FB:FBrf0141281
PMID:11700289[4]

TAS: Traceable Author Statement

F

From FB

GO:0008236

serine-type peptidase activity

FB:FBrf0110978
PMID:10449356[5]

NAS: Non-traceable Author Statement

F

From FB

GO:0008236

serine-type peptidase activity

FB:FBrf0123583

NAS: Non-traceable Author Statement

F

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0055883
PMID:1425342[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0123583

NAS: Non-traceable Author Statement

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0127230
PMID:10793472[8]

TAS: Traceable Author Statement

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0141281
PMID:11700289[4]

TAS: Traceable Author Statement

P

From FB

GO:0031638

zymogen activation

FB:FBrf0190205
PMID:16399077[9]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Chasan R et al. (1992) Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo. Development 115: 607-16 PubMed GONUTS page
  2. Coates D et al. (2000) Exploring the Caenorhabditis elegans and Drosophila melanogaster genomes to understand neuropeptide and peptidase function. Biochem Soc Trans 28: 464-9 PubMed GONUTS page
  3. 3.0 3.1 Ross J et al. (2003) Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 304: 117-31 PubMed GONUTS page
  4. 4.0 4.1 4.2 Lall S & Patel NH (2001) Conservation and divergence in molecular mechanisms of axis formation. Annu Rev Genet 35: 407-37 PubMed GONUTS page
  5. 5.0 5.1 van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
  6. Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
  7. Beutler B & Poltorak A (2001) Toll we meet again.... Nat Immunol 2: 9-10 PubMed GONUTS page
  8. Meister M et al. (2000) The antimicrobial host defense of Drosophila. Curr Top Microbiol Immunol 248: 17-36 PubMed GONUTS page
  9. Jang IH et al. (2006) A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. Dev Cell 10: 45-55 PubMed GONUTS page
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