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FB:eIF4G

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) eIF4G ( synonyms: CG10811, EIF4G, Eif4G, Eukaryotic initiation factor 4G, Eukaryotic-initiation-factor-4G, deIF4G, eIF-4G, eIF4g, eukaryotic initiation factor 4G, p200, translation initiation factor, translation initiation factor eIF4G )
Protein Name(s) eukaryotic translation initiation factor 4G,
External Links
FB FBgn0023213

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000022

mitotic spindle elongation

FB:FBrf0200397
PMID:17412918[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000082

G1/S transition of mitotic cell cycle

FB:FBrf0202425
PMID:17611222[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000340

RNA 7-methylguanosine cap binding

FB:FBrf0202425
PMID:17611222[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003723

RNA binding

FB:FBrf0074884
PMID:8027064[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003743

translation initiation factor activity

FB:FBrf0102330
PMID:9578457[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:3296
SGD:S000003394

F

From FB

GO:0003743

translation initiation factor activity

FB:FBrf0129923
PMID:10908586[5]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005829

cytosol

FB:FBrf0129923
PMID:10908586[5]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006412

translation

FB:FBrf0074884
PMID:8027064[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0006413

translational initiation

FB:FBrf0102330
PMID:9578457[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:3296
SGD:S000003394

P

From FB

GO:0006413

translational initiation

FB:FBrf0129923
PMID:10908586[5]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007052

mitotic spindle organization

FB:FBrf0200397
PMID:17412918[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0207149
PMID:18463163[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0102330
PMID:9578457[4]

IPI: Inferred from Physical Interaction

FB:FBgn0015218

F

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0184136
PMID:15804566[8]

IPI: Inferred from Physical Interaction

FB:FBgn0015218

F

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0184136
PMID:15804566[8]

IPI: Inferred from Physical Interaction

FB:FBgn0035709

F

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0184136
PMID:15804566[8]

IPI: Inferred from Physical Interaction

FB:FBgn0035823

F

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0184136
PMID:15804566[8]

IPI: Inferred from Physical Interaction

FB:FBgn0035860

F

From FB

GO:0008190

eukaryotic initiation factor 4E binding

FB:FBrf0184136
PMID:15804566[8]

IPI: Inferred from Physical Interaction

FB:FBgn0040368

F

From FB

GO:0016070

RNA metabolic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR003890
InterPro:IPR016021

P

From FB

GO:0016281

eukaryotic translation initiation factor 4F complex

FB:FBrf0074884
PMID:8027064[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0016281

eukaryotic translation initiation factor 4F complex

FB:FBrf0129923
PMID:10908586[5]

ISS: Inferred from Sequence or Structural Similarity

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  2. 2.0 2.1 Franklin-Dumont TM et al. (2007) A novel eIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes. Development 134: 2851-61 PubMed GONUTS page
  3. 3.0 3.1 3.2 Zapata JM et al. (1994) Purification and characterization of eukaryotic polypeptide chain initiation factor 4F from Drosophila melanogaster embryos. J Biol Chem 269: 18047-52 PubMed GONUTS page
  4. 4.0 4.1 4.2 Hernández G et al. (1998) Isolation and characterization of the cDNA and the gene for eukaryotic translation initiation factor 4G from Drosophila melanogaster. Eur J Biochem 253: 27-35 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  6. Ducat D et al. (2008) Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 19: 3097-110 PubMed GONUTS page
  7. Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 8.4 Hernández G et al. (2005) Functional analysis of seven genes encoding eight translation initiation factor 4E (eIF4E) isoforms in Drosophila. Mech Dev 122: 529-43 PubMed GONUTS page
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