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FB:eIF4AIII

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) eIF4AIII ( synonyms: 7483, CG7483, DmRH28, EIF4AIII, anon-WO0118547.364, eIF4A, eIF4A-III, eukaryotic translation initiation factor 4AIII, l(3)84Fi, lethal(3)84Fi )
Protein Name(s) eIF4AIII,
External Links
FB FBgn0037573

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000398

nuclear mRNA splicing, via spliceosome

FB:FBrf0207172
PMID:18981222[1]

IC: Inferred by Curator

GO:0071011
GO:0071013

P

From FB

GO:0003743

translation initiation factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P41380

F

From FB

GO:0003743

translation initiation factor activity

FB:FBrf0129923
PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004004

ATP-dependent RNA helicase activity

FB:FBrf0129923
PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

SGD:S0002428

F

From FB

GO:0005515

protein binding

FB:FBrf0174990
PMID:14973490[3]

IPI: Inferred from Physical Interaction

FB:FBgn0045862

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000629
InterPro:IPR001650
InterPro:IPR011545

F

From FB

GO:0005634

nucleus

FB:FBrf0174990
PMID:14973490[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006413

translational initiation

FB:FBrf0129923
PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006974

response to DNA damage stimulus

FB:FBrf0208272
PMID:19543366[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008380

RNA splicing

FB:FBrf0212064
PMID:20946983[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016281

eukaryotic translation initiation factor 4F complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P41380

C

From FB

GO:0016281

eukaryotic translation initiation factor 4F complex

FB:FBrf0129923
PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0045451

pole plasm oskar mRNA localization

FB:FBrf0174990
PMID:14973490[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0045862

P

From FB

GO:0045495

pole plasm

FB:FBrf0174990
PMID:14973490[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0071011

precatalytic spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0071013

catalytic step 2 spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Herold N et al. (2009) Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol 29: 281-301 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Palacios IM et al. (2004) An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature 427: 753-7 PubMed GONUTS page
  4. Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
  5. Ashton-Beaucage D et al. (2010) The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Cell 143: 251-62 PubMed GONUTS page
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