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FB:ds
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | ds ( synonyms: CG17941, CT39575, Dachsous, Ds, EP-822, cad2, cadherin-2, dachs, l(2)05142 ) | |
| Protein Name(s) | dachsous, | |
| External Links | ||
| FB | FBgn0000497 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000904 |
cell morphogenesis involved in differentiation |
FB:FBrf0081626 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0156094 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0179329 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0194266 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0211889 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001075 |
P |
From FB |
||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0211889 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001737 |
establishment of imaginal disc-derived wing hair orientation |
FB:FBrf0148937 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001737 |
establishment of imaginal disc-derived wing hair orientation |
FB:FBrf0194700 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001737 |
establishment of imaginal disc-derived wing hair orientation |
FB:FBrf0211754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001737 |
establishment of imaginal disc-derived wing hair orientation |
FB:FBrf0213159 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004871 |
signal transducer activity |
FB:FBrf0141064 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004872 |
receptor activity |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005509 |
calcium ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0081626 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0132105 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0156940 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0007156 |
homophilic cell adhesion |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007156 |
homophilic cell adhesion |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007164 |
establishment of tissue polarity |
FB:FBrf0155643 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0187296 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0194700 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007480 |
imaginal disc-derived leg morphogenesis |
FB:FBrf0187296 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008283 |
cell proliferation |
FB:FBrf0081626 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0128473 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016318 |
ommatidial rotation |
FB:FBrf0148937 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0194700 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016339 |
calcium-dependent cell-cell adhesion |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0016339 |
calcium-dependent cell-cell adhesion |
FB:FBrf0132105 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0016339 |
calcium-dependent cell-cell adhesion |
FB:FBrf0156940 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0018149 |
peptide cross-linking |
FB:FBrf0081626 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001075 |
P |
From FB |
||
| GO:0030010 |
establishment of cell polarity |
FB:FBrf0187296 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035159 |
regulation of tube length, open tracheal system |
FB:FBrf0209469 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035222 |
wing disc pattern formation |
FB:FBrf0179415 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042067 |
establishment of ommatidial planar polarity |
FB:FBrf0146910 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042067 |
establishment of ommatidial planar polarity |
FB:FBrf0156198 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045198 |
establishment of epithelial cell apical/basal polarity |
FB:FBrf0155499 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045317 |
equator specification |
FB:FBrf0151238 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048592 |
eye morphogenesis |
FB:FBrf0187296 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050839 |
cell adhesion molecule binding |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0050839 |
cell adhesion molecule binding |
FB:FBrf0179329 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0090176 |
microtubule cytoskeleton organization involved in establishment of planar polarity |
FB:FBrf0211754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Clark HF et al. (1995) Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila. Genes Dev 9: 1530-42 PubMed GONUTS page
- ↑ Mlodzik M (2002) Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet 18: 564-71 PubMed GONUTS page
- ↑ 3.0 3.1 Matakatsu H & Blair SS (2004) Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131: 3785-94 PubMed GONUTS page
- ↑ Casal J et al. (2006) Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development 133: 4561-72 PubMed GONUTS page
- ↑ 5.0 5.1 Repiso A et al. (2010) Planar cell polarity: the orientation of larval denticles in Drosophila appears to depend on gradients of Dachsous and Fat. Development 137: 3411-5 PubMed GONUTS page
- ↑ 6.0 6.1 Strutt H & Strutt D (2002) Planar polarity: photoreceptors on a high fat diet. Curr Biol 12: R384-5 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Matakatsu H & Blair SS (2006) Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. Development 133: 2315-24 PubMed GONUTS page
- ↑ 8.0 8.1 Harumoto T et al. (2010) Atypical cadherins Dachsous and Fat control dynamics of noncentrosomal microtubules in planar cell polarity. Dev Cell 19: 389-401 PubMed GONUTS page
- ↑ Hogan J et al. (2011) Two frizzled planar cell polarity signals in the Drosophila wing are differentially organized by the Fat/Dachsous pathway. PLoS Genet 7: e1001305 PubMed GONUTS page
- ↑ McNeill H (2000) Sticking together and sorting things out: adhesion as a force in development. Nat Rev Genet 1: 100-8 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 11.4 11.5 11.6 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
- ↑ Wedlich D (2002) The polarising role of cell adhesion molecules in early development. Curr Opin Cell Biol 14: 563-8 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 13.3 Baena-López LA et al. (2005) The orientation of cell divisions determines the shape of Drosophila organs. Curr Biol 15: 1640-4 PubMed GONUTS page
- ↑ Garoia F et al. (2000) Cell behaviour of Drosophila fat cadherin mutations in wing development. Mech Dev 94: 95-109 PubMed GONUTS page
- ↑ Chung S et al. (2009) Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length. PLoS Genet 5: e1000746 PubMed GONUTS page
- ↑ Rodríguez I (2004) The dachsous gene, a member of the cadherin family, is required for Wg-dependent pattern formation in the Drosophila wing disc. Development 131: 3195-206 PubMed GONUTS page
- ↑ Yang CH et al. (2002) Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108: 675-88 PubMed GONUTS page
- ↑ Tree DR et al. (2002) A three-tiered mechanism for regulation of planar cell polarity. Semin Cell Dev Biol 13: 217-24 PubMed GONUTS page
- ↑ Ma D et al. (2003) Fidelity in planar cell polarity signalling. Nature 421: 543-7 PubMed GONUTS page
- ↑ Rawls AS et al. (2002) The cadherins fat and dachsous regulate dorsal/ventral signaling in the Drosophila eye. Curr Biol 12: 1021-6 PubMed GONUTS page
