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FB:drpr
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | drpr ( synonyms: BcDNA:GH03529, CG18172, CG2086, CT41022, CT6730, Draper, Drpr ) | |
| Protein Name(s) | draper, | |
| External Links | ||
| FB | FBgn0027594 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
FB:FBrf0192438 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0006909 |
phagocytosis |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006909 |
phagocytosis |
FB:FBrf0179835 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0008345 |
larval locomotory behavior |
FB:FBrf0160527 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016322 |
neuron remodeling |
FB:FBrf0192438 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031224 |
intrinsic to membrane |
FB:FBrf0179835 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0035071 |
salivary gland cell autophagic cell death |
FB:FBrf0211145 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0201270 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043277 |
apoptotic cell clearance |
FB:FBrf0204720 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043277 |
apoptotic cell clearance |
FB:FBrf0205492 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043277 |
apoptotic cell clearance |
FB:FBrf0207750 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0202749 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000242 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Awasaki T et al. (2006) Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis. Neuron 50: 855-67 PubMed GONUTS page
- ↑ Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ 3.0 3.1 Manaka J et al. (2004) Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages. J Biol Chem 279: 48466-76 PubMed GONUTS page
- ↑ Freeman MR et al. (2003) Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function. Neuron 38: 567-80 PubMed GONUTS page
- ↑ McPhee CK et al. (2010) Activation of autophagy during cell death requires the engulfment receptor Draper. Nature 465: 1093-6 PubMed GONUTS page
- ↑ Li W & Baker NE (2007) Engulfment is required for cell competition. Cell 129: 1215-25 PubMed GONUTS page
- ↑ Kurant E et al. (2008) Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons. Cell 133: 498-509 PubMed GONUTS page
- ↑ Ziegenfuss JS et al. (2008) Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature 453: 935-9 PubMed GONUTS page
- ↑ Doherty J et al. (2009) Ensheathing glia function as phagocytes in the adult Drosophila brain. J Neurosci 29: 4768-81 PubMed GONUTS page
- ↑ Bejarano F et al. (2008) A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Genetics 178: 307-23 PubMed GONUTS page
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