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FB:dos

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) dos ( synonyms: 141511_at, CG1044, DOS, Daughter of Sevenless, Dos, E(csw)3A, E(csw(CS))3A, Enhancer of corkscrew-CS, Gab-1, Su(sev)3A, Su(sev(S11))3A, Suppressor of sevenless-S11 )
Protein Name(s) daughter of sevenless,
External Links
FB FBgn0016794

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005070

SH3/SH2 adaptor activity

FB:FBrf0088815
PMID:8681385[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005515

protein binding

FB:FBrf0151405
PMID:12128212[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q08012

F

From FB

GO:0005543

phospholipid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From FB

GO:0005737

cytoplasm

FB:FBrf0126713
PMID:10640704[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0088815
PMID:8681385[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0008293

torso signaling pathway

FB:FBrf0111327
PMID:10494038[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0008595

anterior/posterior axis specification, embryo

FB:FBrf0111327
PMID:10494038[4]

TAS: Traceable Author Statement

P

From FB

GO:0019730

antimicrobial humoral response

FB:FBrf0190362
PMID:16163390[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042169

SH2 domain binding

FB:FBrf0102661
PMID:9582352[6]

IPI: Inferred from Physical Interaction

FB:FBgn0000382

F

From FB

GO:0045500

sevenless signaling pathway

FB:FBrf0129916
PMID:10929403[7]

TAS: Traceable Author Statement

P

From FB

GO:0046578

regulation of Ras protein signal transduction

FB:FBrf0151405
PMID:12128212[2]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Raabe T et al. (1996) DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila. Cell 85: 911-20 PubMed GONUTS page
  2. 2.0 2.1 Feller SM et al. (2002) SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases. Mech Dev 116: 129-39 PubMed GONUTS page
  3. Bausenwein BS et al. (2000) In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling. Mech Dev 90: 205-15 PubMed GONUTS page
  4. 4.0 4.1 Baek KH & Lee KY (1999) Signal transduction pathway for anterior-posterior development in Drosophila. J Biomed Sci 6: 314-9 PubMed GONUTS page
  5. Kleino A et al. (2005) Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. EMBO J 24: 3423-34 PubMed GONUTS page
  6. Allard JD et al. (1998) Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew. J Biol Chem 273: 13129-35 PubMed GONUTS page
  7. Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
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