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FB:dome

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) dome ( synonyms: 142932_at, CG14226, CT33841, DOME, Dome, Dome receptor, Domeless, anon-18DEb, l(1)G0217, l(1)G0218, l(1)G0264, l(1)G0282, l(1)G0321, l(1)G0367, l(1)G0405, l(1)G0441, l(1)G0468, master of marelle, mom, verstopft, vsp )
Protein Name(s) domeless,
External Links
FB FBgn0043903

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

FB:FBrf0179489
PMID:15170700[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0002009

morphogenesis of an epithelium

FB:FBrf0146164

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004725

protein tyrosine phosphatase activity

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141438
PMID:11696329[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0004956

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

HGNC:2170

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

HGNC:6597

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:96788

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:99605

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0151864
PMID:12194841[4]

TAS: Traceable Author Statement

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0178966
PMID:15199955[5]

TAS: Traceable Author Statement

F

From FB

GO:0005886

plasma membrane

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

HGNC:2170

C

From FB

GO:0005886

plasma membrane

FB:FBrf0141438
PMID:11696329[3]

ISS: Inferred from Sequence or Structural Similarity

HGNC:6597

C

From FB

GO:0005886

plasma membrane

FB:FBrf0146164

NAS: Non-traceable Author Statement

C

From FB

GO:0006470

protein dephosphorylation

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0006955

immune response

FB:FBrf0178966
PMID:15199955[5]

TAS: Traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0133485

NAS: Non-traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0141438
PMID:11696329[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0004956

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0141438
PMID:11696329[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0016917

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0141913

NAS: Non-traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0144881
PMID:11825879[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0004864

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0144881
PMID:11825879[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0004956

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0146668

NAS: Non-traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0151864
PMID:12194841[4]

TAS: Traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0152778

NAS: Non-traceable Author Statement

P

From FB

GO:0007259

JAK-STAT cascade

FB:FBrf0178966
PMID:15199955[5]

TAS: Traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0151938
PMID:12403714[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0187473
PMID:15944190[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007350

blastoderm segmentation

FB:FBrf0140132

NAS: Non-traceable Author Statement

P

From FB

GO:0007350

blastoderm segmentation

FB:FBrf0141438
PMID:11696329[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0140132

NAS: Non-traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0141438
PMID:11696329[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0144881
PMID:11825879[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0194228
PMID:17113384[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007425

epithelial cell fate determination, open tracheal system

FB:FBrf0167264
PMID:14570584[10]

TAS: Traceable Author Statement

P

From FB

GO:0007442

hindgut morphogenesis

FB:FBrf0151948
PMID:12441298[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007616

long-term memory

FB:FBrf0213703
PMID:21518857[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008284

positive regulation of cell proliferation

FB:FBrf0212840
PMID:21176204[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016324

apical plasma membrane

FB:FBrf0151864
PMID:12194841[4]

TAS: Traceable Author Statement

C

From FB

GO:0016327

apicolateral plasma membrane

FB:FBrf0151938
PMID:12403714[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0019955

cytokine binding

FB:FBrf0152778

NAS: Non-traceable Author Statement

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0211466
PMID:20689801[14]

IPI: Inferred from Physical Interaction

FB:FBgn0031055

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Tsai YC & Sun YH (2004) Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. Genesis 39: 141-53 PubMed GONUTS page
  2. 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 Brown S et al. (2001) Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless. Curr Biol 11: 1700-5 PubMed GONUTS page
  4. 4.0 4.1 4.2 Hombría JC & Brown S (2002) The fertile field of Drosophila Jak/STAT signalling. Curr Biol 12: R569-75 PubMed GONUTS page
  5. 5.0 5.1 5.2 Agaisse H & Perrimon N (2004) The roles of JAK/STAT signaling in Drosophila immune responses. Immunol Rev 198: 72-82 PubMed GONUTS page
  6. 6.0 6.1 6.2 Chen HW et al. (2002) mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family. Genes Dev 16: 388-98 PubMed GONUTS page
  7. 7.0 7.1 Ghiglione C et al. (2002) The Drosophila cytokine receptor Domeless controls border cell migration and epithelial polarization during oogenesis. Development 129: 5437-47 PubMed GONUTS page
  8. Medioni C & Noselli S (2005) Dynamics of the basement membrane in invasive epithelial clusters in Drosophila. Development 132: 3069-77 PubMed GONUTS page
  9. Lovegrove B et al. (2006) Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila. Curr Biol 16: 2206-16 PubMed GONUTS page
  10. Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  11. Johansen KA et al. (2003) Localized JAK/STAT signaling is required for oriented cell rearrangement in a tubular epithelium. Development 130: 135-45 PubMed GONUTS page
  12. Copf T et al. (2011) Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila. Proc Natl Acad Sci U S A 108: 8059-64 PubMed GONUTS page
  13. Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
  14. Makki R et al. (2010) A short receptor downregulates JAK/STAT signalling to control the Drosophila cellular immune response. PLoS Biol 8: e1000441 PubMed GONUTS page
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