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FB:dm
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | dm ( synonyms: CG10798, D-Myc, DMYc, Dm, Dmyc, EG:BACN5I9.1, MYC, Myc, anon-WO03040301.171, bHLHe57, c-MYC, c-Myc, c-myc, d-myc, dMYC, dMyc, dMyc1, dm/dMyc, dm/myc, dmyc, dmyc1, l(1)G0139, l(1)G0354, l(1)G0359, lethal (1) G0354, lethal (1) G0359, myc ) | |
| Protein Name(s) | diminutive, | |
| External Links | ||
| FB | FBgn0262656 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001558 |
regulation of cell growth |
FB:FBrf0188250 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0090563 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0090563 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0092678 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:L00039 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0193047 |
IPI: Inferred from Physical Interaction |
FB:FBgn0031759 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0200831 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001139 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:L00039 |
C |
From FB |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0090563 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0188102 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008283 |
cell proliferation |
FB:FBrf0092678 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009792 |
embryo development ending in birth or egg hatching |
FB:FBrf0092678 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0009880 |
embryonic pattern specification |
FB:FBrf0200831 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0009987 |
cellular process |
FB:FBrf0175143 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0200831 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0125443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0136845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0141377 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0162295 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0174444 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0174445 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035212 |
cell competition in a multicellular organism |
FB:FBrf0211944 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0141377 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0167538 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0174581 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042981 |
regulation of apoptotic process |
FB:FBrf0202778 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043234 |
protein complex |
FB:FBrf0200831 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001139 |
C |
From FB |
||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0200831 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004647 |
P |
From FB |
||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0200831 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045927 |
positive regulation of growth |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045927 |
positive regulation of growth |
FB:FBrf0212501 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0174444 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0044470 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0141377 |
TAS: Traceable Author Statement |
P |
From FB |
|||
|
colocalizes_with |
GO:0035363 |
histone locus body |
FB:FBrf0215022 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Bellosta P et al. (2005) Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development. Proc Natl Acad Sci U S A 102: 11799-804 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gallant P et al. (1996) Myc and Max homologs in Drosophila. Science 274: 1523-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Schreiber-Agus N et al. (1997) Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype. Proc Natl Acad Sci U S A 94: 1235-40 PubMed GONUTS page
- ↑ Secombe J et al. (2007) The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev 21: 537-51 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Orian A et al. (2007) A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development. Proc Natl Acad Sci U S A 104: 15771-6 PubMed GONUTS page
- ↑ Hulf T et al. (2005) Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes. Mol Cell Biol 25: 3401-10 PubMed GONUTS page
- ↑ 7.0 7.1 Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
- ↑ Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
- ↑ Weinkove D & Leevers SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr Opin Genet Dev 10: 75-80 PubMed GONUTS page
- ↑ Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page
- ↑ Bergmann A & Lane ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem Sci 28: 461-3 PubMed GONUTS page
- ↑ 13.0 13.1 de la Cova C et al. (2004) Drosophila myc regulates organ size by inducing cell competition. Cell 117: 107-16 PubMed GONUTS page
- ↑ Moreno E & Basler K (2004) dMyc transforms cells into super-competitors. Cell 117: 117-29 PubMed GONUTS page
- ↑ Ziosi M et al. (2010) dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells. PLoS Genet 6: PubMed GONUTS page
- ↑ Maines JZ et al. (2004) Drosophila dMyc is required for ovary cell growth and endoreplication. Development 131: 775-86 PubMed GONUTS page
- ↑ Pierce SB et al. (2004) dMyc is required for larval growth and endoreplication in Drosophila. Development 131: 2317-27 PubMed GONUTS page
- ↑ Montero L et al. (2008) Induction of apoptosis by Drosophila Myc. Genesis 46: 104-11 PubMed GONUTS page
- ↑ Furrer M et al. (2010) Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth. J Biol Chem 285: 39623-36 PubMed GONUTS page
- ↑ Perrimon N et al. (1986) X-linked female-sterile loci in Drosophila melanogaster. Genetics 113: 695-712 PubMed GONUTS page
- ↑ Daneshvar K et al. (2011) Myc localizes to histone locus bodies during replication in Drosophila. PLoS One 6: e23928 PubMed GONUTS page
