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FB:dia
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | dia ( synonyms: 38E.16, CG1768, DIA, Dia, Diaphanous, Dias, l(2)k07135, ms(2)04138 ) | |
| Protein Name(s) | diaphanous, | |
| External Links | ||
| FB | FBgn0011202 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000910 |
cytokinesis |
FB:FBrf0124086 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0149002 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0151773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0162189 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0180064 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0180476 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0191432 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000915 |
cytokinesis, actomyosin contractile ring assembly |
FB:FBrf0141282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000915 |
cytokinesis, actomyosin contractile ring assembly |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003383 |
apical constriction |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0207596 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000308 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0207596 |
IPI: Inferred from Physical Interaction |
FB:FBgn0026598 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0207596 |
IPI: Inferred from Physical Interaction |
FB:FBgn0027066 |
F |
From FB |
||
| GO:0005826 |
actomyosin contractile ring |
FB:FBrf0124086 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005912 |
adherens junction |
FB:FBrf0204461 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0204461 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0126984 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0183918 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007110 |
cytokinesis after meiosis I |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007111 |
cytokinesis after meiosis II |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007279 |
pole cell formation |
FB:FBrf0126984 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007283 |
spermatogenesis |
FB:FBrf0064394 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007349 |
cellularization |
FB:FBrf0126984 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007349 |
cellularization |
FB:FBrf0141282 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007349 |
cellularization |
FB:FBrf0151773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007349 |
cellularization |
FB:FBrf0183918 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0190308 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007605 |
sensory perception of sound |
FB:FBrf0206525 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007605 |
sensory perception of sound |
FB:FBrf0211399 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0126984 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0134594 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0151773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009306 |
protein secretion |
FB:FBrf0208270 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016476 |
regulation of embryonic cell shape |
FB:FBrf0204461 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016476 |
regulation of embryonic cell shape |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017048 |
Rho GTPase binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030029 |
actin filament-based process |
FB:FBrf0149002 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030029 |
actin filament-based process |
FB:FBrf0151773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030589 |
pseudocleavage involved in syncytial blastoderm formation |
FB:FBrf0207596 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0032154 |
cleavage furrow |
FB:FBrf0204461 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0032507 |
maintenance of protein location in cell |
FB:FBrf0191432 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043234 |
protein complex |
FB:FBrf0207596 |
IPI: Inferred from Physical Interaction |
FB:FBgn0026598 |
C |
From FB |
||
| GO:0045177 |
apical part of cell |
FB:FBrf0202245 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045177 |
apical part of cell |
FB:FBrf0208270 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045448 |
mitotic cell cycle, embryonic |
FB:FBrf0126984 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051225 |
spindle assembly |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0005884 |
actin filament |
FB:FBrf0207596 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Van Aelst L & Symons M (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 16: 1032-54 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Mazumdar A & Mazumdar M (2002) How one becomes many: blastoderm cellularization in Drosophila melanogaster. Bioessays 24: 1012-22 PubMed GONUTS page
- ↑ Rogers SL et al. (2003) Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol 162: 1079-88 PubMed GONUTS page
- ↑ 4.0 4.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
- ↑ Eggert US et al. (2004) Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol 2: e379 PubMed GONUTS page
- ↑ 7.0 7.1 Dean SO et al. (2005) Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci U S A 102: 13473-8 PubMed GONUTS page
- ↑ 8.0 8.1 Tepass U et al. (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35: 747-84 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Giansanti MG et al. (2004) Genetic dissection of meiotic cytokinesis in Drosophila males. Mol Biol Cell 15: 2509-22 PubMed GONUTS page
- ↑ 10.0 10.1 Bertet C et al. (2009) Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells. Development 136: 4199-212 PubMed GONUTS page
- ↑ Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 12.3 12.4 12.5 Webb RL et al. (2009) A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila. Development 136: 1283-93 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 13.3 Homem CC & Peifer M (2008) Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis. Development 135: 1005-18 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 14.3 14.4 Afshar K et al. (2000) Functional analysis of the Drosophila diaphanous FH protein in early embryonic development. Development 127: 1887-97 PubMed GONUTS page
- ↑ 15.0 15.1 Grosshans J et al. (2005) RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation. Development 132: 1009-20 PubMed GONUTS page
- ↑ Castrillon DH et al. (1993) Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135: 489-505 PubMed GONUTS page
- ↑ Matusek T et al. (2006) The Drosophila formin DAAM regulates the tracheal cuticle pattern through organizing the actin cytoskeleton. Development 133: 957-66 PubMed GONUTS page
- ↑ Cosetti M et al. (2008) Unique transgenic animal model for hereditary hearing loss. Ann Otol Rhinol Laryngol 117: 827-33 PubMed GONUTS page
- ↑ Schoen CJ et al. (2010) Increased activity of Diaphanous homolog 3 (DIAPH3)/diaphanous causes hearing defects in humans with auditory neuropathy and in Drosophila. Proc Natl Acad Sci U S A 107: 13396-401 PubMed GONUTS page
- ↑ Gonzalez C & Bornens M (2000) Light, flies and cell division. Workshop: regulation of cell division in Drosophila. EMBO Rep 1: 390-3 PubMed GONUTS page
- ↑ 21.0 21.1 Massarwa R et al. (2009) Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous. Dev Cell 16: 877-88 PubMed GONUTS page
- ↑ Corrigall D et al. (2007) Hedgehog signaling is a principal inducer of Myosin-II-driven cell ingression in Drosophila epithelia. Dev Cell 13: 730-42 PubMed GONUTS page
