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FB:dap

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) dap ( synonyms: CDI4, CDKN2B, CG1772, CIB1, Cdi4, Cyclin-dependent kinase interactor 4, Dacap0, Dacapo, Dacapo/p21, Dap, Decapo, E(Sev-CycE)2B, P15, cdi4, chakra, dacapo/cyclin-dependent kinase interactor 4, decapo, l(2)04454, p21, p21/Dacapo, p21/dacapo, p21(dacapo), p27, p27(Dap) )
Protein Name(s) dacapo,
External Links
FB FBgn0010316

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000079

regulation of cyclin-dependent protein kinase activity

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0000082

G1/S transition of mitotic cell cycle

FB:FBrf0086753

NAS: Non-traceable Author Statement

P

From FB

GO:0004861

cyclin-dependent protein kinase inhibitor activity

FB:FBrf0086753

NAS: Non-traceable Author Statement

F

From FB

GO:0004861

cyclin-dependent protein kinase inhibitor activity

FB:FBrf0091107
PMID:8980229[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0004861

cyclin-dependent protein kinase inhibitor activity

FB:FBrf0091210
PMID:8980230[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0004861

cyclin-dependent protein kinase inhibitor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q64315

F

From FB

GO:0004861

cyclin-dependent protein kinase inhibitor activity

FB:FBrf0114466

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0091107
PMID:8980229[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007050

cell cycle arrest

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR003175

P

From FB

GO:0007294

germarium-derived oocyte fate determination

FB:FBrf0155699
PMID:12588841[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007423

sensory organ development

FB:FBrf0161750

NAS: Non-traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0125237
PMID:10684581[5]

TAS: Traceable Author Statement

P

From FB

GO:0007488

histoblast morphogenesis

FB:FBrf0194691
PMID:17166923[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035308

negative regulation of protein dephosphorylation

FB:FBrf0091107
PMID:8980229[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0035308

negative regulation of protein dephosphorylation

FB:FBrf0091210
PMID:8980230[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0045035

sensory organ precursor cell division

FB:FBrf0187449
PMID:15829522[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045749

negative regulation of S phase of mitotic cell cycle

FB:FBrf0187405
PMID:15809036[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045786

negative regulation of cell cycle

FB:FBrf0125237
PMID:10684581[5]

TAS: Traceable Author Statement

P

From FB

GO:0045859

regulation of protein kinase activity

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0048477

oogenesis

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0051318

G1 phase

FB:FBrf0193620
PMID:17055987[9]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lane ME et al. (1996) Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87: 1225-35 PubMed GONUTS page
  3. 3.0 3.1 de Nooij JC et al. (1996) A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell 87: 1237-47 PubMed GONUTS page
  4. Hong A et al. (2003) The p27cip/kip ortholog dacapo maintains the Drosophila oocyte in prophase of meiosis I. Development 130: 1235-42 PubMed GONUTS page
  5. 5.0 5.1 Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
  6. Ninov N et al. (2007) Extrinsic and intrinsic mechanisms directing epithelial cell sheet replacement during Drosophila metamorphosis. Development 134: 367-79 PubMed GONUTS page
  7. Audibert A et al. (2005) Cell cycle diversity involves differential regulation of Cyclin E activity in the Drosophila bristle cell lineage. Development 132: 2287-97 PubMed GONUTS page
  8. Firth LC & Baker NE (2005) Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye. Dev Cell 8: 541-51 PubMed GONUTS page
  9. Parker J (2006) Control of compartment size by an EGF ligand from neighboring cells. Curr Biol 16: 2058-65 PubMed GONUTS page
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