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FB:cyc
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | cyc ( synonyms: BMAL1, Bmal1, CG8727, CYC, CYCLE, Cyc, Cycle, MOP3, Mop3, bHLHe7, bMAL1, bmal1, brain and muscle ARNT-like 1, dBMAL, dBMAL1, dBma1, dBmal, dCYC, dbmal, dbmal1 ) | |
| Protein Name(s) | cycle, | |
| External Links | ||
| FB | FBgn0023094 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0182901 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0190570 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0123307 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0004871 |
signal transducer activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123307 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0149124 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005667 |
transcription factor complex |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007622 |
rhythmic behavior |
FB:FBrf0155881 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0123307 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0141665 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0149124 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0156173 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0159046 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0179906 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007623 |
circadian rhythm |
FB:FBrf0182901 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008062 |
eclosion rhythm |
FB:FBrf0141665 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008062 |
eclosion rhythm |
FB:FBrf0155881 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0032922 |
circadian regulation of gene expression |
FB:FBrf0202091 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042594 |
response to starvation |
FB:FBrf0206097 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045187 |
regulation of circadian sleep/wake cycle, sleep |
FB:FBrf0149122 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045187 |
regulation of circadian sleep/wake cycle, sleep |
FB:FBrf0159046 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045187 |
regulation of circadian sleep/wake cycle, sleep |
FB:FBrf0159070 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045187 |
regulation of circadian sleep/wake cycle, sleep |
FB:FBrf0195242 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0141665 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0155881 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0149124 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0156173 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0155881 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0182901 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0110163 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023076 |
F |
From FB |
||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0182901 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0208031 |
IPI: Inferred from Physical Interaction |
F |
From FB |
|||
| GO:0048148 |
behavioral response to cocaine |
FB:FBrf0141665 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0048148 |
behavioral response to cocaine |
FB:FBrf0155655 |
TAS: Traceable Author Statement |
P |
From FB |
|||
|
contributes_to |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
FB:FBrf0110163 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023076 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Hardin PE (2000) From biological clock to biological rhythms. Genome Biol 1: REVIEWS1023 PubMed GONUTS page
- ↑ Yu W et al. (2006) PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. Genes Dev 20: 723-33 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Panda S et al. (2002) Circadian rhythms from flies to human. Nature 417: 329-35 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Stanewsky R (2003) Genetic analysis of the circadian system in Drosophila melanogaster and mammals. J Neurobiol 54: 111-47 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Sokolowski MB (2001) Drosophila: genetics meets behaviour. Nat Rev Genet 2: 879-90 PubMed GONUTS page
- ↑ 6.0 6.1 Glossop NR & Hardin PE (2002) Central and peripheral circadian oscillator mechanisms in flies and mammals. J Cell Sci 115: 3369-77 PubMed GONUTS page
- ↑ 7.0 7.1 Shaw PJ & Franken P (2003) Perchance to dream: solving the mystery of sleep through genetic analysis. J Neurobiol 54: 179-202 PubMed GONUTS page
- ↑ Emery P & Reppert SM (2004) A rhythmic Ror. Neuron 43: 443-6 PubMed GONUTS page
- ↑ Hung HC et al. (2007) Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP. J Biol Chem 282: 31349-57 PubMed GONUTS page
- ↑ Xu K et al. (2008) Regulation of feeding and metabolism by neuronal and peripheral clocks in Drosophila. Cell Metab 8: 289-300 PubMed GONUTS page
- ↑ Shaw PJ et al. (2002) Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature 417: 287-91 PubMed GONUTS page
- ↑ Hendricks JC (2003) Invited review: Sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms. J Appl Physiol 94: 1660-72; discussion 1673 PubMed GONUTS page
- ↑ Yuan Q et al. (2006) A sleep-promoting role for the Drosophila serotonin receptor 1A. Curr Biol 16: 1051-62 PubMed GONUTS page
- ↑ 14.0 14.1 Lee C et al. (1999) PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription. Mol Cell Biol 19: 5316-25 PubMed GONUTS page
- ↑ Maurer C et al. (2009) Cytoplasmic interaction with CYCLE promotes the post-translational processing of the circadian CLOCK protein. FEBS Lett 583: 1561-6 PubMed GONUTS page
- ↑ Rothenfluh A & Heberlein U (2002) Drugs, flies, and videotape: the effects of ethanol and cocaine on Drosophila locomotion. Curr Opin Neurobiol 12: 639-45 PubMed GONUTS page
