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FB:cup
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | cup ( synonyms: CG11181, CUP, Cup, fs(1)cup, fs(2)cup, i239 ) | |
| Protein Name(s) | cup, | |
| External Links | ||
| FB | FBgn0000392 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000932 |
cytoplasmic mRNA processing body |
FB:FBrf0211219 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0003723 |
RNA binding |
FB:FBrf0189903 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0131417 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002962 |
F |
From FB |
||
| GO:0005641 |
nuclear envelope lumen |
FB:FBrf0093133 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0093133 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0206831 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0093133 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0006417 |
regulation of translation |
FB:FBrf0167488 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007143 |
female meiosis |
FB:FBrf0131417 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002962 |
P |
From FB |
||
| GO:0007297 |
ovarian follicle cell migration |
FB:FBrf0054123 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007317 |
regulation of pole plasm oskar mRNA localization |
FB:FBrf0167768 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007317 |
regulation of pole plasm oskar mRNA localization |
FB:FBrf0167769 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0167769 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007319 |
negative regulation of oskar mRNA translation |
FB:FBrf0189903 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0008298 |
intracellular mRNA localization |
FB:FBrf0203066 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
FB:FBrf0203066 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0167556 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015218 |
P |
From FB |
||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0203066 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045132 |
meiotic chromosome segregation |
FB:FBrf0093133 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045182 |
translation regulator activity |
FB:FBrf0167488 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0054123 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0131417 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0203066 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0051297 |
centrosome organization |
FB:FBrf0212030 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cauchi RJ et al. (2010) Drosophila SMN complex proteins Gemin2, Gemin3, and Gemin5 are components of U bodies. Exp Cell Res 316: 2354-64 PubMed GONUTS page
- ↑ 2.0 2.1 Chekulaeva M et al. (2006) Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell 124: 521-33 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Verrotti AC & Wharton RP (2000) Nanos interacts with cup in the female germline of Drosophila. Development 127: 5225-32 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Keyes LN & Spradling AC (1997) The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes. Development 124: 1419-31 PubMed GONUTS page
- ↑ Pisa V et al. (2009) The molecular chaperone Hsp90 is a component of the cap-binding complex and interacts with the translational repressor Cup during Drosophila oogenesis. Gene 432: 67-74 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ 7.0 7.1 Nakamura A et al. (2004) Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis. Dev Cell 6: 69-78 PubMed GONUTS page
- ↑ 8.0 8.1 Schüpbach T & Wieschaus E (1991) Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129: 1119-36 PubMed GONUTS page
- ↑ Lasko P (2003) Cup-ling oskar RNA localization and translational control. J Cell Biol 163: 1189-91 PubMed GONUTS page
- ↑ 10.0 10.1 Wilhelm JE et al. (2003) Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz. J Cell Biol 163: 1197-204 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 Clouse KN et al. (2008) Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila. Dev Biol 313: 713-24 PubMed GONUTS page
- ↑ Nelson MR et al. (2004) Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression. EMBO J 23: 150-9 PubMed GONUTS page
- ↑ 13.0 13.1 Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
