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FB:csw
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | csw ( synonyms: 19-106, CG3954, CSW, Corkscrew, Csw, Csw/Shp2, E(sev)1A, EG:BACN25G24.2, Enhancer of sevenless 1A, SHP-2, Shp-2, Shp2/csw, anon-WO03040301.207, anon-WO03040301.209, anon-WO03040301.219, l(1)2Db, l(1)2Dd, l(1)G0170, l(1)GA114, l(1)csw ) | |
| Protein Name(s) | corkscrew, | |
| External Links | ||
| FB | FBgn0000382 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000278 |
mitotic cell cycle |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004725 |
protein tyrosine phosphatase activity |
FB:FBrf0088202 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004725 |
protein tyrosine phosphatase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
FB:FBrf0055550 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
FB:FBrf0123917 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004728 |
receptor signaling protein tyrosine phosphatase activity |
FB:FBrf0100769 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0102661 |
IPI: Inferred from Physical Interaction |
FB:FBgn0016794 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0123917 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0088202 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0053392 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0090739 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007362 |
terminal region determination |
FB:FBrf0055550 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007418 |
ventral midline development |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0190302 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0014135 |
P |
From FB |
||
| GO:0007427 |
epithelial cell migration, open tracheal system |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007428 |
primary branching, open tracheal system |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007444 |
imaginal disc development |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007465 |
R7 cell fate commitment |
FB:FBrf0053392 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003366 |
P |
From FB |
||
| GO:0007498 |
mesoderm development |
FB:FBrf0141548 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008069 |
dorsal/ventral axis specification, ovarian follicular epithelium |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0055550 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0100769 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0102528 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0111327 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0123917 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008543 |
fibroblast growth factor receptor signaling pathway |
FB:FBrf0090739 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008595 |
anterior/posterior axis specification, embryo |
FB:FBrf0111327 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045314 |
regulation of compound eye photoreceptor development |
FB:FBrf0190302 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045500 |
sevenless signaling pathway |
FB:FBrf0129916 |
TAS: Traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chen F et al. (2007) Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol 17: 293-303 PubMed GONUTS page
- ↑ 2.0 2.1 Herbst R et al. (1996) Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. Cell 85: 899-909 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Perkins LA et al. (1992) corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell 70: 225-36 PubMed GONUTS page
- ↑ 5.0 5.1 Van Vactor D et al. (1998) Genetic analysis of protein tyrosine phosphatases. Curr Opin Genet Dev 8: 112-26 PubMed GONUTS page
- ↑ Allard JD et al. (1998) Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew. J Biol Chem 273: 13129-35 PubMed GONUTS page
- ↑ 7.0 7.1 Simon MA et al. (1991) Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67: 701-16 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Perkins LA et al. (1996) The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Dev Biol 180: 63-81 PubMed GONUTS page
- ↑ 9.0 9.1 Jarvis LA et al. (2006) Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases. Development 133: 1133-42 PubMed GONUTS page
- ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ Johnson Hamlet MR & Perkins LA (2001) Analysis of corkscrew signaling in the Drosophila epidermal growth factor receptor pathway during myogenesis. Genetics 159: 1073-87 PubMed GONUTS page
- ↑ Bier E (1998) Localized activation of RTK/MAPK pathways during Drosophila development. Bioessays 20: 189-94 PubMed GONUTS page
- ↑ 13.0 13.1 Baek KH & Lee KY (1999) Signal transduction pathway for anterior-posterior development in Drosophila. J Biomed Sci 6: 314-9 PubMed GONUTS page
- ↑ Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
