GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:crn
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | crn ( synonyms: 62D9.a, CG18842, CG3193, Crn, EG:30B8.1, N10, N5, RC63, l(1)2, l(1)2Fa, l(1)CRN, l(1)N7, l(1)crn, l30, yok, yolky ) | |
| Protein Name(s) | crooked neck, | |
| External Links | ||
| FB | FBgn0000377 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000381 |
regulation of alternative nuclear mRNA splicing, via spliceosome |
FB:FBrf0180650 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000381 |
regulation of alternative nuclear mRNA splicing, via spliceosome |
FB:FBrf0192282 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000381 |
regulation of alternative nuclear mRNA splicing, via spliceosome |
FB:FBrf0207843 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000398 |
nuclear mRNA splicing, via spliceosome |
FB:FBrf0129982 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_NP:013218 |
P |
From FB |
||
| GO:0000398 |
nuclear mRNA splicing, via spliceosome |
FB:FBrf0207172 |
IC: Inferred by Curator |
GO:0071011 GO:0071013 |
P |
From FB |
||
| GO:0005488 |
binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123661 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0180650 |
IC: Inferred by Curator |
GO:0000381 |
C |
From FB |
||
| GO:0005681 |
spliceosomal complex |
FB:FBrf0129982 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_NP:013218 |
C |
From FB |
||
| GO:0005813 |
centrosome |
FB:FBrf0212030 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007405 |
neuroblast proliferation |
FB:FBrf0123661 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007417 |
central nervous system development |
FB:FBrf0123661 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0123661 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007438 |
oenocyte development |
FB:FBrf0194634 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007443 |
Malpighian tubule morphogenesis |
FB:FBrf0111391 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008347 |
glial cell migration |
FB:FBrf0194634 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008366 |
axon ensheathment |
FB:FBrf0194634 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016607 |
nuclear speck |
FB:FBrf0151213 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048663 |
neuron fate commitment |
FB:FBrf0123661 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0051298 |
centrosome duplication |
FB:FBrf0212030 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071011 |
precatalytic spliceosome |
FB:FBrf0207172 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0071013 |
catalytic step 2 spliceosome |
FB:FBrf0207172 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0072686 |
mitotic spindle |
FB:FBrf0212030 |
IDA: Inferred from Direct Assay |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Park JW et al. (2004) Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A 101: 15974-9 PubMed GONUTS page
- ↑ Volohonsky G et al. (2007) Muscle-dependent maturation of tendon cells is induced by post-transcriptional regulation of stripeA. Development 134: 347-56 PubMed GONUTS page
- ↑ Katzenberger RJ et al. (2009) Control of alternative splicing by signal-dependent degradation of splicing-regulatory proteins. J Biol Chem 284: 10737-46 PubMed GONUTS page
- ↑ 4.0 4.1 Mount SM & Salz HK (2000) Pre-messenger RNA processing factors in the Drosophila genome. J Cell Biol 150: F37-44 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Herold N et al. (2009) Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol 29: 281-301 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Edenfeld G et al. (2006) The splicing factor crooked neck associates with the RNA-binding protein HOW to control glial cell maturation in Drosophila. Neuron 52: 969-80 PubMed GONUTS page
- ↑ Jack J & Myette G (1999) Mutations that alter the morphology of the malpighian tubules in Drosophila. Dev Genes Evol 209: 546-54 PubMed GONUTS page
- ↑ Raisin-Tani S & Léopold P (2002) Drosophila crooked-neck protein co-fractionates in a multiprotein complex with splicing factors. Biochem Biophys Res Commun 296: 288-92 PubMed GONUTS page
