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FB:cno

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) cno ( synonyms: AF-6, Afadin, CG2534, CG31537, CG42312, Canoe, Cno, afadin, anon-WO0172774.47, dlhA, dorsal holes A, lip, lips, mis, misty )
Protein Name(s) canoe,
External Links
FB FBgn0259212

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003779

actin binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:U83231

F

From FB

GO:0005912

adherens junction

FB:FBrf0110443
PMID:10449347[1]

TAS: Traceable Author Statement

C

From FB

GO:0005912

adherens junction

FB:FBrf0125331
PMID:10639730[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005912

adherens junction

FB:FBrf0127206
PMID:10790336[3]

TAS: Traceable Author Statement

C

From FB

GO:0005912

adherens junction

FB:FBrf0159915
PMID:12766944[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0005915

zonula adherens

FB:FBrf0141282
PMID:11700298[5]

TAS: Traceable Author Statement

C

From FB

GO:0005926

connecting hemi-adherens junction

FB:FBrf0208505
PMID:19596848[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0005938

cell cortex

FB:FBrf0187455
PMID:15843408[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0007163

establishment or maintenance of cell polarity

FB:FBrf0159915
PMID:12766944[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007219

Notch signaling pathway

FB:FBrf0141282
PMID:11700298[5]

TAS: Traceable Author Statement

P

From FB

GO:0007254

JNK cascade

FB:FBrf0110443
PMID:10449347[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0007265

Ras protein signal transduction

FB:FBrf0141282
PMID:11700298[5]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0110443
PMID:10449347[1]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0141282
PMID:11700298[5]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0162150
PMID:14504224[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007394

dorsal closure, elongation of leading edge cells

FB:FBrf0151280
PMID:12147138[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0016318

ommatidial rotation

FB:FBrf0167499
PMID:14507782[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046328

regulation of JNK cascade

FB:FBrf0151280
PMID:12147138[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0046328

regulation of JNK cascade

FB:FBrf0162150
PMID:14504224[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0000229

P

From FB

GO:0046328

regulation of JNK cascade

FB:FBrf0162150
PMID:14504224[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048598

embryonic morphogenesis

FB:FBrf0208505
PMID:19596848[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048730

epidermis morphogenesis

FB:FBrf0208505
PMID:19596848[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0195244
PMID:17097274[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0025743

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Noselli S & Agnès F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr Opin Genet Dev 9: 466-72 PubMed GONUTS page
  2. Matsuo T et al. (1999) The Canoe protein is necessary in adherens junctions for development of ommatidial architecture in the Drosophila compound eye. Cell Tissue Res 298: 397-404 PubMed GONUTS page
  3. Liu X & Lengyel JA (2000) Drosophila arc encodes a novel adherens junction-associated PDZ domain protein required for wing and eye development. Dev Biol 221: 419-34 PubMed GONUTS page
  4. 4.0 4.1 Humbert P et al. (2003) Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25: 542-53 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Tepass U et al. (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35: 747-84 PubMed GONUTS page
  6. 6.0 6.1 6.2 Sawyer JK et al. (2009) The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J Cell Biol 186: 57-73 PubMed GONUTS page
  7. Denholm B et al. (2005) crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis. Development 132: 2389-400 PubMed GONUTS page
  8. 8.0 8.1 8.2 Boettner B et al. (2003) The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics 165: 159-69 PubMed GONUTS page
  9. 9.0 9.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  10. Gaengel K & Mlodzik M (2003) Egfr signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6. Development 130: 5413-23 PubMed GONUTS page
  11. Menzel N et al. (2007) The Drosophila p21 activated kinase Mbt regulates the actin cytoskeleton and adherens junctions to control photoreceptor cell morphogenesis. Mech Dev 124: 78-90 PubMed GONUTS page
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