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FB:ck

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ck ( synonyms: 53D10S, BG:DS00929.11, CG7595, Crinkled, D, D2, DM7a, DMyoVIIa, Dm 35B, DmVIIA, DmVIIa, Dro35B, ESTS:53D10S, Mhc35BC, MyoVIIA, Myosin heavy chain at 35BC, anon-35Bb, br27, ck/MyoVIIA, l(1)35Ca, l(2)07130, l(2)35Ca, l(2)br27, l35Ca, lethal 27 in the black-reduced region, lethal group D2, myoVIIA, myosin 7a, myosin 7a heavy chain, myosin VII, myosin VIIA, myosin VIIa, myosin-VII, mysoin VIIa, stc, stch, stubby chaetae, transcription unit D )
Protein Name(s) crinkled,
External Links
FB FBgn0000317

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003774

motor activity

FB:FBrf0129830
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:613788

F

From FB

GO:0003779

actin binding

FB:FBrf0129830
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:613788

F

From FB

GO:0005524

ATP binding

FB:FBrf0190908
PMID:16415346[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0005524

ATP binding

FB:FBrf0191467
PMID:16585515[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0005902

microvillus

FB:FBrf0207539
PMID:19270738[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0007423

sensory organ development

FB:FBrf0210248
PMID:18461180[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007469

antennal development

FB:FBrf0210248
PMID:18461180[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007605

sensory perception of sound

FB:FBrf0187338
PMID:15886106[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0180276
PMID:15579689[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0183733
PMID:15596016[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0016977

P

From FB

GO:0016459

myosin complex

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0016461

unconventional myosin complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:U81453

C

From FB

GO:0016461

unconventional myosin complex

FB:FBrf0112152
PMID:10471707[9]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0016461

unconventional myosin complex

FB:FBrf0129830
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:613788

C

From FB

GO:0030048

actin filament-based movement

FB:FBrf0191467
PMID:16585515[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0030898

actin-dependent ATPase activity

FB:FBrf0190908
PMID:16415346[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0030898

actin-dependent ATPase activity

FB:FBrf0191467
PMID:16585515[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0030898

actin-dependent ATPase activity

FB:FBrf0207517
PMID:19255446[10]

IDA: Inferred from Direct Assay

F

From FB

GO:0032027

myosin light chain binding

FB:FBrf0193420
PMID:16917818[11]

IPI: Inferred from Physical Interaction

FB:FBgn0004687

F

From FB

GO:0035317

imaginal disc-derived wing hair organization

FB:FBrf0135688
PMID:11301004[12]

IGI: Inferred from Genetic Interaction

FB:FBgn0000499

P

From FB

GO:0035317

imaginal disc-derived wing hair organization

FB:FBrf0135688
PMID:11301004[12]

IGI: Inferred from Genetic Interaction

FB:FBgn0001085

P

From FB

GO:0035317

imaginal disc-derived wing hair organization

FB:FBrf0183733
PMID:15596016[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0016977

P

From FB

GO:0042623

ATPase activity, coupled

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0045179

apical cortex

FB:FBrf0207539
PMID:19270738[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0048800

antennal morphogenesis

FB:FBrf0148956
PMID:12070612[13]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  2. 2.0 2.1 Watanabe S et al. (2006) Drosophila myosin VIIA is a high duty ratio motor with a unique kinetic mechanism. J Biol Chem 281: 7151-60 PubMed GONUTS page
  3. 3.0 3.1 3.2 Yang Y et al. (2006) Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci U S A 103: 5746-51 PubMed GONUTS page
  4. 4.0 4.1 Demontis F & Dahmann C (2009) Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans. PLoS One 4: e4753 PubMed GONUTS page
  5. 5.0 5.1 Todi SV et al. (2008) Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development. PLoS One 3: e2115 PubMed GONUTS page
  6. Todi SV et al. (2005) Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila. Curr Biol 15: 862-8 PubMed GONUTS page
  7. Kiehart DP et al. (2004) Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA. Genetics 168: 1337-52 PubMed GONUTS page
  8. 8.0 8.1 Mace K & Tugores A (2004) The product of the split ends gene is required for the maintenance of positional information during Drosophila development. BMC Dev Biol 4: 15 PubMed GONUTS page
  9. Ashburner M et al. (1999) An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153: 179-219 PubMed GONUTS page
  10. Yang Y et al. (2009) A FERM domain autoregulates Drosophila myosin 7a activity. Proc Natl Acad Sci U S A 106: 4189-94 PubMed GONUTS page
  11. Franke JD et al. (2006) Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster. Cell Motil Cytoskeleton 63: 604-22 PubMed GONUTS page
  12. 12.0 12.1 Winter CG et al. (2001) Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell 105: 81-91 PubMed GONUTS page
  13. He B & Adler PN (2002) The genetic control of arista lateral morphogenesis in Drosophila. Dev Genes Evol 212: 218-29 PubMed GONUTS page
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