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FB:chico
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | chico ( synonyms: BcDNA.GH11263, BcDNA:GH11263, CG5686, CHICO, Chico, IRS, IRS/chico, Insulin receptor substrate, anon-WO0078940.1, anon-WO0078940.4, chic, dIRS, flipper, fs(2)4, fs(2)ry4, insulin receptor substrate, insulin-like receptor substrate ) | |
| Protein Name(s) | chico, | |
| External Links | ||
| FB | FBgn0024248 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000902 |
cell morphogenesis |
FB:FBrf0108621 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005158 |
insulin receptor binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0108621 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0013984 |
F |
From FB |
||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0108621 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:6125 |
F |
From FB |
||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0108621 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:6126 |
F |
From FB |
||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0113403 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005159 |
insulin-like growth factor receptor binding |
FB:FBrf0119010 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005543 |
phospholipid binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0007285 |
primary spermatocyte growth |
FB:FBrf0208094 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007295 |
growth of a germarium-derived egg chamber |
FB:FBrf0134545 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007296 |
vitellogenesis |
FB:FBrf0134545 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007568 |
aging |
FB:FBrf0135946 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008152 |
metabolic process |
FB:FBrf0156191 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0108621 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0013984 |
P |
From FB |
||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0108621 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0015279 |
P |
From FB |
||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0141377 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008286 |
insulin receptor signaling pathway |
FB:FBrf0156191 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0155558 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0155931 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0156109 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0156191 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0167266 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0090759 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008361 |
regulation of cell size |
FB:FBrf0156191 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030307 |
positive regulation of cell growth |
FB:FBrf0141377 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0034059 |
response to anoxia |
FB:FBrf0207966 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0035159 |
regulation of tube length, open tracheal system |
FB:FBrf0128394 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040014 |
regulation of multicellular organism growth |
FB:FBrf0156191 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0125443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0151278 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0156084 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0157335 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0040018 |
positive regulation of multicellular organism growth |
FB:FBrf0208858 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042594 |
response to starvation |
FB:FBrf0151278 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042594 |
response to starvation |
FB:FBrf0155931 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0125443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0130003 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0136845 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0156084 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0159230 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0156191 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046620 |
regulation of organ growth |
FB:FBrf0188217 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0125443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0136845 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046622 |
positive regulation of organ growth |
FB:FBrf0156084 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048133 |
male germ-line stem cell division |
FB:FBrf0208094 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0060250 |
germ-line stem-cell niche homeostasis |
FB:FBrf0206962 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Böhni R et al. (1999) Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97: 865-75 PubMed GONUTS page
- ↑ 2.0 2.1 Ueishi S et al. (2009) Male germline stem cell division and spermatocyte growth require insulin signaling in Drosophila. Cell Struct Funct 34: 61-9 PubMed GONUTS page
- ↑ 3.0 3.1 Drummond-Barbosa D & Spradling AC (2001) Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Dev Biol 231: 265-78 PubMed GONUTS page
- ↑ Clancy DJ et al. (2001) Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292: 104-6 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Claeys I et al. (2002) Insulin-related peptides and their conserved signal transduction pathway. Peptides 23: 807-16 PubMed GONUTS page
- ↑ 6.0 6.1 Johnston LA & Gallant P (2002) Control of growth and organ size in Drosophila. Bioessays 24: 54-64 PubMed GONUTS page
- ↑ Helfand SL & Rogina B (2003) Molecular genetics of aging in the fly: is this the end of the beginning? Bioessays 25: 134-41 PubMed GONUTS page
- ↑ 8.0 8.1 Aigaki T et al. (2002) Longevity determination genes in Drosophila melanogaster. Mech Ageing Dev 123: 1531-41 PubMed GONUTS page
- ↑ Wolkow CA (2002) Life span: getting the signal from the nervous system. Trends Neurosci 25: 212-6 PubMed GONUTS page
- ↑ Helfand SL & Rogina B (2003) Genetics of aging in the fruit fly, Drosophila melanogaster. Annu Rev Genet 37: 329-48 PubMed GONUTS page
- ↑ Riesgo-Escovar JR et al. (1996) The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes Dev 10: 2759-68 PubMed GONUTS page
- ↑ Vigne P et al. (2009) Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries. PLoS One 4: e5422 PubMed GONUTS page
- ↑ Beitel GJ & Krasnow MA (2000) Genetic control of epithelial tube size in the Drosophila tracheal system. Development 127: 3271-82 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Weinkove D & Leevers SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr Opin Genet Dev 10: 75-80 PubMed GONUTS page
- ↑ 15.0 15.1 Oldham S et al. (2000) Genetic control of size in Drosophila. Philos Trans R Soc Lond B Biol Sci 355: 945-52 PubMed GONUTS page
- ↑ 16.0 16.1 Oldham S et al. (2002) The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development 129: 4103-9 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 Oldham S & Hafen E (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol 13: 79-85 PubMed GONUTS page
- ↑ Gumienny TL & Padgett RW (2003) A small issue addressed. Bioessays 25: 305-8 PubMed GONUTS page
- ↑ Parrish JZ et al. (2009) The microRNA bantam functions in epithelial cells to regulate scaling growth of dendrite arbors in drosophila sensory neurons. Neuron 63: 788-802 PubMed GONUTS page
- ↑ 20.0 20.1 Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ Jacinto E & Hall MN (2003) Tor signalling in bugs, brain and brawn. Nat Rev Mol Cell Biol 4: 117-26 PubMed GONUTS page
- ↑ Shingleton AW et al. (2005) The temporal requirements for insulin signaling during development in Drosophila. PLoS Biol 3: e289 PubMed GONUTS page
- ↑ Hsu HJ & Drummond-Barbosa D (2009) Insulin levels control female germline stem cell maintenance via the niche in Drosophila. Proc Natl Acad Sci U S A 106: 1117-21 PubMed GONUTS page
