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FB:chic

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) chic ( synonyms: CG9553, Chi, Chic, Chickadee, D88, DProfilin, GH4, Profilin, chi, chickaddee, l(2)27/7, profilin, sand, stranded )
Protein Name(s) chickadee,
External Links
FB FBgn0000308

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000902

cell morphogenesis

FB:FBrf0162189
PMID:12975351[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000902

cell morphogenesis

FB:FBrf0212211
PMID:21041442[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0180064
PMID:15380073[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0191432
PMID:16174742[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000915

cytokinesis, actomyosin contractile ring assembly

FB:FBrf0151773
PMID:12386932[5]

TAS: Traceable Author Statement

P

From FB

GO:0003779

actin binding

FB:FBrf0123868

NAS: Non-traceable Author Statement

F

From FB

GO:0003779

actin binding

FB:FBrf0132100
PMID:10908588[6]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003779

actin binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002097
InterPro:IPR005455

F

From FB

GO:0005515

protein binding

FB:FBrf0108135
PMID:10220404[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q8T4F7

F

From FB

GO:0005515

protein binding

FB:FBrf0207596
PMID:19279137[8]

IPI: Inferred from Physical Interaction

FB:FBgn0011202

F

From FB

GO:0005546

phosphatidylinositol-4,5-bisphosphate binding

FB:FBrf0123868

NAS: Non-traceable Author Statement

F

From FB

GO:0007015

actin filament organization

FB:FBrf0132269
PMID:11139280[9]

TAS: Traceable Author Statement

P

From FB

GO:0007015

actin filament organization

FB:FBrf0139770
PMID:11584269[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007283

spermatogenesis

FB:FBrf0064394
PMID:8244010[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007300

ovarian nurse cell to oocyte transport

FB:FBrf0054123
PMID:1783295[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0149002
PMID:12000787[13]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[14]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151872
PMID:12231351[15]

TAS: Traceable Author Statement

P

From FB

GO:0007411

axon guidance

FB:FBrf0210319
PMID:18516287[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007420

brain development

FB:FBrf0129736
PMID:11030623[17]

IGI: Inferred from Genetic Interaction

FB:FBgn0026084

P

From FB

GO:0007420

brain development

FB:FBrf0187329
PMID:15964283[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007488

histoblast morphogenesis

FB:FBrf0194691
PMID:17166923[19]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008154

actin polymerization or depolymerization

FB:FBrf0123868

NAS: Non-traceable Author Statement

P

From FB

GO:0015629

actin cytoskeleton

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002097

C

From FB

GO:0030041

actin filament polymerization

FB:FBrf0151280
PMID:12147138[14]

TAS: Traceable Author Statement

P

From FB

GO:0030717

karyosome formation

FB:FBrf0187382
PMID:15979065[20]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0032507

maintenance of protein location in cell

FB:FBrf0191432
PMID:16174742[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035193

larval central nervous system remodeling

FB:FBrf0129736
PMID:11030623[17]

IGI: Inferred from Genetic Interaction

FB:FBgn0026084

P

From FB

GO:0045451

pole plasm oskar mRNA localization

FB:FBrf0141280
PMID:11700288[21]

TAS: Traceable Author Statement

P

From FB

GO:0051491

positive regulation of filopodium assembly

FB:FBrf0213367
PMID:21464901[22]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Rogers SL et al. (2003) Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol 162: 1079-88 PubMed GONUTS page
  2. D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
  3. Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
  4. 4.0 4.1 Dean SO et al. (2005) Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci U S A 102: 13473-8 PubMed GONUTS page
  5. Mazumdar A & Mazumdar M (2002) How one becomes many: blastoderm cellularization in Drosophila melanogaster. Bioessays 24: 1012-22 PubMed GONUTS page
  6. Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  7. Ahern-Djamali SM et al. (1999) Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled. Proc Natl Acad Sci U S A 96: 4977-82 PubMed GONUTS page
  8. Webb RL et al. (2009) A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila. Development 136: 1283-93 PubMed GONUTS page
  9. Buszczak M & Cooley L (2000) Eggs to die for: cell death during Drosophila oogenesis. Cell Death Differ 7: 1071-4 PubMed GONUTS page
  10. Baum B & Perrimon N (2001) Spatial control of the actin cytoskeleton in Drosophila epithelial cells. Nat Cell Biol 3: 883-90 PubMed GONUTS page
  11. Castrillon DH et al. (1993) Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics 135: 489-505 PubMed GONUTS page
  12. Schüpbach T & Wieschaus E (1991) Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. Genetics 129: 1119-36 PubMed GONUTS page
  13. Van Aelst L & Symons M (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 16: 1032-54 PubMed GONUTS page
  14. 14.0 14.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  15. Martin P & Wood W (2002) Epithelial fusions in the embryo. Curr Opin Cell Biol 14: 569-74 PubMed GONUTS page
  16. Berger J et al. (2008) Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system. PLoS Genet 4: e1000085 PubMed GONUTS page
  17. 17.0 17.1 Boquet I et al. (2000) Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell 102: 797-808 PubMed GONUTS page
  18. Reeve SP et al. (2005) The Drosophila fragile X mental retardation protein controls actin dynamics by directly regulating profilin in the brain. Curr Biol 15: 1156-63 PubMed GONUTS page
  19. Ninov N et al. (2007) Extrinsic and intrinsic mechanisms directing epithelial cell sheet replacement during Drosophila metamorphosis. Development 134: 367-79 PubMed GONUTS page
  20. Djagaeva I et al. (2005) Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis. Dev Biol 284: 143-56 PubMed GONUTS page
  21. Johnstone O & Lasko P (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet 35: 365-406 PubMed GONUTS page
  22. Gonçalves-Pimentel C et al. (2011) Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model. PLoS One 6: e18340 PubMed GONUTS page
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