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FB:chb
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | chb ( synonyms: 0686/07, BcDNA:LD31673, CG32435, CLASP, Chb, DMAP160, MAST, MAST/Orbit, MESR7, Mast, Mast/Orbit, Misexpression suppressor of ras 7, NEST:bs13a06, NEST:bs17d05, NEST:bs28g05, Orbit, Orbit/MAST, Orbit/Mast, Orbit/Mast/CLASP, anon-WO0104295, chb(v40), clasp, mast, mast/orbit, multiple asters, orb, orbit, orbit/MAST, orbit/clasp, orbit/mast, v40 ) | |
| Protein Name(s) | chromosome bows, | |
| External Links | ||
| FB | FBgn0021760 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000022 |
mitotic spindle elongation |
FB:FBrf0149065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000022 |
mitotic spindle elongation |
FB:FBrf0190017 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000022 |
mitotic spindle elongation |
FB:FBrf0200397 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000070 |
mitotic sister chromatid segregation |
FB:FBrf0128546 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000775 |
chromosome, centromeric region |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0000922 |
spindle pole |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005525 |
GTP binding |
FB:FBrf0127132 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0127132 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005813 |
centrosome |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005815 |
microtubule organizing center |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005827 |
polar microtubule |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0127132 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005876 |
spindle microtubule |
FB:FBrf0127132 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005876 |
spindle microtubule |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005876 |
spindle microtubule |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007051 |
spindle organization |
FB:FBrf0127132 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007052 |
mitotic spindle organization |
FB:FBrf0128546 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007052 |
mitotic spindle organization |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007067 |
mitosis |
FB:FBrf0127132 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007067 |
mitosis |
FB:FBrf0149065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007282 |
cystoblast division |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0179303 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008017 |
microtubule binding |
FB:FBrf0127132 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008017 |
microtubule binding |
FB:FBrf0128546 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0016325 |
oocyte microtubule cytoskeleton organization |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019827 |
stem cell maintenance |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030723 |
ovarian fusome organization |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035099 |
hemocyte migration |
FB:FBrf0210787 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040001 |
establishment of mitotic spindle localization |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043148 |
mitotic spindle stabilization |
FB:FBrf0149065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045169 |
fusome |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045172 |
germline ring canal |
FB:FBrf0155725 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0046602 |
regulation of mitotic centrosome separation |
FB:FBrf0149065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0155725 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051225 |
spindle assembly |
FB:FBrf0179258 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051315 |
attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation |
FB:FBrf0149065 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0000776 |
kinetochore |
FB:FBrf0200397 |
IDA: Inferred from Direct Assay |
C |
From FB |
||
|
colocalizes_with |
GO:0005819 |
spindle |
FB:FBrf0200397 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Maiato H et al. (2002) MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J Cell Biol 157: 749-60 PubMed GONUTS page
- ↑ Goshima G et al. (2005) Length control of the metaphase spindle. Curr Biol 15: 1979-88 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Lemos CL et al. (2000) Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. EMBO J 19: 3668-82 PubMed GONUTS page
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 Máthé E et al. (2003) Orbit/Mast, the CLASP orthologue of Drosophila, is required for asymmetric stem cell and cystocyte divisions and development of the polarised microtubule network that interconnects oocyte and nurse cells during oogenesis. Development 130: 901-15 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 Inoue YH et al. (2000) Orbit, a novel microtubule-associated protein essential for mitosis in Drosophila melanogaster. J Cell Biol 149: 153-66 PubMed GONUTS page
- ↑ Lee H et al. (2004) The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance. Neuron 42: 913-26 PubMed GONUTS page
- ↑ Stramer B et al. (2010) Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion in Drosophila macrophages in vivo. J Cell Biol 189: 681-9 PubMed GONUTS page
- ↑ Inoue YH et al. (2004) Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression. J Cell Biol 166: 49-60 PubMed GONUTS page
