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FB:cdc2
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | cdc2 ( synonyms: 5363, CDC2, CDC2 kinase, CDCDm, CDK1, CDK1/CDC2, CG5363, Cdc2, Cdc2 kinase, Cdk-1, Cdk1, Dcdc2, Dm cdc2, DmCdc2, DmCdk1, Dmcdc2, cdc, cdc2 kinase, cdc2Dm, cdk1, cyclin dependent kinase, cyclin-dependent kinase, cyclin-dependent kinase 1, group 4, l(2)31Eh ) | |
| Protein Name(s) | cdc2, | |
| External Links | ||
| FB | FBgn0004106 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000082 |
G1/S transition of mitotic cell cycle |
FB:FBrf0051651 |
IGI: Inferred from Genetic Interaction |
SGD:S000000364 |
P |
From FB |
||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
FB:FBrf0051651 |
IGI: Inferred from Genetic Interaction |
SGD:S000000364 |
P |
From FB |
||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
FB:FBrf0058077 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004693 |
cyclin-dependent protein kinase activity |
FB:FBrf0051651 |
IGI: Inferred from Genetic Interaction |
SGD:S000000364 |
F |
From FB |
||
| GO:0004693 |
cyclin-dependent protein kinase activity |
FB:FBrf0051651 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S000000364 |
F |
From FB |
||
| GO:0004693 |
cyclin-dependent protein kinase activity |
FB:FBrf0123812 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004693 |
cyclin-dependent protein kinase activity |
FB:FBrf0161937 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0105853 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015625 |
F |
From FB |
||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123812 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0161937 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0087034 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007049 |
cell cycle |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007140 |
male meiosis |
FB:FBrf0187466 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007141 |
male meiosis I |
FB:FBrf0105828 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007283 |
spermatogenesis |
FB:FBrf0105828 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007284 |
spermatogonial cell division |
FB:FBrf0187466 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008315 |
meiotic G2/MI transition |
FB:FBrf0105828 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009987 |
cellular process |
FB:FBrf0175143 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0032880 |
regulation of protein localization |
FB:FBrf0151365 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048142 |
germarium-derived cystoblast division |
FB:FBrf0187466 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0123812 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0161937 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0055059 |
asymmetric neuroblast division |
FB:FBrf0134790 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0055059 |
asymmetric neuroblast division |
FB:FBrf0156163 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
FB:FBrf0123812 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0070816 |
phosphorylation of RNA polymerase II C-terminal domain |
FB:FBrf0161937 |
NAS: Non-traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Lehner CF & O'Farrell PH (1990) Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant. EMBO J 9: 3573-81 PubMed GONUTS page
- ↑ Stern B et al. (1993) Genetic analysis of the Drosophila cdc2 homolog. Development 117: 219-32 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Jacobs HW et al. (1998) Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev 12: 3741-51 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ Du W et al. (1996) RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev 10: 1206-18 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
- ↑ Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Jin Z et al. (2005) Drosophila Myt1 is a Cdk1 inhibitory kinase that regulates multiple aspects of cell cycle behavior during gametogenesis. Development 132: 4075-85 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Fuller MT (1998) Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol 9: 433-44 PubMed GONUTS page
- ↑ Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
- ↑ Royou A et al. (2002) Cortical recruitment of nonmuscle myosin II in early syncytial Drosophila embryos: its role in nuclear axial expansion and its regulation by Cdc2 activity. J Cell Biol 158: 127-37 PubMed GONUTS page
- ↑ Tio M et al. (2001) cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature 409: 1063-7 PubMed GONUTS page
- ↑ Schaefer M & Knoblich JA (2001) Protein localization during asymmetric cell division. Exp Cell Res 271: 66-74 PubMed GONUTS page
